J Glaucoma:假性剥脱性青光眼与原发性开角型青光眼的眼周围血管密度比较研究

2018-08-27 MedSci MedSci原创

韩国首尔大学医学院眼科的Park JH和Yoo C近日在J Glaucoma发表了一篇文章,他们比较了假性剥脱性青光眼(PXG)与原发性开角型青光眼(POAG)之间的毛细血管周围血管密度。

韩国首尔大学医学院眼科的Park JH和Yoo C近日在J Glaucoma发表了一篇文章,他们比较了假性剥脱性青光眼(PXG)与原发性开角型青光眼(POAG)之间的毛细血管周围血管密度。

他们使用光学相干断层扫描血管造影术(OCTA)评估桡动脉周围毛细血管(RPC)中的毛细血管周围血管密度,并比较PXG患者和年龄相匹配POAG患者的平均偏差(MD)。在视盘边缘和视盘边缘750mm之间测量血管密度。

他们总共研究了39只PXG眼睛和与之想匹配的39只POAG眼睛。PXG组平均未治疗眼压高于POAG组(21.4±6.7±mm Hg对14.9±2.9; P <0.001),但在年龄、屈光不正、视野MD或视网膜神经纤维层(RNFL)厚度等,两组之间没有显着性。然而,在PXG患者眼中,RPC的平均周围血管密度低于POAG的眼睛。此外,在毛细血管周围血管密度与视野MD和RNFL厚度之间存在显着相关性。

因此,他们认为,PXG眼周围毛细血管血管密度显着低于严重程度相似的POAG患者。

原文出处:

Park, J.H., et al., Peripapillary Vessel Density in Glaucomatous Eyes: Comparison between Pseudoexfoliation Glaucoma and Primary Open-angle Glaucoma. J Glaucoma, 2018.

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    2018-10-14 aliceclz
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