J Periodontol:使用聚丙交酯 - 共 - 乙交酯涂层的β-磷酸三钙骨移植修复颊骨缺损的拔牙窝

2019-03-04 不详 网络

拔牙后牙槽嵴的高度和宽度明显减小。本研究旨在比较评估涂有聚丙交酯-共-乙交酯(β-TCP /PLGA)和常规颗粒β-TCP的β-磷酸三钙在拔牙窝颊骨缺损中的位点保存的效果。在六只小猎犬中,去除其颊骨板后提取上颌第一前磨牙。在抽取插口的位置产生标准化的骨缺损(4 [近中远端宽度]×4 [buccopalatal宽度]×5 [深度] mm)并填充β-TCP / PLGA(测试部位)或颗粒β-TCP(对

拔牙后牙槽嵴的高度和宽度明显减小。本研究旨在比较评估涂有聚丙交酯-共-乙交酯(β-TCP /PLGA)和常规颗粒β-TCP的β-磷酸三钙在拔牙窝颊骨缺损中的位点保存的效果。

在六只小猎犬中,去除其颊骨板后提取上颌第一前磨牙。在抽取插口的位置产生标准化的骨缺损(4 [近中远端宽度]×4 [buccopalatal宽度]×5 [深度] mm)并填充β-TCP / PLGA(测试部位)或颗粒β-TCP(对照部位) )。手术后12周进行微计算机断层扫描,组织学组织学评估。

结果,试验部位的骨量明显大于对照部位(25.7±2.14对16.0±3.3 mm3),但骨材料密度无统计学差异(分别为746.3±23.9 vs. 714.5±37.0 g / cm3)。相对于对照部位,测试部位表现出明显更大的牙槽嵴冠状面(2.0±0.4对1.1±0.3 mm)和中间(2.9±0.2对2.1±0.3 mm)水平宽度和编织骨比例(50.3± 8.1%对38.0±5.2%)和骨髓(17.7±6.6%对比9.7±4.1%),但结缔组织比例明显较低(10.7±4.5%对18.3±5.7%)。

总之,在本研究的限制范围内,可模塑的β-TCP/PLGA移植物似乎比常规的颗粒β-TCP移植物具有更大的潜力,用于保存颊骨缺陷的拔牙窝的牙槽嵴。

原始出处:

Okada M, Matsuura T, et al., Ridge preservation of extraction sockets with buccal bone deficiency using poly lactide-co-glycolide coated beta-tricalcium phosphate bone grafts: An experimental study in dogs. J Periodontol. 2019 Feb 28. doi: 10.1002/JPER.18-0574.

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    2020-02-02 feather89
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    2019-05-22 howi
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    2019-03-06 lfcmxl
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    2019-03-06 xre2013