Radiology:双源CT衍生碘图在评价胸膜癌的价值

2019-08-05 shaosai MedSci原创

本研究旨在评价光谱CT在鉴别非钙化性良性胸膜病变与胸膜癌的价值。

本研究旨在评价光谱CT在鉴别非钙化性良性胸膜病变与胸膜癌的价值。

本研究回顾性分析了有经组织病理学和或影像学确诊的非钙化胸膜病变且行对比增强静脉晚期光谱CT检查患者的资料。利用增强光谱胸部CT图像进行常规图像、碘剂叠加(IO)图像和虚拟单色图像进行重建。由4名放射科医生评价有无病变、病变密度和诊断确定性。测量常规图像和IO图像CT值。利用ROC曲线得到鉴别良恶性病变的最佳截断值。

本研究共纳入了84例胸膜病变患者。IC  ROC曲线下面积要显着大于常规图像CT值。最佳IC截断值为1.3 mg/mL。光谱重建与常规CT图像检查胸膜癌的敏感性分别为96% (199 / 208)、83% (172 / 208),特异性分别为84% (161 / 192)、63% (120 / 192) (P ≤ .001)。

本研究表明,与常规图像相比,光谱CT联合碘剂图能够定性、定量提高鉴别非钙化性胸膜良性病变与胸膜癌的价值。

原始出处:

Lennartz S, Le Blanc M, Zopfs D,et al.Dual-Energy CT-derived Iodine Maps: Use in Assessing Pleural Carcinomatosis.Radiology.DOI:10.1148/radiol.2018181567

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    2020-03-04 lifestar
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    2019-08-07 huagfeg