Dig Dis Sci: 年轻人睡眠障碍也会导致功能性消化不良患病率增加

2021-10-09 MedSci原创 MedSci原创

功能性消化不良 (FD) 虽然不是一种器质性病变,但仍然非常影响人们的生活质量。其特征是上腹部疼痛、上腹部烧灼感、早饱或餐后饱胀等腹部不适。

      功能性消化不良 (FD) 虽然不是一种器质性病变,但仍然非常影响人们的生活质量。其特征是上腹部疼痛、上腹部烧灼感、早饱或餐后饱胀等腹部不适。FD根据罗马III共识分为两个亚组:上腹痛综合征(EPS)和餐后窘迫综合征(PDS);这两种类型都会降低人们的生活质量并限制社交生活。多数欧洲和美国的研究都发现睡眠障碍与 FD 之间存在正相关关系,睡眠障碍的严重程度也与 FD 的症状严重程度呈正相关。但是在亚洲人群中,睡眠障碍与 FD 之间的关联仍不清楚。因此,本项研究的主要目的是调查日本年轻人中睡眠障碍与 FD 的关系。

 

      研究人员以8923名大学生为研究对象。患有 FD 的受试者被进一步分类为患有餐后窘迫综合征 (PDS) 或上腹痛综合征 (EPS)的两组。所有受试者均完成了自我报告的问卷调查,用来评估自我报告的睡眠持续时间、睡眠障碍、入睡困难、深度睡眠障碍、夜间觉醒、早醒和白天嗜睡的情况。

 

      研究结果显示:FD 的患病率为1.9%。所有类型的睡眠障碍均与 FD 独立呈正相关(总睡眠障碍:OR 4.11 [95% CI:2.89-5.78],入睡困难:OR 3.97 [95% CI:2.53-6.01],深度睡眠障碍:OR 4.85 [95% CI: 3.06–7.40],夜间觉醒:OR 4.35 [95% CI: 1.90–8.67],早醒:OR 4.50 [95% CI: 1.97–8.97],白天嗜睡:OR 2.83 95% 置信区间:1.25–5.56])。虽然夜间觉醒和白天嗜睡与 EPS 无关,但其他类型的睡眠障碍与 EPS 和 PDS 独立正相关。

 

       由此, 研究人员得出结论:睡眠障碍与年轻人的 FD 患病率呈独立正相关,虽然夜间觉醒和白天嗜睡与 EPS 无关;但是其他类型的睡眠障碍均与 EPS 和 PDS 独立正相关。

 

 

原始出处:

Yasunori Yamamoto. Et al. Positive Association Between Sleep Disturbance and Prevalence of Functional Dyspepsia in Japanese Young People. Digestive Diseases and Sciences.2021.

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    2021-10-25 ms8000001370942354

    学习了

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    2021-10-11 ms2000000182667314

    学习了

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    2021-10-11 朵小朵朵

    学习了

    0

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    2021-10-11 huihui0728
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    2021-10-11 yangzi3y

    涨知识了

    0

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