中国实体器官移植受者侵袭性真菌病临床诊治指南

2016-11-19 《中华医学杂志》 《中华医学杂志》

中华医学会器官移植学分会和中国医师协会器官移植医师分会结合更新的国内外临床证据,并参考2013年中国侵袭性真菌感染工作组的《血液病/恶性肿瘤患者侵袭性真菌病的诊断标准与治疗原则(第四次修订版)》、美国感染学会(IDSA)2016年《念珠菌感染临床实践指南》、2010年《隐球菌感染临床实践指南》、2008年《曲霉菌感染临床实践指南》、2014年欧洲临床微生物与感染性疾病学会《实体器官移植受者中侵袭性

中华医学会器官移植学分会和中国医师协会器官移植医师分会结合更新的国内外临床证据,并参考2013年中国侵袭性真菌感染工作组的《血液病/恶性肿瘤患者侵袭性真菌病的诊断标准与治疗原则(第四次修订版)》、美国感染学会(IDSA)2016年《念珠菌感染临床实践指南》、2010年《隐球菌感染临床实践指南》、2008年《曲霉菌感染临床实践指南》、2014年欧洲临床微生物与感染性疾病学会《实体器官移植受者中侵袭性真菌感染》、2008年欧洲癌症研究和治疗组织侵袭性真菌感染协作组/美国国立变态反应和感染病研究院真菌病研究组(EORTC/MSG)《侵袭性真菌病修订定义》等文件,对2009年版《实体器官移植患者侵袭性真菌感染的诊断和治疗指南》进行修订,以期为实体器官移植和相关学科的同道提供帮助。


在本版指南中,“侵袭性真菌病”的概念代替了此前的“侵袭性真菌感染(invasive fungal infection,IFI)”。“感染”着重描述的是病原菌与宿主的一种共存状态,而“病”则描述的是病原菌在体内侵袭、繁殖造成器官组织损伤的病理现象,更能反映一种病理状态。


侵袭性真菌病(invasive fungal disease,IFD)是指真菌侵入人体,在组织、器官或血液中生长、繁殖,并导致炎症反应及组织损伤的疾病。在实体器官移植(solid organ trans—plant,SOT)受者中,IFD已成为致病和死亡的重要原因。


2009年,中华医学会器官移植学分会结合我国移植受者的临床特点,参考国内外相关指南,制订了《实体器官移植患者侵袭性真菌感染的诊断和治疗指南》。


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    2016-11-21 zhaojie88
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    2016-11-21 sunyl07
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