Neurology:原发性脑出血脑卒中后癫痫风险因素

2017-05-07 zhangfan MedSci原创

原发性脑出血后的长期幸存者,皮层下血肿位置与癫痫史增加患者卒中后癫痫的发病风险

近日研究人员就原发性脑出血(PICH)卒中癫痫(PSE)的特征及诱发因素开展研究。

研究对于1993年至2008年间芬兰原发性脑出血患者资料进行回顾性研究。研究采用Cox比例风险回归模型评估PSE发生率与性别、年龄、入院时格拉斯哥昏迷评分(GCS)、血肿部位和体积、癫痫发作史及其他可能的危险因素之间的关系。

研究涉及了615名原发性脑出血患者,其中83人(13.5%)发生卒中后癫痫。在原发性脑出血后第一年,新发卒中后癫痫的累积发病率为6.8%。在单变量分析中,PSE的危险因素包括癫痫史、皮层下血肿位置、血肿体积、血肿清除术与入院时GCS评分,小脑幕下血肿位置或高血压与PSE不相关。多变量分析发现,皮下血肿位置(HR 2.27, 95% CI 1.35-3.81, p < 0.01)及癫痫史(HR 3.63, 95% CI 1.99-6.64, p < 0.01)为独立风险因素,高血压与与PSE不相关(HR 0.54, 0.35-0.84, p < 0.01)。

研究表明,对于原发性脑出血后的长期幸存者,皮层下血肿位置与癫痫史增加患者卒中后癫痫的发病风险。

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    2017-11-29 yinhl1978
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  5. 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channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/PiajxSqBRaEJicFGXtYqfjGiaibNdjOiaRgkexnXiciaDeXaLiaKicovcicDugdYwRPSnQj3FlfXBwVLB5ANB9PGFyB0kraQ/0, createdBy=35b01663265, createdName=1ddf3e1dm99(暂无匿称), createdTime=Sun May 07 09:52:04 CST 2017, time=2017-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=194908, encodeId=04e919490830, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Sun May 07 08:41:57 CST 2017, time=2017-05-07, status=1, ipAttribution=), 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    2017-05-08 大爰

    实用的知识学习并分享

    0

  6. 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channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/PiajxSqBRaEJicFGXtYqfjGiaibNdjOiaRgkexnXiciaDeXaLiaKicovcicDugdYwRPSnQj3FlfXBwVLB5ANB9PGFyB0kraQ/0, createdBy=35b01663265, createdName=1ddf3e1dm99(暂无匿称), createdTime=Sun May 07 09:52:04 CST 2017, time=2017-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=194908, encodeId=04e919490830, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Sun May 07 08:41:57 CST 2017, time=2017-05-07, status=1, ipAttribution=), 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    2017-05-07 CAOJGSZ

    是否发生癫痫还是要看原始出血部位的!

    0

  7. 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attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUEWmBkP7d4ib2OPTVSicoWCYiaXGfR6R78FNLwmPXO87NTiaZhgicuBaxhspKCXFmgAribspic0CZIrbca/0, createdBy=85341432978, createdName=CAOJGSZ, createdTime=Sun May 07 15:56:33 CST 2017, time=2017-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=195012, encodeId=c9c61950124d, content=癫痫的发病和位置有关吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/icyLhIGqru6gIknBJqfuPhbPwBo0yCebU4qpdSwzpBA1WFXMEUicoTnJDickpj9Ve1cUdNjjTiaDXmpXL47LYh3DdYkPOA2kddyZ/0, createdBy=508c2054450, createdName=solarjin, createdTime=Sun May 07 12:23:28 CST 2017, time=2017-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=194937, encodeId=c4ce19493e90, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/PiajxSqBRaEJicFGXtYqfjGiaibNdjOiaRgkexnXiciaDeXaLiaKicovcicDugdYwRPSnQj3FlfXBwVLB5ANB9PGFyB0kraQ/0, createdBy=35b01663265, createdName=1ddf3e1dm99(暂无匿称), createdTime=Sun May 07 09:52:04 CST 2017, time=2017-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=194908, encodeId=04e919490830, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Sun May 07 08:41:57 CST 2017, time=2017-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=194902, encodeId=b332194902b7, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuGx0Nj1tUEG8bCiclXBNCCfjGSeFLCtppUMLTdyCtkvyjxxXViaDnQv43w5VAuic6FGPuCicSgnNKBc3/0, createdBy=21f41994764, createdName=阿吴, createdTime=Sun May 07 08:35:03 CST 2017, time=2017-05-07, status=1, ipAttribution=)]
    2017-05-07 solarjin

    癫痫的发病和位置有关吧

    0

  8. 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channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/PiajxSqBRaEJicFGXtYqfjGiaibNdjOiaRgkexnXiciaDeXaLiaKicovcicDugdYwRPSnQj3FlfXBwVLB5ANB9PGFyB0kraQ/0, createdBy=35b01663265, createdName=1ddf3e1dm99(暂无匿称), createdTime=Sun May 07 09:52:04 CST 2017, time=2017-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=194908, encodeId=04e919490830, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Sun May 07 08:41:57 CST 2017, time=2017-05-07, status=1, ipAttribution=), 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    2017-05-07 1ddf3e1dm99(暂无匿称)

    学习了谢谢分享

    0

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channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/PiajxSqBRaEJicFGXtYqfjGiaibNdjOiaRgkexnXiciaDeXaLiaKicovcicDugdYwRPSnQj3FlfXBwVLB5ANB9PGFyB0kraQ/0, createdBy=35b01663265, createdName=1ddf3e1dm99(暂无匿称), createdTime=Sun May 07 09:52:04 CST 2017, time=2017-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=194908, encodeId=04e919490830, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Sun May 07 08:41:57 CST 2017, time=2017-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=194902, encodeId=b332194902b7, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuGx0Nj1tUEG8bCiclXBNCCfjGSeFLCtppUMLTdyCtkvyjxxXViaDnQv43w5VAuic6FGPuCicSgnNKBc3/0, createdBy=21f41994764, createdName=阿吴, createdTime=Sun May 07 08:35:03 CST 2017, time=2017-05-07, status=1, ipAttribution=)]
    2017-05-07 榄枷檬

    谢谢分享

    0

  10. 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    2017-05-07 阿吴

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