宫颈间质侵袭可预测子宫内膜癌患者的存活率

2011-06-07 Ferriss JS, Brix W, Tambouret R, DeSimone CP, Stoler M, Modesitt SC MedSci原创

    目的:估计可预测(子宫内膜癌患者)存活时间的宫颈间质侵袭程度。     方法:我们回顾了3个学术机构的2期子宫内膜样子宫内膜腺癌病例。一名妇科病理医师重新评价了已归档的切片,并测量了宫颈间质侵袭深度。提取临床数据并进行统计分析。     结果:在116例病例中,

    目的:估计可预测(子宫内膜癌患者)存活时间的宫颈间质侵袭程度。     方法:我们回顾了3个学术机构的2期子宫内膜样子宫内膜腺癌病例。一名妇科病理医师重新评价了已归档的切片,并测量了宫颈间质侵袭深度。提取临床数据并进行统计分析。     结果:在116例病例中,31例(27%)有腺体受累,85例(73%)有宫颈间质侵袭。宫颈间质侵袭被分类为宫颈内2/3 (n=59 [69%])和外1/3 (n=26 [31%])侵袭。与宫颈内2/3间质侵袭的患者相比,宫颈外1/3间质侵袭的患者在以下方面的比例更大:年龄至少为65岁(69%比 46%,P=0.038),至少侵袭子宫肌层50%(77%比44%,P=0.004),淋巴血管间隙侵袭(46%比20%,P=0.016),以及死亡(50%比19%,P=0.004)。无侵袭的患者与宫颈内2/3间质侵袭的总体存活时间并无差异(106个月比146个月,P=0.89)。宫颈外1 /3间质侵袭的患者的存活时间为91个月(P

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    2011-06-09 一闲