Menopause:激素替代治疗会导致耳聋?!

2017-05-12 tulip1999 来宝网

数以千万计的美国人饱受听力损失的困扰。一项最新研究调查了绝经年龄、口服激素治疗与听力损失之间的联系,这是该领域首次进行的大规模研究。

数以千万计的美国人饱受听力损失的困扰。一项最新研究调查了绝经年龄、口服激素治疗与听力损失之间的联系,这是该领域首次进行的大规模研究。

世界卫生组织(WHO)将听力损失定义为听不到25分贝或低于语音的声音。这往往会导致理解对话和听到某些声音出现困难。

据报道,多达4,800万美国人,即超过20%以上的美国居民饱受听力损失的困扰。

女性出现听力损失的风险明显低于男性。在20岁到69岁这个年龄段,言语频率听力损失的男性患者是女性的两倍。

虽然还不清楚为什么女性比较不容易出现听力损失,但已经有一些研究表明,女性雌激素对内耳有保护作用。众所周知,雌激素会影响到人体各个部位的细胞,包括心脏、大脑和血管

此外,在出现听力受损的女性当中,绝经后女性更容易出现这种情况。在绝经期,孕激素和雌激素水平开始下降——更有理由进一步认为,这些性激素与听力受损有关。

这使得一些研究人员认为,激素替代疗法会降低听力损失的风险。然而,其他研究已经对这一推测提出挑战,指出激素治疗(HT)可能带来的严重副作用。

在这种情况下,这项最新研究开始着手研究激素治疗(HT)与听力损失之间的联系,这是一项大型的前瞻性研究。该研究成果发表在《更年期》杂志上。

这项研究对近81,000名在研究开始时年龄在27到44岁之间的健康女性的数据进行了分析。之后在1991年至2013年期间对其进行了长达22年的临床随访。在此期间,女性自我报告她们的听力损失情况及口服激素治疗(HT)的使用情况。

将近有23%的参与者(即18,558名女性)在随访期间出现一定程度的听力损失。

参与者所采取的激素治疗(HT)包括雌激素治疗或是雌激素加孕激素。

研究发现,绝经后女性使用口服激素治疗(HT)以及长期使用口服激素治疗(HT)听力损失风险增高有关。

这意味着激素治疗(HT)会增加听力损失的风险,且使用时间越长,风险越高。

原始出处:

Curhan, Sharon G, et al. Menopause and postmenopausal hormone therapy and risk of hearing loss. Menopause: Post Author Corrections: May 8, 2017.doi: 10.1097/GME.0000000000000878

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    2017-07-07 lofter

    学习了,感谢分享!

    0

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    2017-06-28 lofter

    学习了,感谢分享

    0

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    2017-05-17 QFXL123456

    搜索相关资料看看

    0

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    2017-05-12 打渔晒网

    真的影响听力吗

    0

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