PLoS One:没有B超的地区,怀孕了如何估计胎龄

2015-05-10 MedSci译 MedSci原创

对孕周的准确评估需要全面的孕期保健数据,并且是研究早产原因的一个重要组成部分。在工业化国家,可以通过怀孕早期胎儿的生物评估数据如B超下头臀长、双顶径、NT值等帮助医师及孕妇确定胎儿胎龄。但是在资源匮乏区域,没有B超装备、没有规范的产前诊断医院等等,均会使这些科学评估胎龄方法变得不切实际,取而代之的则是临床妊娠情况来评估胎龄,但是该种评估方法的精确可靠性仍有待商榷。Karl S等人进行了一项研究,探


对孕周的准确评估需要全面的孕期保健数据,并且是研究早产原因的一个重要组成部分。在工业化国家,可以通过怀孕早期胎儿的生物评估数据如B超下头臀长、双顶径、NT值等帮助医师及孕妇确定胎儿胎龄。但是在资源匮乏区域,没有B超装备、没有规范的产前诊断医院等等,均会使这些科学评估胎龄方法变得不切实际,取而代之的则是临床妊娠情况来评估胎龄,但是该种评估方法的精确可靠性仍有待商榷。Karl S等人进行了一项研究,探究临床评估方法的准确性。

该研究共纳入巴布亚新几内亚农村区域688名单胎妊娠孕妇,研究者根据Ballard评分法计算分娩时孕周或胎龄,收集孕产妇的末次月经日期、第一次随访孕妇时的耻骨联合宫高、孕妇感到胎动时间、以及孕中期孕晚期的胎儿生物测量数据。检测根据时间顺序测量宫高腹围值和纠正末次月经时间评估胎龄该方法的准确度。根据Bland-Altman相关、回归分析,使该预测方法与孕早期B超相比较,并且使用调和平均数和精确度(F-measure)按预测早产能力进行排名。

研究结果显示,超声和临床评估在胎龄估计方面平均相差0-11天 (95% CI: 14-42天)。孕中期超声能最好的预测早产(F-measure: 0.72),神经肌肉的Ballard评分对于早产的预测效果最差(F-measure: 0.17)。在临床评估方法上,根据宫高腹围和末次月经能最好的估计胎龄和预测早产(F-measures 0.35)。根据测量值做出的线性模型可以改善早产预测情况(F-measure: 0.58)。

研究结果表明,没有超声的情况下对孕龄的估计很容易发生重大错误。但是在缺乏超声设备的区域,通过孕期宫高腹围以及末次月经等数据是最可靠有效的临床评估方法。该项研究强调了超声设备在产科领域的重要性以及发展新的方法来估计胎龄的迫切性。

原始出处:

Karl S, Li WSCS, Unger HW, et al. Preterm or not - an evaluation of estimates of gestational age in a cohort of women from rural papua new Guinea. PLoS One. 2015. 10(5): e0124286.

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    2015-05-21 jasonuclear

    连最简单的超声检查,最好在农村也能实现吧。更多的农村孕妇

    0

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    2015-05-15 JinFish

    的确是换个角度

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1740305, encodeId=71581e40305a4, content=<a href='/topic/show?id=f9f383688d0' target=_blank style='color:#2F92EE;'>#胎龄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83688, encryptionId=f9f383688d0, topicName=胎龄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f53c34728820, createdName=ms8538335253054589, createdTime=Mon Dec 14 05:35:00 CST 2015, time=2015-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1789666, encodeId=0d7d1e89666f9, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Mon Jun 15 07:35:00 CST 2015, time=2015-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=24323, encodeId=9bf7243237e, content=连最简单的超声检查,最好在农村也能实现吧。更多的农村孕妇, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160515/IMG57380B859AD1F1019.jpg, createdBy=2c5c1621956, createdName=jasonuclear, createdTime=Thu May 21 07:58:00 CST 2015, time=2015-05-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23559, encodeId=253c2355982, content=的确是换个角度, beContent=null, objectType=article, channel=null, level=null, likeNumber=129, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=36b41624922, createdName=JinFish, createdTime=Fri May 15 07:10:00 CST 2015, time=2015-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23451, encodeId=15e32345122, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=150, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Wed May 13 21:23:00 CST 2015, time=2015-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1618671, encodeId=d86816186e186, content=<a href='/topic/show?id=232f3859c9' target=_blank style='color:#2F92EE;'>#B超#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3859, encryptionId=232f3859c9, topicName=B超)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c57019929498, createdName=ms7524819409032184, createdTime=Tue May 12 05:35:00 CST 2015, time=2015-05-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23135, encodeId=1a96231358e, content=!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=chaie1217, createdTime=Mon May 11 14:04:00 CST 2015, time=2015-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23124, encodeId=a79d2312458, content=有意义, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3yz0JbjHQ7nicJU7lHMOu0Itf3Zv3VBzEvK3k4AFPBXhiaxIRNGVI33GicoRXQEjkaasjdlWKwZuwcyhDP9Jibqt5ct/0, createdBy=f1281613275, createdName=zhouanxiu, createdTime=Mon May 11 00:33:00 CST 2015, time=2015-05-11, status=1, ipAttribution=)]
    2015-05-13 huaxipanxing

    看看

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1740305, encodeId=71581e40305a4, content=<a href='/topic/show?id=f9f383688d0' target=_blank style='color:#2F92EE;'>#胎龄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83688, encryptionId=f9f383688d0, topicName=胎龄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f53c34728820, createdName=ms8538335253054589, createdTime=Mon Dec 14 05:35:00 CST 2015, time=2015-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1789666, encodeId=0d7d1e89666f9, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Mon Jun 15 07:35:00 CST 2015, time=2015-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=24323, encodeId=9bf7243237e, content=连最简单的超声检查,最好在农村也能实现吧。更多的农村孕妇, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160515/IMG57380B859AD1F1019.jpg, createdBy=2c5c1621956, createdName=jasonuclear, createdTime=Thu May 21 07:58:00 CST 2015, time=2015-05-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23559, encodeId=253c2355982, content=的确是换个角度, beContent=null, objectType=article, channel=null, level=null, likeNumber=129, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=36b41624922, createdName=JinFish, createdTime=Fri May 15 07:10:00 CST 2015, time=2015-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23451, encodeId=15e32345122, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=150, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Wed May 13 21:23:00 CST 2015, time=2015-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1618671, encodeId=d86816186e186, content=<a href='/topic/show?id=232f3859c9' target=_blank style='color:#2F92EE;'>#B超#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3859, encryptionId=232f3859c9, topicName=B超)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c57019929498, createdName=ms7524819409032184, createdTime=Tue May 12 05:35:00 CST 2015, time=2015-05-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23135, encodeId=1a96231358e, content=!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=chaie1217, createdTime=Mon May 11 14:04:00 CST 2015, time=2015-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23124, encodeId=a79d2312458, content=有意义, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3yz0JbjHQ7nicJU7lHMOu0Itf3Zv3VBzEvK3k4AFPBXhiaxIRNGVI33GicoRXQEjkaasjdlWKwZuwcyhDP9Jibqt5ct/0, createdBy=f1281613275, createdName=zhouanxiu, createdTime=Mon May 11 00:33:00 CST 2015, time=2015-05-11, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=1740305, encodeId=71581e40305a4, content=<a href='/topic/show?id=f9f383688d0' target=_blank style='color:#2F92EE;'>#胎龄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83688, encryptionId=f9f383688d0, topicName=胎龄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f53c34728820, createdName=ms8538335253054589, createdTime=Mon Dec 14 05:35:00 CST 2015, time=2015-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1789666, encodeId=0d7d1e89666f9, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Mon Jun 15 07:35:00 CST 2015, time=2015-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=24323, encodeId=9bf7243237e, content=连最简单的超声检查,最好在农村也能实现吧。更多的农村孕妇, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160515/IMG57380B859AD1F1019.jpg, createdBy=2c5c1621956, createdName=jasonuclear, createdTime=Thu May 21 07:58:00 CST 2015, time=2015-05-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23559, encodeId=253c2355982, content=的确是换个角度, beContent=null, objectType=article, channel=null, level=null, likeNumber=129, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=36b41624922, createdName=JinFish, createdTime=Fri May 15 07:10:00 CST 2015, time=2015-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23451, encodeId=15e32345122, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=150, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Wed May 13 21:23:00 CST 2015, time=2015-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1618671, encodeId=d86816186e186, content=<a href='/topic/show?id=232f3859c9' target=_blank style='color:#2F92EE;'>#B超#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3859, encryptionId=232f3859c9, topicName=B超)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c57019929498, createdName=ms7524819409032184, createdTime=Tue May 12 05:35:00 CST 2015, time=2015-05-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23135, encodeId=1a96231358e, content=!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=chaie1217, createdTime=Mon May 11 14:04:00 CST 2015, time=2015-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23124, encodeId=a79d2312458, content=有意义, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3yz0JbjHQ7nicJU7lHMOu0Itf3Zv3VBzEvK3k4AFPBXhiaxIRNGVI33GicoRXQEjkaasjdlWKwZuwcyhDP9Jibqt5ct/0, createdBy=f1281613275, createdName=zhouanxiu, createdTime=Mon May 11 00:33:00 CST 2015, time=2015-05-11, status=1, ipAttribution=)]
    2015-05-11 chaie1217

    !!

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1740305, encodeId=71581e40305a4, content=<a href='/topic/show?id=f9f383688d0' target=_blank style='color:#2F92EE;'>#胎龄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83688, encryptionId=f9f383688d0, topicName=胎龄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f53c34728820, createdName=ms8538335253054589, createdTime=Mon Dec 14 05:35:00 CST 2015, time=2015-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1789666, encodeId=0d7d1e89666f9, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Mon Jun 15 07:35:00 CST 2015, time=2015-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=24323, encodeId=9bf7243237e, content=连最简单的超声检查,最好在农村也能实现吧。更多的农村孕妇, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160515/IMG57380B859AD1F1019.jpg, createdBy=2c5c1621956, createdName=jasonuclear, createdTime=Thu May 21 07:58:00 CST 2015, time=2015-05-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23559, encodeId=253c2355982, content=的确是换个角度, beContent=null, objectType=article, channel=null, level=null, likeNumber=129, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=36b41624922, createdName=JinFish, createdTime=Fri May 15 07:10:00 CST 2015, time=2015-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23451, encodeId=15e32345122, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=150, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Wed May 13 21:23:00 CST 2015, time=2015-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1618671, encodeId=d86816186e186, content=<a href='/topic/show?id=232f3859c9' target=_blank style='color:#2F92EE;'>#B超#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3859, encryptionId=232f3859c9, topicName=B超)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c57019929498, createdName=ms7524819409032184, createdTime=Tue May 12 05:35:00 CST 2015, time=2015-05-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23135, encodeId=1a96231358e, content=!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=chaie1217, createdTime=Mon May 11 14:04:00 CST 2015, time=2015-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23124, encodeId=a79d2312458, content=有意义, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3yz0JbjHQ7nicJU7lHMOu0Itf3Zv3VBzEvK3k4AFPBXhiaxIRNGVI33GicoRXQEjkaasjdlWKwZuwcyhDP9Jibqt5ct/0, createdBy=f1281613275, createdName=zhouanxiu, createdTime=Mon May 11 00:33:00 CST 2015, time=2015-05-11, status=1, ipAttribution=)]
    2015-05-11 zhouanxiu

    有意义

    0

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