Neurology:脊髓灌注压与脊髓损伤后神经功能预后

2017-09-17 zhangfan MedSci原创

研究证实,脊髓灌注压维持在50 mm Hg以上是脊髓损伤后神经功能恢复的强预测因子,脊髓灌注压可以为急性脊髓损伤患者的血流动力学治疗提供关键信息

近日研究人员考察了腰鞘内导管测量的脊髓灌注压(SCPP)与传统的的平均动脉压(MAP)对脊髓损伤后神经系统预后结果预测的差异。

研究招募了92名急性脊髓损伤患者。在外伤后的第1周对患者进行MAP、SCPP以及脑脊液压(CSFP)监测,在外伤后以及6个月进行神经功能缺损情况评估。研究人员通过逻辑回归、相对风险系统迭代和Cox比例风险模型考察与神经系统结果相关的血流动力学模式。

研究发现脊髓灌注压是独立的阳性神经功能恢复因子(OR, 1.039, p = 0.002)。若患者的SCPP低于50mmHg,其神经功能不良预后的相对危险不断增加;对于神经系统分级改善的患者,SCPP低于50mmHg的次数显著少于未改善患者(p = 0.012);对于SCPP持续低于50 mm Hg的患者,治疗后神经系统分级改善的可能性较低(p = 0.0056)。对于MAP或CSFP未发现上述现象。。

研究证实,脊髓灌注压维持在50 mm Hg以上是脊髓损伤后神经功能恢复的强预测因子,脊髓灌注压可以为急性脊髓损伤患者的血流动力学治疗提供关键信息。

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    2017-11-12 yinhl1978
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    2017-09-26 心愿

    脊髓灌注压可以为急性脊髓损伤患者的血流动力学治疗提供关键信息

    0

  3. 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    2017-09-19 1e10c84am36(暂无匿称)

    文章很好.值得分享

    0

  4. 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  6. 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  7. 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createdTime=Mon Sep 18 06:28:19 CST 2017, time=2017-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=245017, encodeId=0d2324501e2c, content=很好的文章.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Sun Sep 17 12:44:38 CST 2017, time=2017-09-17, status=1, ipAttribution=)]
    2017-09-18 一个字-牛

    学习了谢谢分享

    0

  8. 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attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eoNX3lUOlDKGBUEPNwZx0nibmdcFyeibnX4WMhUSCU2REpGRWtSmnT2CCs0dA5waxvJknYDxwtYnIcQ/132, createdBy=294e2500218, createdName=ms3046638856685384, createdTime=Tue Sep 19 00:27:00 CST 2017, time=2017-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1422062, encodeId=e5941422062eb, content=<a href='/topic/show?id=e5f0e42224f' target=_blank style='color:#2F92EE;'>#神经功能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74222, encryptionId=e5f0e42224f, topicName=神经功能)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=85503680375, createdName=lhlxtx, createdTime=Tue Sep 19 00:27:00 CST 2017, time=2017-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1492847, encodeId=01eb149284e23, content=<a 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    2017-09-18 baihao215

    科学严谨的态度.学习了

    0

  9. 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createdTime=Mon Sep 18 06:28:19 CST 2017, time=2017-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=245017, encodeId=0d2324501e2c, content=很好的文章.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Sun Sep 17 12:44:38 CST 2017, time=2017-09-17, status=1, ipAttribution=)]
    2017-09-18 三生有幸9135

    学习一下谢谢分享

    0

  10. 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GetPortalCommentsPageByObjectIdResponse(id=245237, encodeId=c03d24523eac, content=科学严谨的态度.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCclExeQ6LOGMD4dTsia4Ty4HtZCxRmG5vO5XIKfKX3a3vusfhHSej4Iib517vmhFW7RQgh7bpDp1yw/0, createdBy=50951609779, createdName=baihao215, createdTime=Mon Sep 18 07:56:07 CST 2017, time=2017-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=245187, encodeId=574a24518e5e, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Mon Sep 18 06:28:19 CST 2017, time=2017-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=245017, encodeId=0d2324501e2c, content=很好的文章.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Sun Sep 17 12:44:38 CST 2017, time=2017-09-17, status=1, ipAttribution=)]
    2017-09-17 清风拂面

    很好的文章.谢谢分享

    0

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