Diabetes Obes Metabo：二甲双胍对肥胖儿童的影响

2014-12-26 佚名生物谷

根据公布在Diabetes, Obesity and Metabolism杂志上一则研究提示，对于肥胖儿童，二甲双胍似乎可以降低饥饿感和增加饱腹感觉。美国国立卫生研究院Mopelola A. Adeyemo和他的同事对年龄在6至12岁的100名肥胖高胰岛素血症儿童，进行了一项为期6个月的随机、双盲、安慰剂对照试验，以评估二甲双胍对体重和能量平衡的影响，共84名儿童数据可用（45名二甲双胍治

根据公布在Diabetes, Obesity and Metabolism杂志上一则研究提示，对于肥胖儿童，二甲双胍似乎可以降低饥饿感和增加饱腹感觉。

美国国立卫生研究院Mopelola A. Adeyemo和他的同事对年龄在6至12岁的100名肥胖高胰岛素血症儿童，进行了一项为期6个月的随机、双盲、安慰剂对照试验，以评估二甲双胍对体重和能量平衡的影响，共84名儿童数据可用（45名二甲双胍治疗者和39名安慰剂治疗）。

研究人员发现，二甲双胍治疗与平均能量摄入基线显著减少相关，二甲双胍显著降低饥饿率，并增加了饱腹感（P = 0.013和0.01）。总之，我们发现，二甲双胍治疗的减肥效果可能与它减少肥胖高胰岛素血症儿童能量摄入的能力相关。

因此二甲双胍可以作为饮食，运动和行为治疗的辅助，对于肥胖儿童的控制是非常有用的。

原始出处

Adeyemo MA1, McDuffie JR, Kozlosky M, Krakoff J, Calis KA, Brady SM, Yanovski JA.Effects of Metformin on Energy Intake and Satiety in Obese Children.Diabetes Obes Metab. 2014 Dec 8

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2015-11-02 ms5439512287675881

#BET#

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2015-12-03 一闲

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2015-09-15 minlingfeng

#肥胖儿童#

40 0
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2015-01-04 guojianrong

#Meta#

33 0
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2015-06-08 ljjj1053

好好学习学习

99 0
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2015-03-18 ms9608593228839890

#DIA#

23 0
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2015-08-20 木头人513

#Diabetes#

31 0
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2014-12-28 闆锋旦

#ABO#

34 0

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Diabetes Obes Metabo：二甲双胍对肥胖儿童的影响

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