新型长链非编码RNA(lncRNA)的生物信息学研究进展

2014-01-03 原佳沛,张浩文,鲁志 生物化学与生物物理学进展

   非编码RNA (noncoding RNA,ncRNA)是指不被翻译成蛋白质的一类RNA,近几年来关于它们的功能研究越来越引起人们的重视.现在已经发现了一些中小型ncRNA,比如 microRNA、snoRNA、tRNA等,但是关于长ncRNA(lncRNA)的研究还不够完善.本篇综述回顾了 ncRNA特别是 lncRNA的生物信息学研究进展,包括它们的研究历程

   非编码RNA (noncoding RNA,ncRNA)是指不被翻译成蛋白质的一类RNA,近几年来关于它们的功能研究越来越引起人们的重视.现在已经发现了一些中小型ncRNA,比如 microRNA、snoRNA、tRNA等,但是关于长ncRNA(lncRNA)的研究还不够完善.本篇综述回顾了 ncRNA特别是 lncRNA的生物信息学研究进展,包括它们的研究历程、基本特点、与疾病的关系,以及对已有的预测非编码RNA的计算机方法进行了分析和比较,并且介绍 了利用机器学习模型整合新一代高通量测序数据的方法.
新型长链非编码RNA(lncRNA)的生物信息学研究进展.pdf

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    2014-02-14 d830384
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    2014-02-02 张伟

    生物信息

    0

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    2014-01-05 xzw113
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