Gastroenterology:结肠非整倍体检测与结肠癌风险评估

2017-08-28 zhangfan MedSci原创

非整倍体检测可以考察结肠低度异型增生的疾病恶化风险

对于结肠炎性肠病(IBD)低度异型增生 (fLGD)患者的治疗及其临床意义,目前仍存在较大争议。

近日研究人员对37名IBD患者的结肠镜检查标本数据进行回顾性分析以考察结肠炎性肠病非整倍体检查与后续高度异型增生 (HGD) 或结肠癌(CRC)之间的关系。

研究人员对患者的治疗资料进行收集,平均随访37个月。患者结肠组织流式细胞分析结果表明,37份样本中,15例存在低度异型增生(40.5%),对这15例低度异型增生标本进行非整倍体检查发现其中14例存在高度异型增生(93.3%),所有样本中仅2例异常增生阴性(4.4%)。对于低度异型增生患者,37个月内累积的高度异常增生或结肠癌风险为5.3% (95% CI, 1.542-24.121)。

研究认为,非整倍体检测可以考察结肠低度异型增生的疾病恶化风险。

原始出处:


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    2018-01-02 sjq027
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    2018-01-13 许安
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    2017-08-30 marongnuan
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    2017-08-28 三生有幸9135

    学习一下谢谢分享

    0

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    2017-08-28 doctorJiangchao

    谢谢分享.

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