JAMA Surg:胃肠外科手术后再住院率与患者术前血红蛋白水平、术后血糖水平息息相关。

2017-07-30 xuyihan MedSci原创

我们都知道外科手术患者术前如果有高血糖病史术后结局一般都比较不理想,但是术前血红蛋白水平或者是术后血糖水平也会影响患者手术后的结局呢?最近有一项研究就这方面进行了探讨。

我们都知道外科手术患者术前如果有高血糖病史术后结局一般都比较不理想,但是术前血红蛋白水平或者是术后血糖水平也会影响患者手术后的结局呢?最近有一项研究就这方面进行了探讨。

研究人员回顾性分析了2007年至2014年间在Veterans Affairs医院行胃肠手术的21541名患者,术后三天出现感染的患者排除在外,术前血红蛋白水平被定义为一个连续变量和分类变量(<5.7%, 5.7%-6.5%, 和>6.5%),采用logistics回归模型分析术后并发症和再住院率与术前血红蛋白水平(术前90天)和高血糖(术后48小时)的关系。

结果显示:在这21541名患者中,1193名患者是女性,平均年龄为63.7岁,共有23094例手术测量了术前血红蛋白和术后血糖水平,手术后并发症和30天内再住院率分别为27.2%和14.7%。对于HbA1c,术后葡萄糖水平,术后胰岛素用量,是否为糖尿病,体重指数等指标进行logistics回归模型后,术后血糖高于250mg/dL与30天内再住院增加有明显相关关系,相反的,术前血红蛋白水平高于6.5%则会减少再住院率。

所以研究人员得出一个结论,术后早期血糖水平会影响再住院率,术前血红蛋白水平高则是一个保护因素,所以患者术前的营养支持与术后的血糖控制就变得格外重要。

原始出处:

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