Cardiovasc Ther:BMI如何影响心衰患者全因死亡率?

2017-04-14 顾歆纯;吴刚 环球医学

2017年4月,发表在《Cardiovasc Ther》的一项由中国科学家进行的前瞻性队列研究的剂量效应Meta分析考察了心衰(HF)患者中,体重指数(BMI)和全因死亡率之间的U型相关性背景和目的:BMI在HF患者预后中的作用仍然是长期的兴趣点所在。但是,BMI和HF患者死亡风险之间精确的剂量效应关系仍然未知。

2017年4月,发表在《Cardiovasc Ther》的一项由中国科学家进行的前瞻性队列研究的剂量效应Meta分析考察了心衰(HF)患者中,体重指数(BMI)和全因死亡率之间的U型相关性

背景和目的:BMI在HF患者预后中的作用仍然是长期的兴趣点所在。但是,BMI和HF患者死亡风险之间精确的剂量效应关系仍然未知。研究人员进行了一项剂量效应Meta分析,旨在定量评估BMI对HF患者全因死亡率的影响。

方法:14项前瞻性队列研究从46794名HF患者中鉴别出13508例死亡病例。

结果:BMI每增加5单位的总体HR为0.95(95% CI,0.92~0.97),证据具有较高异质性(I2=90.10%,异质性P<0.000001),并显示出BMI和全因死亡风险之间存在U型的非线性关系(P非线性=0.0025)。当进行分层分析时,超过60岁的HF患者的异质性降低。

结论:具有较高BMI(>28kg/m2)的心衰患者具有更佳的生存期,而体重过轻和严重肥胖(如,BMI>37kg/m2)的患者具有较高的死亡率。

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    2018-01-03 quxin068
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    2017-04-17 天涯183

    非常好的文章,学习了

    0

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    2017-04-15 往日如昨

    BMI在HF患者预后中的作用仍然是长期的兴趣点所在

    0

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    2017-04-15 lemon985

    分享

    0

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    2017-04-14 九天.

    mark

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1938666, encodeId=809919386669b, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Wed Jan 03 23:33:00 CST 2018, time=2018-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=188114, encodeId=7def188114cc, content=非常好的文章,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Mon Apr 17 07:47:29 CST 2017, time=2017-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1251466, encodeId=85591251466d1, content=<a href='/topic/show?id=874529332ba' target=_blank style='color:#2F92EE;'>#全因死亡率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29332, encryptionId=874529332ba, topicName=全因死亡率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=796422, createdName=lvliquan, createdTime=Sun Apr 16 03:33:00 CST 2017, time=2017-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1373335, encodeId=e3cb13e33356c, content=<a href='/topic/show?id=2fd051939ab' target=_blank style='color:#2F92EE;'>#心衰患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51939, encryptionId=2fd051939ab, topicName=心衰患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=467c360, createdName=yuanming7, createdTime=Sun Apr 16 03:33:00 CST 2017, time=2017-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=187663, encodeId=10f718e663ba, content=BMI在HF患者预后中的作用仍然是长期的兴趣点所在, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0a61971598, createdName=往日如昨, createdTime=Sat Apr 15 12:46:39 CST 2017, time=2017-04-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=187507, encodeId=888b18e50755, content=分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ca432042642, createdName=lemon985, createdTime=Sat Apr 15 00:12:49 CST 2017, time=2017-04-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=187395, encodeId=6fbc18e39591, content=mark, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/05/02/48d1fec880a796cc2ad284d7b18e6017.jpg, createdBy=43e51704272, createdName=九天., createdTime=Fri Apr 14 14:35:43 CST 2017, time=2017-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=187337, encodeId=7c2c18e33742, content=非常好的文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Fri Apr 14 12:39:07 CST 2017, time=2017-04-14, status=1, ipAttribution=)]
    2017-04-14 天涯183

    非常好的文章

    0

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