Radiology:评价冠脉部分血流储备,哪种方法更好呢?

2018-01-28 shaosai MedSci原创

本研究旨在比较不同CT部分血流储备(FFR)算法对病变血管评价的诊断准确率,并将结果发表在Radiology上。

本研究旨在比较不同CT部分血流储备(FFR)算法对病变血管评价的诊断准确率,并将结果发表在Radiology上。

本研究共纳入了61例CTA显示有中度狭窄(25%-69%)并于90天内行FFR评价的患者(平均年龄69±10,年龄范围29-89岁)。对每一处病变的CT FFR诊断准确性利用3种方法进行测试进而评估CT FFR计算的血流分布。Murray法和 Huo-Kassab规则对冠脉解剖进行评估,第三种用来评估对比剂浓度梯度。利用ROC AUC进行比较CT FFR算法和CTA管腔直径狭窄百分比(DS)。

结果为,共有25处病变(41%)FFR≤0.8。利用对比剂梯度的CT FFR的AUC要明显高于Huo-Kassab (AUC = 0.882, P = .043) Murray法模型 (AUC = 0.871, P = .033)。3总算法的AUC均高于CTA DS≥50%(AUC = 0.596, P < .001)。对比剂梯度的CT FFR与FFR相关性最高(Spearman ρ = 0.80),其次是Huo-Kassab规则(ρ = 0.68)和Murray法则 (ρ = 0.67)模型。所有CT FFR算法均有笑得偏倚,范围为-0.015 (Murray) to -0.049 (Huo-Kassab)。一致性差异最小的是对比剂梯度(-0.182, 0.147),其次是Huo-Kassab法则(-0.246, 0.149)和Murray法则。

本研究表明,临床医生可以进行4步法测算CT FFR来准确地检查中度狭窄病变的血流动力学异常。利用冠脉对比剂浓度差异来评价血流分布有助于提高CT FFR准确性。

原始出处:


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    2018-02-09 Drhzm308

    谢谢.学习了

    0

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    2018-01-30 huagfeg
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    2018-01-30 jyzxjiangqin

    评价冠脉部分血流储备.

    0

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    2018-01-29 120e71dcm28暂无昵称

    很有用

    0

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    2018-01-29 杨利洪

    学习了提高了

    0

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    2018-01-29 飛歌

    学习了很有用

    0

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    2018-01-28 戒馋,懒,贪

    谢谢分享学习了

    0

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    2018-01-28 李东泽

    是很好的学习材料.不错.以后会多学习.

    0

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