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Cell子刊：首次从动物体内分离出多分体病毒GCXV

2016-08-30 佚名 生物谷

病毒GCXV
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在一项新的研究中，来自美国陆军传染病医学研究所等机构的研究人员发现一种感染蚊子的新型多分体病毒（multicomponent virus）：这是首次从一种动物体内分离出的这样的一种病毒。这种新型病毒被研究人员命名为Guaico Culex病毒（Guaico Culex virus, GCXV），它的基因组由5个节段组成，每个节段被单独包装在不同的病毒粒子（virion）中。为了感染蚊子，这种病毒基


在一项新的研究中，来自美国陆军传染病医学研究所等机构的研究人员发现一种感染蚊子的新型多分体病毒（multicomponent virus）：这是首次从一种动物体内分离出的这样的一种病毒。这种新型病毒被研究人员命名为Guaico Culex病毒（Guaico Culex virus, GCXV），它的基因组由5个节段组成，每个节段被单独包装在不同的病毒粒子（virion）中。为了感染蚊子，这种病毒基因组的至少4个节段必需侵入宿主体内。相关研究结果于2016年8月25日在线发表在Cell Host & Microbe期刊上，论文标题为“A Multicomponent Animal Virus Isolated from Mosquitoes”。

澳大利亚悉尼大学病毒学家Edward Holmes（未参与这项研究）说，“这是最为奇特的。如果你将它与人体进行比较的话，它就好比一个人将他/她的腿、躯干和手臂都放在不同的地方。”

他补充道，“随后，所有的节段以某种方式集合在一起，像单分体病毒一样发挥作用。我认为自然界中还没有其他东西以这种方式行动。”

具有多节段基因组的病毒（即多分体病毒）经常感染植物和真菌，但是它们在动物体内是极其罕见的。

这项发现和描述了GCXV的研究是更好理解蚊媒病毒的更广泛努力的一部分。研究人员也在来自乌干达的红疣猴体内发现了这种新型病毒的变异体。不过GCXV似乎并不感染人类。

原始出处

Jason T. Ladner, Michael R. Wiley, Brett Beitzel, Albert J. Auguste, Alan P. Dupuis II, Michael E. Lindquist, Samuel D. Sibley, Krishna P. Kota.et.al.A Multicomponent Animal Virus Isolated from Mosquitoes.Cell Host & Microbe.2016

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    2017-05-23 Luyuxie_9

    #GCXV#

    0

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    2017-07-04 zhaozhouchifen

    #Cell#

    0

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createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Aug 31 10:48:00 CST 2016, time=2016-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108208, encodeId=1a75108208a4, content=学习了，赞一个！！！, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Aug 31 10:48:00 CST 2016, time=2016-08-31, status=1, ipAttribution=)]
    2017-03-07 维他命

    #CEL#

    0

  4. 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createdName=zhaozhouchifen, createdTime=Tue Jul 04 00:18:00 CST 2017, time=2017-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1959786, encodeId=5bef1959e8677, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Tue Mar 07 07:18:00 CST 2017, time=2017-03-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108231, encodeId=1dac108231ad, content=学习了，赞一个！！！, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Aug 31 10:55:00 CST 2016, time=2016-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108223, encodeId=c8a51082230b, content=学习了，赞一个！！！, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Aug 31 10:50:00 CST 2016, time=2016-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108214, encodeId=a0b910821459, content=学习了，赞一个！！！, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Aug 31 10:49:00 CST 2016, time=2016-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108217, encodeId=0fdf10821e41, content=学习了，赞一个！！！, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Aug 31 10:49:00 CST 2016, time=2016-08-31, status=1, ipAttribution=), 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createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Aug 31 10:48:00 CST 2016, time=2016-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108208, encodeId=1a75108208a4, content=学习了，赞一个！！！, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Aug 31 10:48:00 CST 2016, time=2016-08-31, status=1, ipAttribution=)]
    2016-08-31 1dd8a7c5m95(暂无匿称)

    学习了，赞一个！！！

    0

  5. 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createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Aug 31 10:48:00 CST 2016, time=2016-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108208, encodeId=1a75108208a4, content=学习了，赞一个！！！, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Aug 31 10:48:00 CST 2016, time=2016-08-31, status=1, ipAttribution=)]
    2016-08-31 1dd8a7c5m95(暂无匿称)

    学习了，赞一个！！！

    0

  6. 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likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Aug 31 10:49:00 CST 2016, time=2016-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108217, encodeId=0fdf10821e41, content=学习了，赞一个！！！, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Aug 31 10:49:00 CST 2016, time=2016-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108221, encodeId=284c108221c3, content=学习了，赞一个！！！, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Aug 31 10:49:00 CST 2016, time=2016-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108206, encodeId=5f5c108206d7, content=学习了，赞一个！！！, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Aug 31 10:48:00 CST 2016, time=2016-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108208, encodeId=1a75108208a4, content=学习了，赞一个！！！, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Aug 31 10:48:00 CST 2016, time=2016-08-31, status=1, ipAttribution=)]
    2016-08-31 1dd8a7c5m95(暂无匿称)

    学习了，赞一个！！！

    0

  7. 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createdName=zhaozhouchifen, createdTime=Tue Jul 04 00:18:00 CST 2017, time=2017-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1959786, encodeId=5bef1959e8677, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Tue Mar 07 07:18:00 CST 2017, time=2017-03-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108231, encodeId=1dac108231ad, content=学习了，赞一个！！！, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Aug 31 10:55:00 CST 2016, time=2016-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108223, encodeId=c8a51082230b, content=学习了，赞一个！！！, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Aug 31 10:50:00 CST 2016, time=2016-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108214, encodeId=a0b910821459, content=学习了，赞一个！！！, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Aug 31 10:49:00 CST 2016, time=2016-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108217, encodeId=0fdf10821e41, content=学习了，赞一个！！！, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Aug 31 10:49:00 CST 2016, time=2016-08-31, status=1, ipAttribution=), 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createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Aug 31 10:48:00 CST 2016, time=2016-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108208, encodeId=1a75108208a4, content=学习了，赞一个！！！, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Aug 31 10:48:00 CST 2016, time=2016-08-31, status=1, ipAttribution=)]
    2016-08-31 1dd8a7c5m95(暂无匿称)

    学习了，赞一个！！！

    0

  8. 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createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Aug 31 10:48:00 CST 2016, time=2016-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108208, encodeId=1a75108208a4, content=学习了，赞一个！！！, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Aug 31 10:48:00 CST 2016, time=2016-08-31, status=1, ipAttribution=)]
    2016-08-31 1dd8a7c5m95(暂无匿称)

    学习了，赞一个！！！

    0

  9. 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    2016-08-31 1dd8a7c5m95(暂无匿称)

    学习了，赞一个！！！

    0

  10. 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    2016-08-31 1dd8a7c5m95(暂无匿称)

    学习了，赞一个！！！

    0

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