Heart:经皮冠状动脉介入治疗的急性心肌梗死患者年龄与再入院之间的相关性

2020-03-09 MedSci原创 MedSci原创

该研究的结果表明,校正协变量后,年轻患者意外的全因再入院的风险更高。再入院风险随年龄的变化趋势因特定原因而有所不同。针对年龄的干预措施可减少接受PCI治疗的AMI患者可预防的再入院风险。

近日,心脏病领域权威杂志Heart上发表了一篇研究文章,这项研究旨在调查接受经皮冠状动脉介入治疗(PCI)的急性心肌梗死(AMI)成年患者年龄与30天意外再入院风险之间的关系。

这项回顾性分析包含了来自美国全国再入院数据库的AMI患者,这些患者在2013-2014年期间接受了PCI治疗。研究人员使用多变量logistic回归模型来计算再次入院风险的校正比值比(AOR)。为了评估潜在的非线性关联,研究人员使用受限三次样条(RCS)进行了logistic回归分析。

492550名18岁以上的AMI患者在住院期间接受了PCI,其中48630名(9.87%)患者在30天内再次入院。尽管年轻患者(18-54岁)的粗略再入院率最低(7.27%),针对协变量进行调整后,与55-64岁患者相比,年轻患者的全因(AOR为1.06(1.01至1.11),p=0.0129)和特定原因,例如的AMI和胸痛(包括心脏性和非特异性),再入院风险更高。65-74岁的患者全因再入院的风险较低。年龄较大(≥75岁)的患者因心力衰竭(AOR为1.50(1.29至1.74))和感染(AOR为1.44(1.16至1.79))再入院的风险较高,但发生胸痛的风险较低。RCS分析显示年龄与再入院风险之间呈U型关系。

该研究的结果表明,校正协变量后,年轻患者意外的全因再入院的风险更高。再入院风险随年龄的变化趋势因特定原因而有所不同。针对年龄的干预措施可减少接受PCI治疗的AMI患者可预防的再入院风险。

原始出处:

Yingyi Qin.et al.Association between age and readmission after percutaneous coronary intervention for acute myocardial infarction.heart.2020.http://dx.doi.org/10.1136/heartjnl-2019-316103

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    2020-03-11 zhaojie88
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    2020-03-11 slcumt