Front Neurosci:杏仁核连接中断与感音神经性听力损失患者焦虑加重有关

2021-01-27 AlexYang MedSci原创

听力损失与情绪障碍风险升高有关,表明情绪处理网络可能参与了听力损失后的神经可塑性。

听力损失与情绪障碍风险升高有关,表明情绪处理网络可能参与了听力损失后的神经可塑性

最近,有研究人员探索了听觉剥夺脑中杏仁核的功能连接如何重构,从而更好地理解听力损失相关情绪障碍的神经机制。研究共包括了38名慢性感音神经性听力损失(SNHL)患者和37名健康对照。研究结果表明,与健康对照组相比,SNHL患者的抑郁和焦虑水平更高。在SNHL患者的杏仁核与听觉皮层、纹状体、多模态处理区和额顶控制区之间的功能性连接(FCs)减少。杏仁核在结构上通过钩束(UF)与多个FC降低区域相连。此外,研究人员还发现低同步化和白质损害都与患者焦虑状态的加重有关。

SNHL组与对照组相比杏仁核FCs的差异

最后,研究人员指出,这些功能和结构上的发现描绘了SNHL中杏仁核的重构,为与听力损失相关的情感障碍的功能回路机制提供了一个新的视角

原始出处:

Tian-Yu Tang, Ying Luan, Yun Jiao et al. Disrupted Amygdala Connectivity Is Associated With Elevated Anxiety in Sensorineural Hearing Loss. Front Neurosci. Dec 2020

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    2021-01-29 ysjykql
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    2021-01-29 lsndxfj
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    2021-01-27 明天jing

    焦虑是当年年轻人的共同问题,需要认真对待。

    0

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