低镁血症:糖尿病终末期肾病新预测因素

2012-04-20 佚名 中国医学论坛报手机报

  日本一项研究报告,对于2型糖尿病肾病患者,低镁血症是其终末期肾病(ESRD)的新预测因素。研究于4月12日在线发表于《糖尿病护理》(Diabetes Care)杂志。   这是一项回顾性队列研究,纳入455例慢性肾病(CKD)患者,其中144例为2型糖尿病肾病患者,另外311例CKD患者不伴有糖尿病。根据血镁水平,受试者被分为低镁(≤1.8 mg/dl)组和高镁(>

  日本一项研究报告,对于2型糖尿病肾病患者,低镁血症是其终末期肾病(ESRD)的新预测因素。研究于4月12日在线发表于《糖尿病护理》(Diabetes Care)杂志。

  这是一项回顾性队列研究,纳入455例慢性肾病(CKD)患者,其中144例为2型糖尿病肾病患者,另外311例CKD患者不伴有糖尿病。根据血镁水平,受试者被分为低镁(≤1.8 mg/dl)组和高镁(>1.8 mg/dl)组。结果显示,在对2型糖尿病肾病患者平均23个月随访期间,有102例进展至ESRD,且多变量Cox比例风险模型显示,在校正人群特征和实验室数据后,低镁组患者进展至ESRD的风险比高镁组高2.12倍(P = 0.004)。相反,在对311例非糖尿病CKD患者平均44个月的随访期间,135例进展至ESRD,且低镁组、高镁组的ESRD风险无显著差异(P=0.57)。



    

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