Pathol Oncol Res:蓝莓提取物是癌症治疗的强大“助推剂”!

2017-12-31 MedSci译 medicalxpress

根据美国疾病控制和预防中心的资料,美国每年约有12,000名妇女被诊断为宫颈癌。宫颈癌最常见的治疗方法之一就是放疗。放射疗法破坏癌细胞,同时也破坏附近的健康细胞。密苏里大学医学院的研究人员研究人体癌细胞体外研究表明,将蓝莓提取物与辐射相结合可以提高治疗效果。

根据美国疾病控制和预防中心的资料,美国每年约有12,000名妇女被诊断为宫颈癌。宫颈癌最常见的治疗方法之一就是放疗。放射疗法破坏癌细胞,同时也破坏附近的健康细胞。密苏里大学医学院的研究人员研究人体癌细胞体外研究表明,将蓝莓提取物与辐射相结合可以提高治疗效果。

“放射治疗使用高能X射线和其他粒子,如伽马射线来摧毁癌细胞。”MU医学院客座教授,Yujiang Fang博士说道。 “对于某些癌症,如晚期宫颈癌,放疗是一种很好的治疗选择,但是对健康细胞的附带损伤总是会发生,基于以前的研究,我们研究了蓝莓提取物,以证实它可以用作放射增敏剂。”

放射增敏剂是使癌细胞对放射治疗更敏感的无毒化学物质。在以前的研究中,方和他的研究小组表明白藜芦醇是红葡萄中的一种化合物,可以用作治疗前列腺癌的放射增敏剂。蓝莓也含有白藜芦醇。

“除了白藜芦醇之外,蓝莓还含有类黄酮。”方先生说。他也是爱荷华州得梅因大学的学术病理学家,微生物学和免疫学助理教授。 “黄酮类化合物可能具有抗氧化,抗炎和抗菌特性。”

研究人员使用人类宫颈癌细胞系来模拟临床治疗。将细胞系分成四组,包括对照组,仅接受辐射的组,仅接受蓝莓提取物的组,以及接受辐射和提取物的组。

方说:“我们的团队使用了三种不同的方法来确认研究结果。 “辐射使癌细胞减少了大约20%,有趣的是,仅接受蓝莓提取物的细胞组癌细胞减少了25%,而放射和提取组的细胞减少最多,减少了约70%”。

方解释说,使蓝莓提取放射增敏剂的机制也减少了细胞生长的异常爆炸。

Fang说:“癌细胞通过重塑来避免死亡。” “随着细胞增殖的减少,这种提取物也会”诱骗“癌细胞死亡,所以它会抑制癌细胞的诞生并促进癌细胞的死亡。”

方说,动物研究是下一步,以确认他的团队可以取得同样的结果。

方说:“蓝莓很普遍,遍布世界各地。 “它们容易获得,价格便宜,作为提高现有治疗效果的自然疗法选择,我感到他们会被热烈接受。”

“蓝莓作为治疗子宫颈癌的潜在放射敏感剂”研究最近在“病理学和肿瘤学”杂志上发表。

原始出处:

Kristoffer T. DavidsonZiwen ZhuDean Balabanov, et.al. Beyond Conventional Medicine - a Look at Blueberry, a Cancer-Fighting Superfruit.  Pathology and Oncology Research

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    2018-02-23 minlingfeng
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    2018-07-08 docwu2019
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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Sun Dec 31 13:37:17 CST 2017, time=2017-12-31, status=1, ipAttribution=)]
    2018-01-02 半夏微凉

    阅读了谢谢分享

    0

  5. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Sun Dec 31 13:37:17 CST 2017, time=2017-12-31, status=1, ipAttribution=)]
    2018-01-01 营养医师

    有鸡毛用.为发文章而编

    0

  6. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Sun Dec 31 13:37:17 CST 2017, time=2017-12-31, status=1, ipAttribution=)]
    2018-01-01 sunfeifeiyang

    学习

    0

  7. 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    2018-01-01 神功盖世

    学习

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  8. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Sun Dec 31 13:37:17 CST 2017, time=2017-12-31, status=1, ipAttribution=)]
    2017-12-31 阿杜12138

    0

  9. 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    2017-12-31 15121100f4m

    越来蓝莓抗癌是真的有科学依据的

    0

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    2017-12-31 131****1460

    学习了受益匪浅

    0

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JAND:蓝莓,有效降低高血压及动脉硬化

试想一下,如果在你的早餐麦片中加入一杯蓝莓,那么你就赶快干掉它吧!近日,一项发表于国际杂志Journal of the Academy of Nutrition and Dietetics上的一篇研究论文中,来自佛罗里达州立大学的研究人员通过研究表明,每天一杯蓝莓或可有效降低机体血压和动脉硬化,而这两种疾病都和心血管疾病直接相关。 研究者Sarah A. Johnson表示,有规律地食用蓝莓

ACS 251:阿尔茨海默症老人食用蓝莓可改善认知功能

俄亥俄州辛辛那提大学的Robert Krikorian博士等研究人员将研究结果在第251届美国化学学会(ACS)上指出。 他们指出,这一发现证实了既往的动物研究和初步的人体试验,说明蓝莓有助于改善老人的记忆和认知功能。蓝莓的颜色是由于花青素所致,其他水果和蔬菜都有类似的颜色,如红莓、红叶卷心菜和茄子等。既往研究指出花青素可预防心血管疾病、神经退行性疾病和某些癌症。 阿尔茨海默氏症协会指出,在201

盘点:预防改善高血压有良方 你知道多少?

本文中,小编整理了多篇研究来阐明如何有效预防和改善高血压症状,分享给各位! 本文中,小编整理了多篇研究来阐明如何有效预防和改善高血压症状,分享给各位! 【1】AJH:女性孕期机体叶酸水平较高或可降低后代患高血压的风险 DOI:10.1093/ajh/hpx003 发表在国际杂志American Journal of Hypertension上的一篇研究报告中,来自国外的研究人员通