JAHA:视网膜静脉闭塞对卒中有啥影响?

2016-12-23 haofan MedSci原创

视网膜静脉闭塞是与卒中风险增加相关,尤其是在50岁~69岁之间的受试者中。视网膜静脉闭塞患者进行视网膜静脉闭塞治疗和减少危险因素对卒中风险的影响需要进一步研究。

视网膜静脉闭塞和卒中风险之间的相关性存在较大争议。近日,心血管病领域权威杂志JAHA上发表了一项荟萃分析结果,评估了视网膜静脉闭塞和卒中风险之间的关系。

研究人员检索了PubMed、EMBASE和Cochrane图书馆等数据库,查找了有关视网膜静脉闭塞和卒中风险的队列研究数据。研究者纳入了报告视网膜静脉闭塞与卒中风险之间相关性的调整后相对风险(RR)和95%可信区间(CI)的研究,根据主要特征进行分层分析。共有5篇文章包括了6个前瞻性队列研究的结果,其中471名卒中患者和37,471名参与者被纳入进行Meta分析。

总的来说,对已知的心血管疾病的危险因素进行调整后,在基线水平,相比那些无视网膜静脉闭塞的参与者,视网膜静脉闭塞患者具有更大的脑卒中发病风险(联合RR 1.50,95%CI:1.19-1.90)。


对卒中史进行分层,与卒中相关的结果更明显(RR 1.72,95%CI:1.24-2.37)。在男性(RR 1.20,95%CI:0.96–1.49)和女性(RR 0.93,95%CI:0.64–1.34)受试者中视网膜静脉闭塞与卒中风险无显著意义。

中央视网膜静脉闭塞(RR 1.90,95%CI:1.46–2.48)和分支视网膜静脉闭塞(RR1.79,95%CI:1.18–2.72)均与卒中风险增加相关。对年龄进行分层,研究者发现50~59岁和60~69年这两个年龄段的参与者,视网膜静脉闭塞与卒中风险之间的相关性类似。

由此可见,视网膜静脉闭塞是与卒中风险增加相关,在50岁~69岁之间的受试者中尤其显著。视网膜静脉闭塞患者进行视网膜静脉闭塞治疗和减少危险因素对卒中风险的影响需要进一步研究。

原始出处:

Min Li, et al. Impact of Retinal Vein Occlusion on Stroke Incidence: A Meta‐Analysis.  JAHA.2016;   

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    2017-06-04 fusion
  2. [GetPortalCommentsPageByObjectIdResponse(id=1697404, encodeId=69cf169e40417, content=<a href='/topic/show?id=f2399910109' target=_blank style='color:#2F92EE;'>#静脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99101, encryptionId=f2399910109, topicName=静脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0bc129907796, createdName=fusion, createdTime=Sun Jun 04 17:55:00 CST 2017, time=2017-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=167516, encodeId=06c616e5160f, content=看上去好有道理,我要去做个脑CT看看。, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=551e1942325, createdName=1e0f487cm54(暂无匿称), createdTime=Mon Jan 02 17:24:01 CST 2017, time=2017-01-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=165596, encodeId=815b16559637, content=神经系统疾病,跟耳,眼,大脑相关性强。, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160313/IMG56E50DEC424F44672.jpg, createdBy=ce5b1699635, createdName=Lisa971, createdTime=Sun Dec 25 13:41:26 CST 2016, time=2016-12-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1267362, encodeId=b8cd126e362db, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Sun Dec 25 01:55:00 CST 2016, time=2016-12-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1269843, encodeId=50391269843c5, content=<a href='/topic/show?id=979690e33bd' target=_blank style='color:#2F92EE;'>#视网膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90733, encryptionId=979690e33bd, topicName=视网膜)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=742793, createdName=zutt, createdTime=Sun Dec 25 01:55:00 CST 2016, time=2016-12-25, status=1, ipAttribution=)]
    2017-01-02 1e0f487cm54(暂无匿称)

    看上去好有道理,我要去做个脑CT看看。

    0

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    2016-12-25 Lisa971

    神经系统疾病,跟耳,眼,大脑相关性强。

    0

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    2016-12-25 zhaohui6731
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    2016-12-25 zutt