Eur Urol:前列腺癌中的标准化和简化机器人辅助超扩展盆腔淋巴结清扫术

2020-05-03 AlexYang MedSci原创

在经历根治性前列腺切除术(RP)的中等风险和高风险前列腺癌(PCa)患者中,扩展盆腔淋巴结清扫术(ePLND)仍旧是淋巴结分期最准确的方法。而在非常高风险PCa患者中可以考虑使用超扩展盆腔淋巴结清扫术

在经历根治性前列腺切除术(RP)的中等风险和高风险前列腺癌(PCa)患者中,扩展盆腔淋巴结清扫术(ePLND)仍旧是淋巴结分期最准确的方法。而在非常高风险PCa患者中可以考虑使用超扩展盆腔淋巴结清扫术(sePLND)。

最近,有研究人员阐释了PCa的RP期间使用的一种可重复的sePLND机器人辅助技术。研究的时间为2016年6月到2019年8月,共包括了41名连续性的具有非常高风险淋巴结浸润(LNI)的局部PCa患者,他们接受了机器人辅助RP和标准的10步整体ePLND,随后进行了5步整体ssPLND。研究发现,41名患者接受了sePLND,结点清除数目中值(IQR)为23(19-29)。手术时间(包括RP、ePLND和sePLND)中值为256分钟。术前前列腺特异性抗原中值为12ng/ml(IQR 6.45-17.6)。10名(24.4%)患者的疾病阶段pT<3,9名(22%)患者为pT3a,21名(51.2%)患者为pT3b,1名患者为pT4。在治疗的患者中,54%接受了LNI:5名(4.9%)为单一结点,5名(4.9%)名2-5个结点,12名(29.3%)多于5个结点。围手术期并发症中,3名(7.3%)患者具有Clavien I-II并发症,4名(9.7%)患者具有Clavien≥III并发症。住院中值为6天。没有患者术后进行输血。

最后,研究人员指出,5步sePLND是非常高LNI风险PCa患者中的一种可重复和可行技术。

原始出处:

Mattei A, Würnschimmel C, Baumeister P et al. Standardized and Simplified Robot-assisted Superextended Pelvic Lymph Node Dissection for Prostate Cancer: The Monoblock Technique. Eur Urol. 20 April 2020

 

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    2020-05-04 sodoo
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    2020-05-04 xue8602
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    2020-05-03 misszhang

    前列腺癌相关研究,学习了,谢谢梅斯

    0

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