乙酸对烧伤创面易感病原菌的抑制作用

2016-10-23 中华烧伤杂志2016年第32卷第2期 中华烧伤杂志

由烧伤创面局部感染引起的脓毒症是烧伤患者死亡的主要诱因之一,因此防治创面感染是救治的关键所在。乙酸是一种常见的具有抑菌效应的酸类。病原菌主要通过其自身产生的生物膜增加游走性和侵入性,从而引起全身性感染。 本研究旨在探讨乙酸对烧伤患者易感病原菌的游走性和生物膜形成的抑制作用,并明确其最小有效浓度。作者从烧伤科中分离出29株易引起创面感染的病原菌,进行体外培养。 在生长培养基中加入

由烧伤创面局部感染引起的脓毒症是烧伤患者死亡的主要诱因之一,因此防治创面感染是救治的关键所在。乙酸是一种常见的具有抑菌效应的酸类。病原菌主要通过其自身产生的生物膜增加游走性和侵入性,从而引起全身性感染。

 

本研究旨在探讨乙酸对烧伤患者易感病原菌的游走性和生物膜形成的抑制作用,并明确其最小有效浓度。作者从烧伤科中分离出29株易引起创面感染的病原菌,进行体外培养。

 

在生长培养基中加入低体积分数乙酸(体积分数为0.026%~1.600%),观察病原菌的生长情况。结果显示,虽然不同病原菌对不同体积分数乙酸的反应不同,但当乙酸体积分数达到0.310%时,29株病原菌游走性和生物膜的形成均受到抑制;当乙酸体积分数达到1.250%时,绝大部分病原菌已经产生的生物膜也可被清除。

 

研究结果表明,低体积分数的乙酸可发挥有效的抑菌作用。本研究对临床上防治烧伤患者创面感染、预防脓毒症发生,具有重要应用价值。

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    2017-09-21 qindq
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    2016-11-17 KO229256262

    中华牌出来的,相信是好东西

    0

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    2016-11-13 虈亣靌

    学习了,分享

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1631985, encodeId=a26716319851c, content=<a href='/topic/show?id=b88a321e6b2' target=_blank style='color:#2F92EE;'>#创面#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32176, encryptionId=b88a321e6b2, topicName=创面)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6fda21837820, createdName=qindq, createdTime=Thu Sep 21 04:28:00 CST 2017, time=2017-09-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1739355, encodeId=b7b41e39355e9, content=<a href='/topic/show?id=3344e0820a0' target=_blank style='color:#2F92EE;'>#病原菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70820, encryptionId=3344e0820a0, topicName=病原菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=350334527944, createdName=zjshifan_98647317, createdTime=Thu Feb 02 13:28:00 CST 2017, time=2017-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1635427, encodeId=f5e0163542eae, content=<a href='/topic/show?id=b099549160a' target=_blank style='color:#2F92EE;'>#抑制作用#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54916, encryptionId=b099549160a, topicName=抑制作用)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6cd322475383, createdName=124987a0m73(暂无昵称), createdTime=Sat Mar 18 07:28:00 CST 2017, time=2017-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=156482, encodeId=65011564829e, content=中华牌出来的,相信是好东西, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/12/17/3872cad7a53dc9dcbd08202fb6313cf4.jpg, createdBy=2cb71609450, createdName=KO229256262, createdTime=Thu Nov 17 23:32:21 CST 2016, time=2016-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=155453, encodeId=30f41554535b, content=学习了,分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sun Nov 13 12:19:42 CST 2016, time=2016-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1536093, encodeId=df8315360939b, content=<a href='/topic/show?id=fe056e145d5' target=_blank style='color:#2F92EE;'>#烧伤创面#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67145, encryptionId=fe056e145d5, topicName=烧伤创面)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=hb2008ye, createdTime=Tue Oct 25 07:28:00 CST 2016, time=2016-10-25, status=1, ipAttribution=)]