J Clin Pharm Ther:芦荟也能控制血糖?

2016-03-30 Seven L MedSci原创

近期一项荟萃分析显示,芦荟可改善前驱糖尿病患者的空腹血糖(FPG),改善2型糖尿病患者的糖化血红蛋白(HbA1c)!该荟萃分析共纳入了8项随机临床试验,涉及470名患者,其中有6篇文献是比较芦荟和安慰剂,还有2篇文献是比较芦荟和未治疗患者间,对前驱糖尿病(3篇)或2型糖尿病(5篇)血糖控制的影响。文献中的芦荟制剂包括粉碎的芦荟叶、新鲜提取的芦荟汁、芦荟凝胶粉、芦荟提取物等,治疗时间为2-3个月,大

近期一项荟萃分析显示,芦荟可改善前驱糖尿病患者的空腹血糖(FPG),改善2型糖尿病患者的糖化血红蛋白(HbA1c)!

该荟萃分析共纳入了8项随机临床试验,涉及470名患者,其中有6篇文献是比较芦荟和安慰剂,还有2篇文献是比较芦荟和未治疗患者间,对前驱糖尿病(3篇)或2型糖尿病(5篇)血糖控制的影响。文献中的芦荟制剂包括粉碎的芦荟叶、新鲜提取的芦荟汁、芦荟凝胶粉、芦荟提取物等,治疗时间为2-3个月,大多数研究在伊朗进行。

研究者根据治疗组和对照组患者的FPG和HbA1c平均差异评估芦荟的效果。

荟萃分析数据显示,芦荟可降低前驱糖尿病患者的FPG(平均差  –0.22 mmol/L; 95% CI, –0.32 to –0.12);芦荟可改善2型糖尿病患者的FPG(平均差  –1.17 mmol/L; 95% CI, –2.35 to 0)。

不过芦荟补充剂只能改善2型糖尿病患者的HbA1c(平均差 –11 mmol/mol; 95% CI, –19 to –2),对前驱糖尿病患者的HbA1c影响不大。

研究人员写道:“研究结果表明,芦荟可能有益于前驱糖尿病和2型糖尿病患者的血糖控制。不过因为荟萃分析纳入的研究质量低,研究结果间异质性大,未来还需要高质量的随机对照试验,来探究芦荟对糖尿病这一块的影响和临床意义。”

原始出处:

Suksomboon N, et al. Effect of Aloe vera on glycaemic control in prediabetes and type 2 diabetes: a systematic review and meta-analysis.J Clin Pharm Ther. 2016;doi:10.1111/jcpt.12382.

Aloe vera may improve glycemic control in prediabetes, type 2 diabetes.Healio.March 29, 2016

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  2. [GetPortalCommentsPageByObjectIdResponse(id=1934538, encodeId=997819345384a, content=<a href='/topic/show?id=b65a56e400e' target=_blank style='color:#2F92EE;'>#控制血糖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56740, encryptionId=b65a56e400e, topicName=控制血糖)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=71f1477, createdName=s_pl2008, createdTime=Thu Mar 09 15:12:00 CST 2017, time=2017-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1787187, encodeId=18011e87187db, content=<a href='/topic/show?id=fa03141591e' target=_blank style='color:#2F92EE;'>#Pharm#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14159, encryptionId=fa03141591e, topicName=Pharm)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8942242, createdName=jj000001, createdTime=Thu Aug 25 13:12:00 CST 2016, time=2016-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=85086, encodeId=180a850864e, content=我家阳台有好多芦荟, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/PiajxSqBRaEIsrUxHnicsiaqwzJibCks60HOicbEAgbNzUiciboMJDzsWg16OHTeNHhyYvTg6TDXTlOx7icnhttCYYe2ujYt0yND7dYusOsibl9XnQCE/0, createdBy=7ad21722200, createdName=jaysppr, createdTime=Mon May 09 18:21:00 CST 2016, time=2016-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=79284, encodeId=62d3e9284b0, content=只是改善, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cc71713672, createdName=hewenda, createdTime=Sun Apr 17 23:51:00 CST 2016, time=2016-04-17, status=1, ipAttribution=)]
    2016-08-25 jj000001
  3. [GetPortalCommentsPageByObjectIdResponse(id=1934538, encodeId=997819345384a, content=<a href='/topic/show?id=b65a56e400e' target=_blank style='color:#2F92EE;'>#控制血糖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56740, encryptionId=b65a56e400e, topicName=控制血糖)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=71f1477, createdName=s_pl2008, createdTime=Thu Mar 09 15:12:00 CST 2017, time=2017-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1787187, encodeId=18011e87187db, content=<a href='/topic/show?id=fa03141591e' target=_blank style='color:#2F92EE;'>#Pharm#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14159, encryptionId=fa03141591e, topicName=Pharm)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8942242, createdName=jj000001, createdTime=Thu Aug 25 13:12:00 CST 2016, time=2016-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=85086, encodeId=180a850864e, content=我家阳台有好多芦荟, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/PiajxSqBRaEIsrUxHnicsiaqwzJibCks60HOicbEAgbNzUiciboMJDzsWg16OHTeNHhyYvTg6TDXTlOx7icnhttCYYe2ujYt0yND7dYusOsibl9XnQCE/0, createdBy=7ad21722200, createdName=jaysppr, createdTime=Mon May 09 18:21:00 CST 2016, time=2016-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=79284, encodeId=62d3e9284b0, content=只是改善, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cc71713672, createdName=hewenda, createdTime=Sun Apr 17 23:51:00 CST 2016, time=2016-04-17, status=1, ipAttribution=)]
    2016-05-09 jaysppr

    我家阳台有好多芦荟

    0

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    2016-04-17 hewenda

    只是改善

    0