Anticancer Research:5-FU+顺铂改善晚期胃癌患者预后

2012-07-30 小康 医学论坛网

     《抗癌研究》(Anticancer Research)杂志近期发表的一项研究提示,5-氟尿嘧啶(5-FU)联合顺铂可改善晚期或复发性胃癌患者预后。   该研究是一项Ⅱ期研究,在26例晚期或复发性胃癌患者中评估了5-FU联合顺铂的效果和安全性。治疗方案包括,连续5天静脉输注顺铂3.3 mg/m2/天,连续4周每隔1天(第1、3、5天)持续静脉输注5-FU 

  

  《抗癌研究》(Anticancer Research)杂志近期发表的一项研究提示,5-氟尿嘧啶(5-FU)联合顺铂可改善晚期或复发性胃癌患者预后。

  该研究是一项Ⅱ期研究,在26例晚期或复发性胃癌患者中评估了5-FU联合顺铂的效果和安全性。治疗方案包括,连续5天静脉输注顺铂3.3 mg/m2/天,连续4周每隔1天(第1、3、5天)持续静脉输注5-FU 300~500 mg。

  结果显示,部分缓解率为34.6%。中位生存期为12.8个月,1年生存率为53.1%。不良反应轻。

  相关链接:AKIHITO ENJOJI,JUNICHIRO FURUI,YASUHIRO NAGATA,HIKARU FUJIOKA, TOSHIAKI SHIOGAMA,AKIMI MIYATA,HIROKI KISHIKAWA,SHIGETOSHI MATSUO,TORU IWATA, TAKASHI KANEMATSU, SUSUMU EGUCHI.Effects of Intermittent 5-Fluorouracil and Low-dose Cisplatin Therapy on Advanced and Recurrent Gastric Cancer.June 27, 2012


    

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    2012-08-01 yangshch