脑血管疾病影像学诊断指南要点汇总

2015-06-29 大鹏 整理 医学论坛网

 在中国卒中学会第一届学术年会暨天坛国际脑血管病会议上,南京大学医学院附属鼓楼医院神经科徐运教授介绍了脑血管疾病影像学诊断指南。一、脑成像技术CT诊断推荐要点1.CT是脑出血的首选检查。(A级证据,Ⅰ级推荐)2.CT为蛛网膜出血的首选诊断检查。(A级证据,Ⅰ级推荐)3.CT是急性缺血性卒中的首选急诊检查。(A级证据,Ⅰ级推荐)4.在静脉rt

 在中国卒中学会第一届学术年会暨天坛国际脑血管病会议上,南京大学医学院附属鼓楼医院神经科徐运教授介绍了脑血管疾病影像学诊断指南。

一、脑成像技术CT诊断推荐要点

1.CT是脑出血的首选检查。(A级证据,Ⅰ级推荐)

2.CT为蛛网膜出血的首选诊断检查。(A级证据,Ⅰ级推荐)

3.CT是急性缺血性卒中的首选急诊检查。(A级证据,Ⅰ级推荐)

4.在静脉rtPA治疗前,应完成NECT排除脑出血,并明确是否存在低密度缺血灶。(A级证据,Ⅰ级推荐)

5.CT可作为脑静脉窦血栓形成的初始常规检查;若发现大脑皮层及皮层下区不明原因水肿或脑出血,应考虑血栓形成的可能性,但此时由于CT低敏感性及假阳性率,不推荐首选。(B级证据,Ⅱ级推荐)

二、脑成像技术MRI推荐要点

1.在脑卒中症状出现的6小时内,弥散加权成像(DWI)的敏感性及特异性优于CT及其他MRI检查方式,有助于早期缺血性脑卒中诊断。(A级证据,Ⅰ级推荐)

2.若患者症状超过3个小时,建议完善MRI-DWI或CTA-SI、血管成像及灌注成像,这点对于动脉溶栓或取栓患者尤为重要。(A级证据,Ⅰ级推荐)

3.DWI可评估大脑前部卒中严重程度和最终梗死面积(B级证据,Ⅱ级推荐),但不推荐于基底区行此检测(C级证据)。

4. MRI-DWI有助于预测最终梗死面积的大小(B级证据,Ⅱ级推荐)及临床预后(C级证据,Ⅱ级推荐)

5.对于脑卒中亚急性期、慢性期及缺血后出血,MRI检查明显优于CT。(B级证据,Ⅱ级推荐)

6.MRI的GRE序列可于早期诊断脑出血,同时在诊断新发或陈旧微出血灶方面,明显优于CT。(B级证据,Ⅱ级推荐)

7.对于MRI发现但CT未显示的微出血灶,目前不作为静脉溶栓禁忌症。(B级证据,Ⅱ级推荐)

三、脑血管成像技术推荐要点

1.CTA在动脉瘤诊断方面具有高敏感性及特异性,可作为未接受DSA患者的首选检查。(B级证据,Ⅱ级推荐)

2.CTA是颅内动脉瘤引起的自发性蛛网膜出血的首选检查,CT灌注成像(CTP)具有迟发性出血诊断价值。(B级证据,Ⅱ级推荐)

3.对于CTA阴性的蛛网膜下腔出血患者,建议完善DSA。(B级证据,Ⅱ级推荐)

4.CE-MRA适合于动脉夹层的无创性筛查。(A级证据,Ⅰ级推荐)

5.在诊断脑静脉窦血栓方面,MRI及MRV是目前准确、敏感的首要检查方式,也是随访的主要检查方式。但对于单独静脉血栓又无静脉内血栓影像改变的患者,仍需进一步DSA检查。(A级证据,Ⅰ级推荐)

6.DSA是脑静脉窦血栓形成的金标准,可作为MRI及MRV的补充手段。(A级证据,Ⅰ级推荐)

7.DSA是诊断颅内动脉瘤的金标准,是首要的推荐。(A级证据,Ⅰ级推荐)

8.DSA是诊断颅内动脉狭窄的金标准。(A级证据,Ⅰ级推荐)

四、脑灌注成像技术指南要点

1.CTP联合CTA检测可评估血管狭窄,根据TTP延迟等数据预测TIA危险分级。(B级证据,Ⅱ级推荐)

2.CTP可辅助评价周围血肿血流灌注情况。(B级证据,Ⅱ级推荐)

3.CTP可诊断蛛网膜下腔出血患者迟发性出血。(B级证据,Ⅱ级推荐)

4.CTP可辅助临床区分永久性梗死和可逆性缺血半暗带存在,有助于溶栓和预后判断。(B级证据,Ⅱ级推荐)

5.MRP识别灌注区域及缺血半暗带区域略优于CTP,有助于扩大溶栓时间窗。(B级证据,Ⅱ级推荐)

6.MRP可辅助鉴别诊断TIA及小卒中。(B级证据,Ⅱ级推荐)

五、其他技术推荐要点

1.扩散张量成像(DTI)有助于神经变性程度判断,预测患者运动功能转归。(B级证据,Ⅱ级推荐)

2.BOLD序列可评估神经血管活动,以及脑梗死病灶的活性。(B级证据,Ⅱ级推荐)

3.磁共振弹性成像(MRE)可鉴别诊断卒中与脑肿瘤。(C级证据,Ⅲ级推荐)

4.磁共振波谱(MRS)可早期评价缺血脑组织代谢改变、缺血组织损伤严重度,判断患者预后及疗效。(C级证据)

5. 磁敏感加权成像(SWI)可早期诊断脑出血、缺血性脑卒中出血转化、微出血及静脉血栓形成,从而提供缺血性脑卒中血流动力学信息。(B级证据,Ⅱ级推荐)

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    2017-04-08 ylzr123

    感谢小编为我们精心准备了如此精辟的精神大餐,小编辛苦了!不错的指南,为我们探讨研究提供了方针,给点个赞了!

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=185894, encodeId=28b0185894d4, content=感谢小编为我们精心准备了如此精辟的精神大餐,小编辛苦了!不错的指南,为我们探讨研究提供了方针,给点个赞了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sat Apr 08 06:22:43 CST 2017, time=2017-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=174902, encodeId=7bc41e4902da, content=获益良多 谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=63101979945, createdName=美景, createdTime=Wed Feb 08 08:24:40 CST 2017, time=2017-02-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=171105, encodeId=47511e1105d3, content=谢谢,非常有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Wed Jan 18 12:48:54 CST 2017, time=2017-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=34546, encodeId=a148345463b, content=希望能有更新的突破吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=332823945, createdName=hlycom3356, createdTime=Wed Aug 05 12:21:00 CST 2015, time=2015-08-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=34545, encodeId=c0823454547, content=这些汇总很靠谱, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=332823945, createdName=hlycom3356, createdTime=Wed Aug 05 12:20:00 CST 2015, time=2015-08-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2060637, encodeId=c7cd206063e06, content=<a href='/topic/show?id=0d1f50290a8' target=_blank style='color:#2F92EE;'>#影像学诊断#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50290, encryptionId=0d1f50290a8, topicName=影像学诊断)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fa4f352, createdName=chenlianhui, createdTime=Tue Oct 27 18:39:00 CST 2015, time=2015-10-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=32950, encodeId=0b0432950f2, content=Du exile, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a4381603761, createdName=feijie999, createdTime=Thu Jul 16 23:54:00 CST 2015, time=2015-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=32610, encodeId=1e593261088, content=很不错的指导意见, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9c501632215, createdName=1dd8ea20m15(暂无匿称), createdTime=Mon Jul 13 17:13:00 CST 2015, time=2015-07-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=31752, encodeId=09c531e52ed, content=很好的指南, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d0f31631005, createdName=保守主义, createdTime=Thu Jul 09 07:16:00 CST 2015, time=2015-07-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=30865, encodeId=3c8c3086510, content=多学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=863c1626303, createdName=1dd7bf29m39(暂无匿称), createdTime=Sun Jul 05 17:02:00 CST 2015, time=2015-07-05, status=1, ipAttribution=)]
    2017-02-08 美景

    获益良多 谢谢

    0

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    2017-01-18 虈亣靌

    谢谢,非常有用

    0

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    2015-08-05 hlycom3356

    希望能有更新的突破吧

    0

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    2015-08-05 hlycom3356

    这些汇总很靠谱

    0

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    2015-07-16 feijie999

    Du exile

    0

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    2015-07-13 1dd8ea20m15(暂无匿称)

    很不错的指导意见

    0

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    2015-07-09 保守主义

    很好的指南

    0

  10. [GetPortalCommentsPageByObjectIdResponse(id=185894, encodeId=28b0185894d4, content=感谢小编为我们精心准备了如此精辟的精神大餐,小编辛苦了!不错的指南,为我们探讨研究提供了方针,给点个赞了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sat Apr 08 06:22:43 CST 2017, time=2017-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=174902, encodeId=7bc41e4902da, content=获益良多 谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=63101979945, createdName=美景, createdTime=Wed Feb 08 08:24:40 CST 2017, time=2017-02-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=171105, encodeId=47511e1105d3, content=谢谢,非常有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Wed Jan 18 12:48:54 CST 2017, time=2017-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=34546, encodeId=a148345463b, content=希望能有更新的突破吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=332823945, createdName=hlycom3356, createdTime=Wed Aug 05 12:21:00 CST 2015, time=2015-08-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=34545, encodeId=c0823454547, content=这些汇总很靠谱, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=332823945, createdName=hlycom3356, createdTime=Wed Aug 05 12:20:00 CST 2015, time=2015-08-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2060637, encodeId=c7cd206063e06, content=<a href='/topic/show?id=0d1f50290a8' target=_blank style='color:#2F92EE;'>#影像学诊断#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50290, encryptionId=0d1f50290a8, topicName=影像学诊断)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fa4f352, createdName=chenlianhui, createdTime=Tue Oct 27 18:39:00 CST 2015, time=2015-10-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=32950, encodeId=0b0432950f2, content=Du exile, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a4381603761, createdName=feijie999, createdTime=Thu Jul 16 23:54:00 CST 2015, time=2015-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=32610, encodeId=1e593261088, content=很不错的指导意见, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9c501632215, createdName=1dd8ea20m15(暂无匿称), createdTime=Mon Jul 13 17:13:00 CST 2015, time=2015-07-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=31752, encodeId=09c531e52ed, content=很好的指南, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d0f31631005, createdName=保守主义, createdTime=Thu Jul 09 07:16:00 CST 2015, time=2015-07-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=30865, encodeId=3c8c3086510, content=多学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=863c1626303, createdName=1dd7bf29m39(暂无匿称), createdTime=Sun Jul 05 17:02:00 CST 2015, time=2015-07-05, status=1, ipAttribution=)]
    2015-07-05 1dd7bf29m39(暂无匿称)

    多学习

    0