JAMA Dermatol:黑色素瘤筛查时,肛周痣也不能放过

2016-07-12 Seven L 译 MedSci原创

近期发表在JAMA Dermatology的研究称,进行黑色素瘤的筛查和监测的患者,还应该对肛周区黑色素细胞痣进行筛查。伊利诺斯大学的Ava Socik及其同事分析了236名患者的数据,其中包括非西班牙裔白人(N = 219)、西班牙裔白人(N = 4)和非白人(n = 13)患者。患者们均进行黑色素瘤或皮肤癌的评估。年龄在23-84岁,男女各占138和98名。研究人员发现,48.9%的非西班牙裔

近期发表在JAMA Dermatology的研究称,进行黑色素瘤的筛查和监测的患者,还应该对肛周区黑色素细胞痣进行筛查。

伊利诺斯大学的Ava Socik及其同事分析了236名患者的数据,其中包括非西班牙裔白人(N = 219)、西班牙裔白人(N = 4)和非白人(n = 13)患者。患者们均进行黑色素瘤或皮肤癌的评估。年龄在23-84岁,男女各占138和98名。

研究人员发现,48.9%的非西班牙裔白人其肛周有痣(任何尺寸);39.7%的肛周有直径至少2 mm的痣,还有5.5%的肛周有直径至少5 mm的痣。西班牙裔白人患者中,50%的有肛周痣,但没有直径≥2 mm的肛周痣。非白人中38.5%的有直径≥2 mm的肛周痣,但没有直径5 mm以上的肛周痣。

分析表明,非西班牙裔白人中,肛周痣和非典型痣切除史之间有明显的相关性(OR = 2.9; 95% CI, 1.5-5.7);与肛周痣相关的其他因素包括现存的非典型痣 (OR = 2.2; 95% CI, 1.3–3.9)、非典型痣模式(OR = 2; 95% CI, 1.2-3.6)、直径≥2 mm的痣有20个或更多,直径≥5 mm的痣至少有5个(OR = 1.8; 95% CI, 1.1–3.1)、至少4个直径5mm以上的非典型痣(OR = 1.9; 95% CI, 1.1 – 3.3)。

据此,研究者认为,进行黑色素瘤的筛查和监测的患者,还应该对肛周区黑色素细胞痣进行筛查,因为这和身体其他部位的非典型痣有关。

原始出处:


Socik A, et al. Prevalence and Gross Morphologic Features of Perianal Melanocytic Nevi.JAMA Dermatol. 2016;doi:10.1001/jamadermatol.2016.1885.

Perianal area examination may aid in identifying atypical nevi during melanoma screening.Healio.July 11, 2016

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    2017-06-20 sunylz
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    2017-06-05 zxxiang
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    2016-07-14 yese
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