ANN NEUROL:吃青椒可预防帕金森氏症
2013-05-13 koo 生物360
吃青椒可以预防帕金森氏症？ 许多小朋友可能都跟卡通人物蜡笔小新一样不敢吃青椒，把它当成最可怕的食物， 不过国外有研究发现，吃青椒可以预防帕金森氏症，华盛顿大学研究指出，每个礼拜吃两次茄科蔬菜的人，像是青椒甜椒辣椒番茄茄子，可以预防帕金森氏症罹患的机率可降至少三成。 研究认为，是因为基底核会受到烟碱的刺激，可以增加大脑多巴胺的含量，有助降低帕金森式风险。 与帕金森相关的拓展阅读：
吃青椒可以预防帕金森氏症？
许多小朋友可能都跟卡通人物蜡笔小新一样不敢吃青椒，把它当成最可怕的食物， 不过国外有研究发现，吃青椒可以预防帕金森氏症，华盛顿大学研究指出，每个礼拜吃两次茄科蔬菜的人，像是青椒甜椒辣椒番茄茄子，可以预防帕金森氏症罹患的机率可降至少三成。
研究认为，是因为基底核会受到烟碱的刺激，可以增加大脑多巴胺的含量，有助降低帕金森式风险。
与帕金森相关的拓展阅读：
- Nature：新研究挑战现有的帕金森病认识
- Nat Commun：新型化合物可有效降低帕金森疾病的发病进程
- PLOS ONE：研究揭示帕金森病相关突触核蛋白的迁移特性
- AAN 2013：帕金森病精神症状治疗新药Pimavanserin效果良好
- NEJM：脑刺激配合药物治疗早期帕金森更优
- NEJM：下丘脑刺激有助于改善早期帕金森症状 更多信息请点击：有关帕金森更多资讯
Objective
To test whether risk of Parkinson disease (PD) is associated with consumption of nicotine-containing edibles from the same botanical family as tobacco, Solanaceae, including peppers, tomatoes, and potatoes.
Methods
In a population-based study with 490 newly diagnosed idiopathic PD cases diagnosed during 1992–2008 at the University of Washington Neurology Clinic or Group Health Cooperative in western Washington State and 644 unrelated, neurologically normal controls, we examined whether PD was associated with self-reported typical frequency of consumption of peppers, tomatoes, tomato juice, and potatoes during adulthood, while adjusting for consumption of other vegetables, age, sex, race/ethnicity, tobacco use, and caffeine.
Results
PD was inversely associated with consumption of all edible Solanaceae combined (relative risk [RR] = 0.81, 95% confidence interval [CI] = 0.65–1.01 per time per day), but not consumption of all other vegetables combined (RR = 1.00, 95% CI = 0.92–1.10). The trend strengthened when we weighted edible Solanaceae by nicotine concentration (ptrend = 0.004). An inverse association was also evident for peppers specifically (ptrend = 0.005). The potentially protective effect of edible Solanaceae largely occurred in men and women who had never used tobacco or who had smoked cigarettes <10 years.
Interpretation
Dietary nicotine or other constituents of tobacco and peppers may reduce PD risk. However, confirmation and extension of these findings are needed to strengthen causal inferences that could suggest possible dietary or pharmaceutical interventions for PD prevention. Ann Neurol 2013
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本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料，版权均属于梅斯医学所有。非经授权，任何媒体、网站或个人不得转载，授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章，或“梅斯号”自媒体发布的文章，仅系出于传递更多信息之目的，本站仅负责审核内容合规，其内容不代表本站立场，本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系，我们将立即进行删除处理。
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#青椒#
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#预防帕金森#
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#Neurol#
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