慢性肾脏病3期糖尿病肾病与非糖尿病肾病患者贫血特点及影响因素分析

2013-11-29 佚名 医学论坛网

近日,河南省濮阳市中医医院肾病科研究人员发表论文,旨在评估慢性肾脏病3期(CKD3)糖尿病肾病(DN)与非糖尿病肾病患者之间贫血特点的差异及影响因素。研究指出,CKD3糖尿病肾病患者的贫血程度较非糖肾组严重,其贫血的发生与低蛋白血症、糖尿病肾外因素及铁代谢异常密切相关。该文发表在2013年第09期《中国中西医结合肾病杂志》上。 选取2012年2月~2013年5月在上海市第六人民医院肾内科住院的C

近日,河南省濮阳市中医医院肾病科研究人员发表论文,旨在评估慢性肾脏病3期(CKD3)糖尿病肾病(DN)与非糖尿病肾病患者之间贫血特点的差异及影响因素。研究指出,CKD3糖尿病肾病患者的贫血程度较非糖肾组严重,其贫血的发生与低蛋白血症、糖尿病肾外因素及铁代谢异常密切相关。该文发表在2013年第09期《中国中西医结合肾病杂志》上。

选取2012年2月~2013年5月在上海市第六人民医院肾内科住院的CKD3患者,其中糖尿病肾病42例,非糖尿病肾病患者49例,检测患者红细胞计数(RBC)、血红蛋白(Hb)、总蛋白(TP)、白蛋白(Alb)、促红细胞生长素(EPO)、铁蛋白、总铁结合力、血清铁、叶酸、维生素B12、肌酐、尿素氮、钙、磷、甲状旁腺素、25羟维生素D3等指标进行对比分析。

42例CKD3期糖尿病肾病患者总的贫血发生率为67%,49例非糖肾组患者总的贫血发生率为39%。糖尿病肾病组红细胞计数、血红蛋白、白蛋白、血清铁均明显低于非糖肾组,组间差异具有统计学意义(P<0.05),DN组促红细胞生长素水平高于非DN组(P<0.05)。

原文出处

张少崇,程东生,汪年松.慢性肾脏病3期糖尿病肾病与非糖尿病肾病患者贫血特点及影响因素分析. 中国中西医结合肾病杂志 2013, 14(9)

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