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2015长城会：张萍教授：从指南看房颤抗凝策略的变迁

2015-11-02 北京清华长庚医院 张萍 中国医学论坛报

张萍教授房颤抗凝策略
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第二十六届长城国际心脏病学会议 第九届北京五洲国际心血管病会议2015 亚太心脏大会暨国际心血管病预防与康复会议2015    房颤患者卒中风险升高5倍，无论阵发性、持续性，有症状、无症状的房颤都将显著增加血栓性卒中风险，因此抗凝治疗已成为房颤的基本治疗策略。但在房颤抗凝治疗过程中需要评估卒中风险与获益，同时还需选择适宜的抗凝药物。 缺血性卒中风险评

第二十六届长城国际心脏病学会议

第九届北京五洲国际心血管病会议2015

亚太心脏大会暨国际心血管病预防与康复会议2015   

房颤患者卒中风险升高5倍，无论阵发性、持续性，有症状、无症状的房颤都将显著增加血栓性卒中风险，因此抗凝治疗已成为房颤的基本治疗策略。但在房颤抗凝治疗过程中需要评估卒中风险与获益，同时还需选择适宜的抗凝药物。

缺血性卒中风险评分变迁2006年欧洲心脏病学会(ESC)房颤指南推荐了评估房颤患者发生血栓栓塞风险的CHADS2评分方法：有充血性心力衰竭、高血压、年龄≥75岁和糖尿病各得1分，有卒中、短暂性脑缺血发作(TIA)或栓塞病史加2分，总分6分。2010年指南更新时又提出了CHA2DS2-VASc 评分法：血管疾病、女性、年龄65~74岁各加1分，年龄≥75 岁提升至加2分，总分9分。但2013年美国心脏学会(AHA)、美国心脏病学会(ACC)和美国心律学会(HRS)颁布的房颤管理指南未接受新的评分系统，直到2014年才接受，并指出这一评分系统可更好地识别低风险患者。

抗凝药物推荐不断变化对于非瓣膜性房颤，CHA2DS2-VASc评分为0时，所有指南均不提倡抗栓治疗；对于有卒中史、TIA 或CHA2DS2-VASc 评分≥2 分的患者，新指南推荐既可应用华法林，也可考虑NOACs(包括达比加群、利伐沙班、阿哌沙班)，华法林和NOACs的选择是平行推荐，没有先后。为保证抗凝治疗的安全性，2014年的房颤指南推荐了应用华法林时INR值监测的周期以及慢性肾脏功能不全患者的抗凝治疗策略。对于瓣膜性房颤患者推荐应用华法林。对于肥厚型心肌病患者推荐直接应用抗凝治疗，不需CHA2DS2-VASc 评分。对ACS 合并房颤且CHA2DS2-VASc 评分≥2 分的患者，推荐华法林抗凝，由于循证依据不足，没有推荐NOACs。2014 年的房颤管理指南使NOACs的地位提升，抗血小板治疗的地位下降。

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    2016-01-27 xiongke020

    #房颤抗凝#

    0

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    2016-01-28 ymljack

    #抗凝策略#

    0

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    2016-09-29 Homburg

    #张萍教授#

    0

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    2015-11-03 wsusan1966

    #长城会#

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1694811, encodeId=7028169481123, content=<a href='/topic/show?id=a7385426313' target=_blank style='color:#2F92EE;'>#房颤抗凝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54263, encryptionId=a7385426313, topicName=房颤抗凝)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8df129768056, createdName=xiongke020, createdTime=Wed Jan 27 04:57:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1976022, encodeId=8db619e6022db, content=<a href='/topic/show?id=9f71552368f' target=_blank style='color:#2F92EE;'>#抗凝策略#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55236, encryptionId=9f71552368f, topicName=抗凝策略)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=460849, createdName=ymljack, createdTime=Thu Jan 28 20:57:00 CST 2016, time=2016-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2080753, encodeId=94e52080e53db, content=<a href='/topic/show?id=d1a150001b0' target=_blank style='color:#2F92EE;'>#张萍教授#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50001, encryptionId=d1a150001b0, topicName=张萍教授)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e87d405, createdName=Homburg, createdTime=Thu Sep 29 17:57:00 CST 2016, time=2016-09-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1322735, encodeId=09071322e3537, content=<a href='/topic/show?id=355b96891fe' target=_blank style='color:#2F92EE;'>#长城会#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96891, encryptionId=355b96891fe, topicName=长城会)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ef33504, createdName=wsusan1966, createdTime=Tue Nov 03 23:57:00 CST 2015, time=2015-11-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42334, encodeId=afe84233417, content=及时信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2be01625436, createdName=fatalmelanie, createdTime=Mon Nov 02 16:02:00 CST 2015, time=2015-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42335, encodeId=089a4233572, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2be01625436, createdName=fatalmelanie, createdTime=Mon Nov 02 16:02:00 CST 2015, time=2015-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42195, encodeId=a2f842195cf, content=谢谢啦！, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ded71629504, createdName=nizongzan, createdTime=Mon Nov 02 12:32:00 CST 2015, time=2015-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42196, encodeId=c5a842196ed, content=最新的信息，节省时间了解动态, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ded71629504, createdName=nizongzan, createdTime=Mon Nov 02 12:32:00 CST 2015, time=2015-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42197, encodeId=d9064219e00, content=学到好多东西, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ded71629504, createdName=nizongzan, createdTime=Mon Nov 02 12:32:00 CST 2015, time=2015-11-02, status=1, ipAttribution=)]
    2015-11-02 fatalmelanie

    及时信息

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1694811, encodeId=7028169481123, content=<a href='/topic/show?id=a7385426313' target=_blank style='color:#2F92EE;'>#房颤抗凝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54263, encryptionId=a7385426313, topicName=房颤抗凝)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8df129768056, createdName=xiongke020, createdTime=Wed Jan 27 04:57:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1976022, encodeId=8db619e6022db, content=<a href='/topic/show?id=9f71552368f' target=_blank style='color:#2F92EE;'>#抗凝策略#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55236, encryptionId=9f71552368f, topicName=抗凝策略)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=460849, createdName=ymljack, createdTime=Thu Jan 28 20:57:00 CST 2016, time=2016-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2080753, encodeId=94e52080e53db, content=<a href='/topic/show?id=d1a150001b0' target=_blank style='color:#2F92EE;'>#张萍教授#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50001, encryptionId=d1a150001b0, topicName=张萍教授)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e87d405, createdName=Homburg, createdTime=Thu Sep 29 17:57:00 CST 2016, time=2016-09-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1322735, encodeId=09071322e3537, content=<a href='/topic/show?id=355b96891fe' target=_blank style='color:#2F92EE;'>#长城会#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96891, encryptionId=355b96891fe, topicName=长城会)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ef33504, createdName=wsusan1966, createdTime=Tue Nov 03 23:57:00 CST 2015, time=2015-11-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42334, encodeId=afe84233417, content=及时信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2be01625436, createdName=fatalmelanie, createdTime=Mon Nov 02 16:02:00 CST 2015, time=2015-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42335, encodeId=089a4233572, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2be01625436, createdName=fatalmelanie, createdTime=Mon Nov 02 16:02:00 CST 2015, time=2015-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42195, encodeId=a2f842195cf, content=谢谢啦！, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ded71629504, createdName=nizongzan, createdTime=Mon Nov 02 12:32:00 CST 2015, time=2015-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42196, encodeId=c5a842196ed, content=最新的信息，节省时间了解动态, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ded71629504, createdName=nizongzan, createdTime=Mon Nov 02 12:32:00 CST 2015, time=2015-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42197, encodeId=d9064219e00, content=学到好多东西, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ded71629504, createdName=nizongzan, createdTime=Mon Nov 02 12:32:00 CST 2015, time=2015-11-02, status=1, ipAttribution=)]
    2015-11-02 fatalmelanie

    赞

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1694811, encodeId=7028169481123, content=<a href='/topic/show?id=a7385426313' target=_blank style='color:#2F92EE;'>#房颤抗凝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54263, encryptionId=a7385426313, topicName=房颤抗凝)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8df129768056, createdName=xiongke020, createdTime=Wed Jan 27 04:57:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1976022, encodeId=8db619e6022db, content=<a href='/topic/show?id=9f71552368f' target=_blank style='color:#2F92EE;'>#抗凝策略#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55236, encryptionId=9f71552368f, topicName=抗凝策略)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=460849, createdName=ymljack, createdTime=Thu Jan 28 20:57:00 CST 2016, time=2016-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2080753, encodeId=94e52080e53db, content=<a href='/topic/show?id=d1a150001b0' target=_blank style='color:#2F92EE;'>#张萍教授#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50001, encryptionId=d1a150001b0, topicName=张萍教授)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e87d405, createdName=Homburg, createdTime=Thu Sep 29 17:57:00 CST 2016, time=2016-09-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1322735, encodeId=09071322e3537, content=<a href='/topic/show?id=355b96891fe' target=_blank style='color:#2F92EE;'>#长城会#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96891, encryptionId=355b96891fe, topicName=长城会)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ef33504, createdName=wsusan1966, createdTime=Tue Nov 03 23:57:00 CST 2015, time=2015-11-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42334, encodeId=afe84233417, content=及时信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2be01625436, createdName=fatalmelanie, createdTime=Mon Nov 02 16:02:00 CST 2015, time=2015-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42335, encodeId=089a4233572, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2be01625436, createdName=fatalmelanie, createdTime=Mon Nov 02 16:02:00 CST 2015, time=2015-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42195, encodeId=a2f842195cf, content=谢谢啦！, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ded71629504, createdName=nizongzan, createdTime=Mon Nov 02 12:32:00 CST 2015, time=2015-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42196, encodeId=c5a842196ed, content=最新的信息，节省时间了解动态, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ded71629504, createdName=nizongzan, createdTime=Mon Nov 02 12:32:00 CST 2015, time=2015-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42197, encodeId=d9064219e00, content=学到好多东西, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ded71629504, createdName=nizongzan, createdTime=Mon Nov 02 12:32:00 CST 2015, time=2015-11-02, status=1, ipAttribution=)]
    2015-11-02 nizongzan

    谢谢啦！

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1694811, encodeId=7028169481123, content=<a href='/topic/show?id=a7385426313' target=_blank style='color:#2F92EE;'>#房颤抗凝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54263, encryptionId=a7385426313, topicName=房颤抗凝)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8df129768056, createdName=xiongke020, createdTime=Wed Jan 27 04:57:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1976022, encodeId=8db619e6022db, content=<a href='/topic/show?id=9f71552368f' target=_blank style='color:#2F92EE;'>#抗凝策略#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55236, encryptionId=9f71552368f, topicName=抗凝策略)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=460849, createdName=ymljack, createdTime=Thu Jan 28 20:57:00 CST 2016, time=2016-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2080753, encodeId=94e52080e53db, content=<a href='/topic/show?id=d1a150001b0' target=_blank style='color:#2F92EE;'>#张萍教授#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50001, encryptionId=d1a150001b0, topicName=张萍教授)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e87d405, createdName=Homburg, createdTime=Thu Sep 29 17:57:00 CST 2016, time=2016-09-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1322735, encodeId=09071322e3537, content=<a href='/topic/show?id=355b96891fe' target=_blank style='color:#2F92EE;'>#长城会#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96891, encryptionId=355b96891fe, topicName=长城会)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ef33504, createdName=wsusan1966, createdTime=Tue Nov 03 23:57:00 CST 2015, time=2015-11-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42334, encodeId=afe84233417, content=及时信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2be01625436, createdName=fatalmelanie, createdTime=Mon Nov 02 16:02:00 CST 2015, time=2015-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42335, encodeId=089a4233572, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2be01625436, createdName=fatalmelanie, createdTime=Mon Nov 02 16:02:00 CST 2015, time=2015-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42195, encodeId=a2f842195cf, content=谢谢啦！, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ded71629504, createdName=nizongzan, createdTime=Mon Nov 02 12:32:00 CST 2015, time=2015-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42196, encodeId=c5a842196ed, content=最新的信息，节省时间了解动态, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ded71629504, createdName=nizongzan, createdTime=Mon Nov 02 12:32:00 CST 2015, time=2015-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42197, encodeId=d9064219e00, content=学到好多东西, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ded71629504, createdName=nizongzan, createdTime=Mon Nov 02 12:32:00 CST 2015, time=2015-11-02, status=1, ipAttribution=)]
    2015-11-02 nizongzan

    最新的信息，节省时间了解动态

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1694811, encodeId=7028169481123, content=<a href='/topic/show?id=a7385426313' target=_blank style='color:#2F92EE;'>#房颤抗凝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54263, encryptionId=a7385426313, topicName=房颤抗凝)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8df129768056, createdName=xiongke020, createdTime=Wed Jan 27 04:57:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1976022, encodeId=8db619e6022db, content=<a href='/topic/show?id=9f71552368f' target=_blank style='color:#2F92EE;'>#抗凝策略#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55236, encryptionId=9f71552368f, topicName=抗凝策略)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=460849, createdName=ymljack, createdTime=Thu Jan 28 20:57:00 CST 2016, time=2016-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2080753, encodeId=94e52080e53db, content=<a href='/topic/show?id=d1a150001b0' target=_blank style='color:#2F92EE;'>#张萍教授#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50001, encryptionId=d1a150001b0, topicName=张萍教授)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e87d405, createdName=Homburg, createdTime=Thu Sep 29 17:57:00 CST 2016, time=2016-09-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1322735, encodeId=09071322e3537, content=<a href='/topic/show?id=355b96891fe' target=_blank style='color:#2F92EE;'>#长城会#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96891, encryptionId=355b96891fe, topicName=长城会)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ef33504, createdName=wsusan1966, createdTime=Tue Nov 03 23:57:00 CST 2015, time=2015-11-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42334, encodeId=afe84233417, content=及时信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2be01625436, createdName=fatalmelanie, createdTime=Mon Nov 02 16:02:00 CST 2015, time=2015-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42335, encodeId=089a4233572, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2be01625436, createdName=fatalmelanie, createdTime=Mon Nov 02 16:02:00 CST 2015, time=2015-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42195, encodeId=a2f842195cf, content=谢谢啦！, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ded71629504, createdName=nizongzan, createdTime=Mon Nov 02 12:32:00 CST 2015, time=2015-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42196, encodeId=c5a842196ed, content=最新的信息，节省时间了解动态, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ded71629504, createdName=nizongzan, createdTime=Mon Nov 02 12:32:00 CST 2015, time=2015-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42197, encodeId=d9064219e00, content=学到好多东西, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ded71629504, createdName=nizongzan, createdTime=Mon Nov 02 12:32:00 CST 2015, time=2015-11-02, status=1, ipAttribution=)]
    2015-11-02 nizongzan

    学到好多东西

    0

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