儿童湿疹:美国治疗六步曲,步步紧扣!

2016-12-17 石应珊医师 美国芝加哥大学Comer儿童医院; 社区儿童家庭医疗总策划 医学界儿科频道

在美国治疗湿疹有六步曲,从第一步开始步步紧扣。大多数轻症湿疹第一步避免过敏源和诱因加上第二步保湿止痒就足够应对,中重度湿疹需要用药时应遵循以下原则: •能用一种就不要用两种;•尽量用经典老药,因为它们的疗效和副作用观察时间长;•用每种药必须查明其忌用禁用和年龄限制;•应用每种药一定要知道它治疗什么,主要活性成分和副作用;•联合用多种药时必须知道为什么要同时用药,以及相互作用和联合用药的副

在美国治疗湿疹有六步曲,从第一步开始步步紧扣。大多数轻症湿疹第一步避免过敏源和诱因加上第二步保湿止痒就足够应对,中重度湿疹需要用药时应遵循以下原则: 


•能用一种就不要用两种;
•尽量用经典老药,因为它们的疗效和副作用观察时间长;
•用每种药必须查明其忌用禁用和年龄限制;
•应用每种药一定要知道它治疗什么,主要活性成分和副作用;
•联合用多种药时必须知道为什么要同时用药,以及相互作用和联合用药的副作用;最好是一种一种的用;一种失败之后再用另外一种。


一个优秀的儿科医生不但能诊断、鉴别诊断和用最简单的方法和最少的药物缓解和预防湿疹。还应该精通孩子父母和家庭的湿疹预防和疹疗的教育。下面是为医生治疗湿疹和为湿疹孩子的家庭提供的湿疹家庭应对方法。


什么是湿疹?


干性皮肤炎症反应:干痒红疹,复发慢性 ,排除其他原因。湿疹可以持续几个月,几年,甚至一辈子。


湿疹的原因


原因并不确定,可能与遗传,环境,食物过敏有关;但皮肤屏障功能障碍导致皮肤水分丢失和外界刺激物、过敏原和病菌的侵入。 


湿疹的治疗—六步曲


第1步:避免过敏源和诱因


这是最重要的一步,但很多时候不一定能发现过敏源和诱因。


避免易过敏食物:鸡蛋,牛奶,豆,鱼,花生 。母乳喂养的妈妈和加辅食的孩子应该轮流停吃易过敏食物,每种5天,检查食物与湿疹严重度的关系。如果发现任何食物加重湿疹应避免,并登记好为今后做过敏试验做准备。


避免接触尘螨,动物毛, 潮湿真菌,化学物品接触物,家居凉爽通风干燥清洁,衣服全棉宽松,用经典皮肤和洗澡用品。


喂养: 
母乳喂养—6个月加辅食—1-2岁加易过敏食物,配方奶粉喂养可考虑低敏配方奶粉,辅食添加应遵循少量开始、逐一添加5天一种、缓慢递增。


美国儿科学会最近更新指南,中度和重度湿疹的孩子应该做过敏原试验。


第2步:保湿止痒


外用润肤剂:凡士林油膏(Vaseline, 100% Pure Petroleum Jelly)、硼酸氧化锌冰片软膏、复方炉甘石洗剂。局部湿疹润肤油膏上加盖湿纱布效果更好。


湿疹的原因是皮肤屏障功能障碍导致皮肤水分丢失,外用润肤剂一定要用够。以油膏效果最好,每天6-8次或者更多,保持24小时皮肤湿润。孩子24小时呈小油人了,避免了过敏源和诱因, 很多湿疹不需要任何药物就能控制好。


第3步:消炎止痒 (美国经典常用药)


在医生指导下用药;


第一代抗组胺药内服
苯海拉明(新生儿及早产儿忌用)


第二代抗组胺药内服
仙特明/西替立嗪 (在美国6月以下婴儿禁用);
氯雷他定(在美国6月以下婴儿禁用, 2岁以下儿童不推荐使用 ) 


外用激素
如果避免过敏源和诱因,外用润肤剂保湿和抗组胺药结合不能控制湿疹,外用激素是下一步最好的选择。与其他外用消炎药如外用免疫抑制剂相比更为安全,是治疗湿疹的首选消炎外用药。因湿疹的部位和严重程度选药定量。


只在疹红搔痒明显时(急性/亚急性期)使用:每天2次,最短不少于1-2周, 可以连续用3-4周;对特别严重的湿疹,可以长期间断用药;根据湿疹的严重度弱效中效交替使用。


脸部颈部湿疹(尽量用弱效激素):
以0.5% 氢化可的松霜剂或油膏开始,油膏更好; 到1%和2.5%氢化可的松油膏
身体其他部位(可用弱或中效激素):
以1% 氢化可的松油膏开始, 到2.5%氢化可的松油膏,氟新诺龙0.025%油膏, 或去炎松/氟羟泼尼松龙0.1%油膏。


外用激素弱、中、强效制剂 
弱效激素:氢化可的松1%油膏,2.5%油膏;
中效激素:氟新诺龙0.025%油膏;去炎松/氟羟泼尼松龙0.1%油膏; 
高效激素:氟新诺龙0.1%油膏;去炎松/氟羟泼尼松龙0.5%油膏。


第4步:湿疹继发感染


原有皮疹更红,湿,黄色痂;常见金色葡萄球菌;在美国多用外用2%莫匹罗星软膏(Mupironcin ointment) 或口服抗菌素,第一代头孢霉素如赐福力欣(Cephalexin, Keflex);如果考虑青霉素耐药金色葡萄球菌,则用口服克林霉素(Clindamycin) 。


湿疹较少合并真菌感染,如有合并可用外用抗真菌药。


第5步:皮肤科医生就诊


如诊断不明,治疗无效,年幼重型;脸部颈部湿疹需要用中效激素,身体其他部位湿疹需要用高效外用激素如氟新诺龙0.1%油膏或去炎松/氟羟泼尼松龙0.5%油膏等。


第6步:湿疹的预防


避免过敏源和诱因和强力皮肤保湿止痒。

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    2022-03-24 ms9000000080461052

    `学习了

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    2017-05-23 美丽明天在等我

    湿疹是常见,易反复,不易根治的毛病

    0

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    2017-05-07 王秀

    学习了,当一个好医生不容易

    0

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    2017-05-02 summerqqz

    学习了

    0

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    2016-12-18 半夏微凉

    学习了,谢谢!

    0