Int J Mol Sci:ω3脂肪酸可用于辅助治疗炎症性肠病

2020-09-28 MedSci原创 MedSci原创

炎症性肠病(IBD)是影响胃肠道的慢性炎症过程,主要以溃疡性结肠炎(UC)和克罗恩病(CD)为代表。ω3脂肪酸(二十碳五烯酸和二十二碳六烯酸)在炎症过程中显示出不可或缺的作用,基于这些原因

炎症性肠病(IBD)是影响胃肠道的慢性炎症过程,主要以溃疡性结肠炎(UC)和克罗恩病(CD)为代表。ω3脂肪酸(二十碳五烯酸和二十二碳六烯酸)在炎症过程中显示出不可或缺的作用,基于这些原因,本研究旨在回顾这些酸对UC和CD的影响,研究结果已在线发表于Int J Mol Sci。

研究人员对PUMED和EMBASE等数据库进行了检索,最终选择了15项符合纳入标准的研究。结果显示,ω3脂肪酸可减轻UC患者的肠道炎症,诱导并维持临床缓解,并与CD患者减少促炎细胞因子、降低疾病活性、提高生活质量有关。此外,食用这些脂肪酸可能与降低患IBD的风险有关。

许多研究表明ω3作为辅助治疗或预防UC或CD的有益作用。然而,大多数研究都是针对少数患者进行的,而且在食用方式、食物类型或使用的配方类型上存在许多差异。所有这些因素都会对结果造成很大干扰,无法进行可靠的比较。

 

原始出处:

 

Ledyane Taynara MartonRicardo de Alvares Goulart, et al., Omega Fatty Acids and Inflammatory Bowel Diseases: An Overview. Int J Mol Sci. 2019 Sep 30;20(19):4851. doi: 10.3390/ijms20194851.

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    2020-10-12 ms9000001531324985

    能把研究用于日常就好了,预防疾病

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1779175, encodeId=1e3b1e791755c, content=<a href='/topic/show?id=2216130401' target=_blank style='color:#2F92EE;'>#3脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1304, encryptionId=2216130401, topicName=3脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=416347, createdName=mhzhuang@stu.e, createdTime=Tue Dec 01 16:05:09 CST 2020, time=2020-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1778799, encodeId=31351e78799c1, content=<a href='/topic/show?id=2216130401' target=_blank style='color:#2F92EE;'>#3脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1304, encryptionId=2216130401, topicName=3脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=416347, createdName=mhzhuang@stu.e, createdTime=Sun Aug 22 18:05:09 CST 2021, time=2021-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=891411, encodeId=8634891411ab, content=能把研究用于日常就好了,预防疾病, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200923/8af58a8d80fa4d3e83e7cc9686930f6e/4638f64094bd40a4bb51a09cacaee275.jpg, createdBy=33335378595, createdName=ms9000001531324985, createdTime=Mon Oct 12 09:57:51 CST 2020, time=2020-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=889478, encodeId=1d218894e86c, content=很好的文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6d30104504, createdName=cmuwisdom, createdTime=Wed Sep 30 20:00:26 CST 2020, time=2020-09-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1547379, encodeId=09ca154e37921, content=<a href='/topic/show?id=4ef26e01766' target=_blank style='color:#2F92EE;'>#炎症性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67017, encryptionId=4ef26e01766, topicName=炎症性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=09e813968720, createdName=12498dd9m15暂无昵称, createdTime=Wed Sep 30 06:05:09 CST 2020, time=2020-09-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=888967, encodeId=022188896ee0, content=ω3不仅可能与降低IBD有关,平常饮食多摄入也有益于身体健康。, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220301/6252e946e5ef413b86dc0f7d1f73b6db/9a7e8c88a38e487b8da4968a67bbd261.png, createdBy=b9f692910, createdName=rayms, createdTime=Mon Sep 28 18:24:50 CST 2020, time=2020-09-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=888944, encodeId=8618888944de, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200826/93863e99dbdd47b7a8de6d0464a61901/e0c652961ab447f7aab5d63c6958a527.jpg, createdBy=28335287925, createdName=不想取名, createdTime=Mon Sep 28 16:37:27 CST 2020, time=2020-09-28, status=1, ipAttribution=)]
    2020-09-30 cmuwisdom

    很好的文章

    0

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    2020-09-28 rayms

    ω3不仅可能与降低IBD有关,平常饮食多摄入也有益于身体健康。

    0

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    2020-09-28 不想取名

    谢谢分享

    0