Eur Heart J:冠脉支架置入后再狭窄可预测患者死亡率

2014-12-05 高晓方 译 医学论坛网

德国一项研究表明,冠脉支架置入后随访造影检出的再狭窄可预测患者4年死亡率。论文10月8日在线发表于《欧洲心脏杂志》(Eur Heart J)。 此项研究共纳入10004例因新发病变成功置入冠脉支架并在6~8个月后接受常规对照造影的患者,并以随访造影时节段区域内直径狭窄≥50%定义再狭窄。主要转归为4年死亡率。评估再再狭窄对4年死亡的影响。 结果显示,2643例(26.4%)患者存在

德国一项研究表明,冠脉支架置入后随访造影检出的再狭窄可预测患者4年死亡率。论文10月8日在线发表于《欧洲心脏杂志》(Eur Heart J)。

此项研究共纳入10004例因新发病变成功置入冠脉支架并在6~8个月后接受常规对照造影的患者,并以随访造影时节段区域内直径狭窄≥50%定义再狭窄。主要转归为4年死亡率。评估再再狭窄对4年死亡的影响。

结果显示,2643例(26.4%)患者存在再狭窄。随访期间共有702例患者死亡,其中伴和未伴再狭窄死亡患者分别为218和484例(未校正危险比[HR] 1.19;P=0.03)。利用Cox比例风险模型对其他变量进行校正之后,再狭窄为4年死亡的独立预测因素(HR 1.23),其他预测因素包括年龄、糖尿病、当前吸烟和左室射血分数。

原始出处:

Cassese S1, Byrne RA1, Schulz S1, Hoppman P2, Kreutzer J1, Feuchtenberger A1, Ibrahim T2, Ott I1, Fusaro M1, Schunkert H1, Laugwitz KL2, Kastrati A3.Prognostic role of restenosis in 10 004 patients undergoing routine control angiography after coronary stenting.Eur Heart J. 2014 Oct 8. pii: ehu383. [Epub ahead of print]



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    2014-12-07 智智灵药
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