Clin Nutr:血糖控制欠佳的糖尿病患者试试低碳水化合物饮食

2016-08-06 Mechront 译 MedSci原创

目的:低碳水化合物饮食(LCD)对2型糖尿病(T2DM)患者有没有益处?研究者进行了一项研究,比较LCD和热量限制饮食(CRD)对T2DM患者的有效性和安全性。方法:这项前瞻性、随机、开放标签的研究纳入了66例T2DM患者,其HbA1c>7.5%;随机分为130克/天 LCD组(n = 33)或CRD组(n = 33)。在基线、1、2、4和6个月时,患者接受CRD或LCD个人营养教育30分钟。CR

目的:低碳水化合物饮食(LCD)对2型糖尿病(T2DM)患者有没有益处?研究者进行了一项研究,比较LCD和热量限制饮食(CRD)对T2DM患者的有效性和安全性。

方法:这项前瞻性、随机、开放标签的研究纳入了66例T2DM患者,其HbA1c>7.5%;随机分为130克/天 LCD组(n = 33)或CRD组(n = 33)。在基线、1、2、4和6个月时,患者接受CRD或LCD个人营养教育30分钟。CRD的组患者被建议保持热量平衡的营养素摄入量(每天摄入的热量为28×理想体重)。LCD患者则被建议保持130克/天的碳水化合物的摄入量,没有其他特定的限制。在基线和6个月后,对每一名患者进行相关参数的测量评估;主要终点是从基线到研究结束患者的HbA1c变化。

结果:CRD组和LCD患者的基线BMI和HbA1c分别为26.5 (24.6-30.1)kg/m2和8.3 (8.0-9.3)%、26.7 (25.0-30.0)kg/m2和8.0 (7.6-8.9)%。研究结束时,LCD组患者的HbA1c下降-0.65 (-1.53 to -0.10) %;而CRD组的变化为0.00 (-0.68 to 0.40) %(p < 0.01)。此外,LCD组BMI下降幅度[-0.58 (-1.51 to -0.16) kg/m2]也大于CRD组(p = 0.03)。

结论:对血糖控制欠佳的T2DM患者,6个月130克/天的LCD可降低HbA1c和BMI。对不能坚持CRD的患者而言,LCD是T2DM患者的潜在有益的营养治疗。

原始出处:

Sato J.et al.A randomized controlled trial of 130 g/day low-carbohydrate diet in type 2 diabetes with poor glycemic control.Clin Nutr. 2016 Jul 18. pii: S0261-5614(16)30169-8. doi: 10.1016/j.clnu.2016.07.003

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    2016-09-20 1e10c84am36(暂无匿称)

    文章很好,非常有益

    0

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    2016-09-12 舒心和人

    糖尿病患者的饮食及运动指导非常重要,合理膳食是控制好血糖的基础

    0

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  4. 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createdTime=Mon Aug 08 11:26:00 CST 2016, time=2016-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96713, encodeId=ff0d96e1399, content=天天学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151005/IMG5612955936CFA7964.jpg, createdBy=18621654109, createdName=Guoxj3234, createdTime=Sun Aug 07 11:58:00 CST 2016, time=2016-08-07, status=1, ipAttribution=)]
    2016-08-11 木水晶

    按中国人的体质来说,低碳水化合物饮食确实有利于血糖控制!

    0

  5. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26296, encryptionId=c2462629612, topicName=低碳水化合物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=医者仁心, createdTime=Mon Aug 08 11:26:00 CST 2016, time=2016-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1464346, encodeId=4f05146434636, content=<a href='/topic/show?id=9b04641580e' target=_blank style='color:#2F92EE;'>#水化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64158, encryptionId=9b04641580e, topicName=水化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f1276671681, createdName=yuanming9, createdTime=Mon Aug 08 11:26:00 CST 2016, time=2016-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474030, encodeId=4d6f14e403018, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Mon Aug 08 11:26:00 CST 2016, time=2016-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1596217, encodeId=eacf159621e4a, content=<a href='/topic/show?id=9d0e2629e5c' target=_blank style='color:#2F92EE;'>#低碳水化合物饮食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26297, encryptionId=9d0e2629e5c, topicName=低碳水化合物饮食)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=713a18344324, createdName=wodejia-dayu, createdTime=Mon Aug 08 11:26:00 CST 2016, time=2016-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96713, encodeId=ff0d96e1399, content=天天学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151005/IMG5612955936CFA7964.jpg, createdBy=18621654109, createdName=Guoxj3234, createdTime=Sun Aug 07 11:58:00 CST 2016, time=2016-08-07, status=1, ipAttribution=)]
    2016-08-08 yuanming9
  8. 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Sep 12 22:24:00 CST 2016, time=2016-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1906315, encodeId=06c81906315d2, content=<a href='/topic/show?id=7795334e220' target=_blank style='color:#2F92EE;'>#化合物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33472, encryptionId=7795334e220, topicName=化合物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=267e204, createdName=wangyang7958, createdTime=Sun Aug 07 19:26:00 CST 2016, time=2016-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=97432, encodeId=3cae9e4326e, content=按中国人的体质来说,低碳水化合物饮食确实有利于血糖控制!, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/DYAIOgq83er7gGJY7ibia1wDTTwTL7vXbqvekMBTHAsd3KZ7btXM9tnHuicI2LdxJtIiccXeDCiaTvzkwMuribZ9oHVA/0, createdBy=c7b81713099, createdName=木水晶, createdTime=Thu Aug 11 11:58:00 CST 2016, time=2016-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1272929, encodeId=433212e29297e, content=<a href='/topic/show?id=2f468983351' target=_blank style='color:#2F92EE;'>#血糖控制#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89833, encryptionId=2f468983351, topicName=血糖控制)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ef84111, createdName=whlxd, createdTime=Mon Aug 08 11:26:00 CST 2016, time=2016-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1345120, encodeId=742e1345120be, content=<a href='/topic/show?id=c2462629612' target=_blank style='color:#2F92EE;'>#低碳水化合物#</a>, 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  9. 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createdTime=Mon Aug 08 11:26:00 CST 2016, time=2016-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96713, encodeId=ff0d96e1399, content=天天学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151005/IMG5612955936CFA7964.jpg, createdBy=18621654109, createdName=Guoxj3234, createdTime=Sun Aug 07 11:58:00 CST 2016, time=2016-08-07, status=1, ipAttribution=)]
  10. 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createdTime=Mon Aug 08 11:26:00 CST 2016, time=2016-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96713, encodeId=ff0d96e1399, content=天天学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151005/IMG5612955936CFA7964.jpg, createdBy=18621654109, createdName=Guoxj3234, createdTime=Sun Aug 07 11:58:00 CST 2016, time=2016-08-07, status=1, ipAttribution=)]
    2016-08-07 Guoxj3234

    天天学习

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