AJG:吸烟与非酒精性脂肪性肝病发生风险之间的关系

2019-03-23 不详 MedSci原创

目前研究人员对于吸烟在非酒精性脂肪性肝病(NAFLD)发展中的作用仍存在争议。因此,本项研究旨在根据吸烟状况和尿中可替宁水平与NAFLD事件的发生风险进行评估。

背景及目的: 
目前研究人员对于吸烟在非酒精性脂肪性肝病(NAFLD)发展中的作用仍存在争议。因此,本项研究旨在根据吸烟状况和尿中可替宁水平与NAFLD事件的发生风险进行评估。

方法: 
研究人员对基线时没有NAFLD的199468名韩国成年人进行了一项队列研究,平均随访时间4.1年。使用超声判断是否存在脂肪肝。使用NAFLD纤维化评分(NFS)(一种非侵入性纤维化标记物)评估NAFLD严重性。

结果:
研究结果显示在1070991人年的随访期间中,45409名患者出现了NAFLD。自我报告的吸烟状态,尿中可替宁水平与NAFLD风险增加显着相关。吸烟数量也与NAFLD的中度或高度纤维化评分的风险增加有关。

结论:
目前吸烟状态,吸烟数量和尿中可替宁水平与NAFLD事件风险呈正相关关系,表明吸烟有助于NAFLD的发展。

原始出处:
Jung, Hyun-Suk. Et al. Smoking and the Risk of Non-Alcoholic Fatty Liver Disease. American Journal of Gastroenterology.2019.

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    2020-01-21 minzju5052
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    2020-03-08 qjddjq
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    2019-03-23 王秀

    学习了,涨知识了!

    0