王本:循环肿瘤细胞(CTCs)芯片:癌症早期诊断、干预以及预后监测体系的建立与应用

2015-09-24 佚名 生物谷

9月17日,由生物谷主办的“2015生物标志物研讨会”在上海好望角大饭店隆重开幕。浙江大学转化医学研究院王本副教授参加了此次大会,并发表了题为“环肿瘤细胞(CTCs)芯片:癌症早期诊断、干预以及预后监测体系的建立与应用”的精彩报告。 王本教授在报告中指出: 1.循环肿瘤细胞的研究对于肿瘤复发和转移具有重要意义,它的分选富集将为肿瘤转移的生化和分子生物学的研究提供方法学和技术平台,同时为临床上的

9月17日,由生物谷主办的“2015生物标志物研讨会”在上海好望角大饭店隆重开幕。浙江大学转化医学研究院王本副教授参加了此次大会,并发表了题为“环肿瘤细胞(CTCs)芯片:癌症早期诊断、干预以及预后监测体系的建立与应用”的精彩报告。

王本教授在报告中指出:

1.循环肿瘤细胞的研究对于肿瘤复发和转移具有重要意义,它的分选富集将为肿瘤转移的生化和分子生物学的研究提供方法学和技术平台,同时为临床上的疾病诊断和个性化治疗提供线索。

2.借助生物界面工程方法,从细胞界面、材料多级结构与界面,以及生物芯片结构三个角度综合发展CTCs分选平台——包括分选设备和配套细胞芯片的一体化研发。重点聚焦于生物芯片的结构和界面,即几何结构和材料化学两方面优化细胞捕获的纯度、效率以及借助于智能材料的环境响应性实现目标细胞的选择性释放性能,然后,结合生物微机电系统和微流控芯片技术,发展了能够满足临床检测需求的CTCs检测系统和芯片。

3. CTCs芯片为建立癌症早期诊断、干预以及预后检测体系提供了理想的技术平台,并未发展广谱通用的细胞/微生物生物流体分选系统等共性关键技术奠定了科学基础。

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    2016-02-06 仁心济世
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    2015-11-21 kalseyzl
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    2016-02-21 marongnuan
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    2015-10-03 Charles Chow

    最近也在关注这个

    0

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    2015-09-26 lixiaol
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    1896年,澳大利亚学者Ashworth在一例转移性肿瘤患者血液中首次观察到从实体肿瘤中脱离并进入血液循环的肿瘤细胞,并率先提出了循环肿瘤细胞(CTC)的概念。近年来世界各国研究人员围绕CTC在乳腺癌、结直肠癌等肿瘤中的应用价值开展了多项探索研究。美国乔治敦大学医院教授Minetta Liu在日前于北京举行的“第十五届中国临床肿瘤学大会”上介绍,多数肿瘤几乎都