Addict Biol:研究人员发现荷尔蒙增加鼠的性冲动

2015-02-03 MedSci MedSci原创

瑞典的研究表明,老鼠接受补充“食欲激素“--胃饥饿素能增加它们的性活动。这种激素是否对人类具有相同的影响目前是未知的,但如果是这样,研究人员可能已经发现未来治疗性虐待的关键因素。 胃饥饿素是一种胃肠激素,从胃里释放,通过激活大脑的奖励系统参与食欲的刺激。因为大脑的奖励系统也促使我们寻求伴侣做爱,萨尔格学院的一个研究小组决定研究是否饥饿激素也可能影响性行为。 确认效果 答案是:是的,至少在老鼠

瑞典的研究表明,老鼠接受补充“食欲激素“--胃饥饿素能增加它们的性活动。这种激素是否对人类具有相同的影响目前是未知的,但如果是这样,研究人员可能已经发现未来治疗性虐待的关键因素。

胃饥饿素是一种胃肠激素,从胃里释放,通过激活大脑的奖励系统参与食欲的刺激。因为大脑的奖励系统也促使我们寻求伴侣做爱,萨尔格学院的一个研究小组决定研究是否饥饿激素也可能影响性行为。

确认效果

答案是:是的,至少在老鼠。

在这项研究中,研究人员表明,当老鼠接受补充激素, 就努力找另一半,增加它们的性活动。效果的确认是在后续实验中,小鼠接受胃饥饿素抑制剂,取而代之的是减少它们的性活动。

“这是已知的,胃饥饿素影响奖励系统,而这个机制又由食物,酒精和其他成瘾药物引发。现在我们的研究首次表明,胃饥饿素在自然的奖励机制中也扮演了重要的角色,如性,”萨尔格学院研究员Elisabet Jerlhag说。


还需要更多的研究

研究表明, 胃饥饿素的影响通过多巴胺传递, 在大脑的奖励系统中这是一个已知的重要信使。研究人员的结论是,胃饥饿素和多巴胺均调节正常小鼠的性行为。

“然而,这并不意味着饥饿激素对人类也有相同的功能。该发现仍需要更多的研究。但胃饥饿素抑制剂可能是一个未来治疗性瘾和性虐待的关键,”Elisabet Jerlhag说:“成瘾行为,包括性虐待是我们的重大社会问题,新的治疗策略很有必要性。希望我们的结果为这项工作的难点提供部分解决方案,”Elisbet Jerlhag说。

原始出处

Egecioglu E1, Prieto-Garcia L, Studer E, Westberg L, Jerlhag E.The role of ghrelin signalling for sexual behaviour in male mice.Addict Biol. 2014 Dec 4.

本文是MedSci编译,欢迎转发,转发请注明出处,非常感谢!

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    2015-06-19 jeanqiuqiu
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    2015-07-16 sunylz
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