Radiology：无创低温消融方式--机器人登场啦！

2018-06-08 shaosai MedSci原创

本研究旨在确定采用机器人辅助声波治疗 (RAST)，即一种基于组织摧毁术的无创低温聚焦超声治疗方法来进行临床上相关的肝脏消融 (即治疗2厘米肝肿瘤的消融区) 的可行性。

本研究旨在确定采用机器人辅助声波治疗 (RAST)，即一种基于组织摧毁术的无创低温聚焦超声治疗方法来进行临床上相关的肝脏消融 (即治疗2厘米肝肿瘤的消融区) 的可行性。

本研究得到了动物使用和护理机构委员会的批准。使用RAST对十只雌性猪的单个指定的3厘米球形治疗区进行治疗，并立即进行腹部磁共振 (MR) 成像。三头猪 (急性组) 在 mr 成像后死亡。七只猪 (慢性组) 生存了约4星期并且在死亡前又进行了MR扫描。动物进行了尸检及采集肝脏进行消融区的组织学评估。RAST消融用700赫治疗传感器进行。使用学生 t 试验，比较预计的与达到的消融直径，球形的差异，以及消融区体积从急性到慢性成像的变化。

结果为消融区的球形指数为 0.99±0.01 (标准差) (P. 001 vs 球形指数 1)。前后和横向径与预计值的差异不显着 (分别为3.4 ±0.7；P = 0.08 和 3.2±0.8；P = 0.29， )。上下径明显大于预计值(3.8 ±1.1；P =0. 04)，可能是由于呼吸运动。中央消融区显示出细胞完全破坏和部分坏死区。纤维环可包围消融区4周。4周随访图像显示消融区体积可减少 64% (P＜0.001）。

本研究说明RAST可以以一种无创方式在猪模型中进行临床相关消融。

原始出处：

Smolock AR， Cristescu MM， Vlaisavljevich E. et al.Robotically Assisted Sonic Therapy as a Noninvasive Nonthermal Ablation Modality： Proof of Concept in a Porcine Liver Model.Radiology.DOI：10.1148/radiol.2018171544

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2018-06-09 xue8602

#机器人#

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2018-06-09 xiangyuzhou972

#消融#

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2018-06-09 zhaojie88

#机器#

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2018-06-08 1209e435m98(暂无昵称)

学习了.谢谢分享

79 0
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2018-06-08 三生有幸9135

学习一下谢谢

62 0
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2018-06-08 飛歌

厉害了我的哥

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