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Neuroradiology：原发性书写震颤患者脑网络的变化

2017-09-07 shaosai MedSci原创

原发性书写震颤脑网络聚类分析
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原发性书写震颤（PWT）是一种少见的特定任务型震颤，症状仅在书写时或在书写过程中调整手部姿势时发生。PWT的病理生理学机制尚不清楚。本研究旨在利用基于图论的聚类分析探索PWT患者静息态功能脑连接的变化，并将结果发表在Neuroradiology上。

原发性书写震颤（PWT）是一种少见的特定任务型震颤，症状仅在书写时或在书写过程中调整手部姿势时发生。PWT的病理生理学机制尚不清楚。本研究旨在利用基于图论的聚类分析探索PWT患者静息态功能脑连接的变化，并将结果发表在Neuroradiology上。

本前瞻性病例对照研究共纳入了10PWT患者和10名年龄、性别相匹配的健康志愿者，并行3T MRI扫描。利用基于图论的聚类分析比较病例组和对照组小世界功能脑网络的参数。

在病例组和对照组间年龄、左右利手（均为右利手）、性别（均为男性）和MMSE评分间并无统计学差异。出现震颤表现的平均年龄为51.7 ± 8.6岁，震颤长达3.5 ± 1.9年。基于图论的聚类分析发现PWT患者与对照组相比具有较低的聚类系数和更高的路径长度，这表明小世界脑结构发生改变。PWI患者双侧小脑半球内侧、右侧背外侧前额叶皮层（DLPFC）和左侧后顶叶皮层（PPC）的聚类系数减低。

本研究表明，PWI患者小世界脑网络连接在双侧小脑半球内侧、右侧DLPFC和左侧PPC发生了变化。

原始出处：

Lenka A， Jhunjhunwala KR， Panda R， et al，Altered brain network measures in patients with primary writing tremor.Neuroradiology. 2017.DOI： 10.1007/s00234-017-1895-y

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    2017-09-14 jiyangfei

    #原发性#

    0

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    2017-09-25 ms7421025882867189

    #脑网络#

    0

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    2017-09-09 1e0ece0dm09(暂无匿称)

    谢谢分享

    0

  4. 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encryptionId=41d698891ef, topicName=震颤)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=59428697908, createdName=kalseyzl, createdTime=Sat Sep 09 14:05:00 CST 2017, time=2017-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241836, encodeId=7cb5241836d0, content=图论, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/2Wn9yHJT3F9YAmOYUBrvtHPhbqxGuRTFGunTBSOrZJw5pC9prNS1jgibpOicLUUXk2gTPYy13caXdTickob5s6OqA/132, createdBy=16902144520, createdName=158****3960, createdTime=Fri Sep 08 19:55:06 CST 2017, time=2017-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241693, encodeId=23f52416933e, content=好好学习.涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLANEL7Sww3HicKsN9aribicAmGGWXOIMEiaZ1iadgZg9RibjqSwIKUS8gSPib2NwTVg2zVvVJhdP3BkuDIl/0, createdBy=944d1605392, createdName=shaosai, createdTime=Fri Sep 08 09:32:29 CST 2017, time=2017-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241660, encodeId=5bd8241660ae, content=好好看下.内容丰富, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Fri Sep 08 07:52:52 CST 2017, time=2017-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241656, encodeId=aa04241656cf, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, 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createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Fri Sep 08 07:01:26 CST 2017, time=2017-09-08, status=1, ipAttribution=)]
    2017-09-09 kalseyzl

    #震颤#

    0

  5. 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLANEL7Sww3HicKsN9aribicAmGGWXOIMEiaZ1iadgZg9RibjqSwIKUS8gSPib2NwTVg2zVvVJhdP3BkuDIl/0, createdBy=944d1605392, createdName=shaosai, createdTime=Fri Sep 08 09:32:29 CST 2017, time=2017-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241660, encodeId=5bd8241660ae, content=好好看下.内容丰富, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Fri Sep 08 07:52:52 CST 2017, time=2017-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241656, encodeId=aa04241656cf, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, 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createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Fri Sep 08 07:01:26 CST 2017, time=2017-09-08, status=1, ipAttribution=)]
    2017-09-08 158****3960

    图论

    0

  6. 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLANEL7Sww3HicKsN9aribicAmGGWXOIMEiaZ1iadgZg9RibjqSwIKUS8gSPib2NwTVg2zVvVJhdP3BkuDIl/0, createdBy=944d1605392, createdName=shaosai, createdTime=Fri Sep 08 09:32:29 CST 2017, time=2017-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241660, encodeId=5bd8241660ae, content=好好看下.内容丰富, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Fri Sep 08 07:52:52 CST 2017, time=2017-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241656, encodeId=aa04241656cf, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, 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createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Fri Sep 08 07:01:26 CST 2017, time=2017-09-08, status=1, ipAttribution=)]
    2017-09-08 shaosai

    好好学习.涨知识

    0

  7. 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encryptionId=41d698891ef, topicName=震颤)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=59428697908, createdName=kalseyzl, createdTime=Sat Sep 09 14:05:00 CST 2017, time=2017-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241836, encodeId=7cb5241836d0, content=图论, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/2Wn9yHJT3F9YAmOYUBrvtHPhbqxGuRTFGunTBSOrZJw5pC9prNS1jgibpOicLUUXk2gTPYy13caXdTickob5s6OqA/132, createdBy=16902144520, createdName=158****3960, createdTime=Fri Sep 08 19:55:06 CST 2017, time=2017-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241693, encodeId=23f52416933e, content=好好学习.涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLANEL7Sww3HicKsN9aribicAmGGWXOIMEiaZ1iadgZg9RibjqSwIKUS8gSPib2NwTVg2zVvVJhdP3BkuDIl/0, createdBy=944d1605392, createdName=shaosai, createdTime=Fri Sep 08 09:32:29 CST 2017, time=2017-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241660, encodeId=5bd8241660ae, content=好好看下.内容丰富, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Fri Sep 08 07:52:52 CST 2017, time=2017-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241656, encodeId=aa04241656cf, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=445f1740270, createdName=meiliwuxian, createdTime=Fri Sep 08 07:49:11 CST 2017, time=2017-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241642, encodeId=8a12241642f0, content=涨知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Fri Sep 08 07:18:56 CST 2017, time=2017-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241624, encodeId=f918241624d3, content=谢谢分享.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Fri Sep 08 07:01:26 CST 2017, time=2017-09-08, status=1, ipAttribution=)]
    2017-09-08 忠诚向上

    好好看下.内容丰富

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1846589, encodeId=2d7d18465892f, content=<a href='/topic/show?id=d3a33e0306d' target=_blank style='color:#2F92EE;'>#原发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37030, encryptionId=d3a33e0306d, topicName=原发性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8e4c53, createdName=jiyangfei, createdTime=Thu Sep 14 22:05:00 CST 2017, time=2017-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1740337, encodeId=198c1e4033773, content=<a href='/topic/show?id=5c73850113b' target=_blank style='color:#2F92EE;'>#脑网络#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85011, encryptionId=5c73850113b, topicName=脑网络)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b0d34733187, createdName=ms7421025882867189, createdTime=Mon Sep 25 01:05:00 CST 2017, time=2017-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242219, encodeId=da28242219ae, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Sat Sep 09 16:34:21 CST 2017, time=2017-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1490127, encodeId=6bd3149012ef3, content=<a href='/topic/show?id=41d698891ef' target=_blank style='color:#2F92EE;'>#震颤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98891, encryptionId=41d698891ef, topicName=震颤)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=59428697908, createdName=kalseyzl, createdTime=Sat Sep 09 14:05:00 CST 2017, time=2017-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241836, encodeId=7cb5241836d0, content=图论, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/2Wn9yHJT3F9YAmOYUBrvtHPhbqxGuRTFGunTBSOrZJw5pC9prNS1jgibpOicLUUXk2gTPYy13caXdTickob5s6OqA/132, createdBy=16902144520, createdName=158****3960, createdTime=Fri Sep 08 19:55:06 CST 2017, time=2017-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241693, encodeId=23f52416933e, content=好好学习.涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLANEL7Sww3HicKsN9aribicAmGGWXOIMEiaZ1iadgZg9RibjqSwIKUS8gSPib2NwTVg2zVvVJhdP3BkuDIl/0, createdBy=944d1605392, createdName=shaosai, createdTime=Fri Sep 08 09:32:29 CST 2017, time=2017-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241660, encodeId=5bd8241660ae, content=好好看下.内容丰富, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Fri Sep 08 07:52:52 CST 2017, time=2017-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241656, encodeId=aa04241656cf, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=445f1740270, createdName=meiliwuxian, createdTime=Fri Sep 08 07:49:11 CST 2017, time=2017-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241642, encodeId=8a12241642f0, content=涨知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Fri Sep 08 07:18:56 CST 2017, time=2017-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241624, encodeId=f918241624d3, content=谢谢分享.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Fri Sep 08 07:01:26 CST 2017, time=2017-09-08, status=1, ipAttribution=)]
    2017-09-08 meiliwuxian

    学习了

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1846589, encodeId=2d7d18465892f, content=<a href='/topic/show?id=d3a33e0306d' target=_blank style='color:#2F92EE;'>#原发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37030, encryptionId=d3a33e0306d, topicName=原发性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8e4c53, createdName=jiyangfei, createdTime=Thu Sep 14 22:05:00 CST 2017, time=2017-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1740337, encodeId=198c1e4033773, content=<a href='/topic/show?id=5c73850113b' target=_blank style='color:#2F92EE;'>#脑网络#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85011, encryptionId=5c73850113b, topicName=脑网络)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b0d34733187, 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encryptionId=41d698891ef, topicName=震颤)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=59428697908, createdName=kalseyzl, createdTime=Sat Sep 09 14:05:00 CST 2017, time=2017-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241836, encodeId=7cb5241836d0, content=图论, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/2Wn9yHJT3F9YAmOYUBrvtHPhbqxGuRTFGunTBSOrZJw5pC9prNS1jgibpOicLUUXk2gTPYy13caXdTickob5s6OqA/132, createdBy=16902144520, createdName=158****3960, createdTime=Fri Sep 08 19:55:06 CST 2017, time=2017-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241693, encodeId=23f52416933e, content=好好学习.涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLANEL7Sww3HicKsN9aribicAmGGWXOIMEiaZ1iadgZg9RibjqSwIKUS8gSPib2NwTVg2zVvVJhdP3BkuDIl/0, createdBy=944d1605392, createdName=shaosai, createdTime=Fri Sep 08 09:32:29 CST 2017, time=2017-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241660, encodeId=5bd8241660ae, content=好好看下.内容丰富, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Fri Sep 08 07:52:52 CST 2017, time=2017-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241656, encodeId=aa04241656cf, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=445f1740270, createdName=meiliwuxian, createdTime=Fri Sep 08 07:49:11 CST 2017, time=2017-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241642, encodeId=8a12241642f0, content=涨知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Fri Sep 08 07:18:56 CST 2017, time=2017-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241624, encodeId=f918241624d3, content=谢谢分享.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Fri Sep 08 07:01:26 CST 2017, time=2017-09-08, status=1, ipAttribution=)]
    2017-09-08 榄枷檬

    涨知识了

    0

  10. [GetPortalCommentsPageByObjectIdResponse(id=1846589, encodeId=2d7d18465892f, content=<a href='/topic/show?id=d3a33e0306d' target=_blank style='color:#2F92EE;'>#原发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37030, encryptionId=d3a33e0306d, topicName=原发性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8e4c53, createdName=jiyangfei, createdTime=Thu Sep 14 22:05:00 CST 2017, time=2017-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1740337, encodeId=198c1e4033773, content=<a href='/topic/show?id=5c73850113b' target=_blank style='color:#2F92EE;'>#脑网络#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85011, encryptionId=5c73850113b, topicName=脑网络)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b0d34733187, 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encryptionId=41d698891ef, topicName=震颤)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=59428697908, createdName=kalseyzl, createdTime=Sat Sep 09 14:05:00 CST 2017, time=2017-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241836, encodeId=7cb5241836d0, content=图论, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/2Wn9yHJT3F9YAmOYUBrvtHPhbqxGuRTFGunTBSOrZJw5pC9prNS1jgibpOicLUUXk2gTPYy13caXdTickob5s6OqA/132, createdBy=16902144520, createdName=158****3960, createdTime=Fri Sep 08 19:55:06 CST 2017, time=2017-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241693, encodeId=23f52416933e, content=好好学习.涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLANEL7Sww3HicKsN9aribicAmGGWXOIMEiaZ1iadgZg9RibjqSwIKUS8gSPib2NwTVg2zVvVJhdP3BkuDIl/0, createdBy=944d1605392, createdName=shaosai, createdTime=Fri Sep 08 09:32:29 CST 2017, time=2017-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241660, encodeId=5bd8241660ae, content=好好看下.内容丰富, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Fri Sep 08 07:52:52 CST 2017, time=2017-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241656, encodeId=aa04241656cf, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=445f1740270, createdName=meiliwuxian, createdTime=Fri Sep 08 07:49:11 CST 2017, time=2017-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241642, encodeId=8a12241642f0, content=涨知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Fri Sep 08 07:18:56 CST 2017, time=2017-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241624, encodeId=f918241624d3, content=谢谢分享.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Fri Sep 08 07:01:26 CST 2017, time=2017-09-08, status=1, ipAttribution=)]
    2017-09-08 明月清辉

    谢谢分享.学习了

    0

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