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Neurology：水痘带状疱疹病毒性血管病易误诊为颞动脉炎

2013-06-06 Neurology dxy

巨细胞动脉炎颞动脉炎
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五例颞动脉炎活检阴性患者的免疫组化结果 颞动脉炎易出现视力异常，为神经科急症之一。为评价临床怀疑但活检阴性的巨细胞动脉炎(GCA)患者发生水痘带状疱疹病毒(VZV)感染的发生率，来自Colorado大学的Nagel MA等医师分析了已存档的临床怀疑但活检阴性的巨细胞动脉炎患者的巨细胞活检标本，重新进行VZV抗原的检测。研究结果显示：巨细胞动脉炎患者出现的临床及实验室检查异常症状谱，在多灶性VZV


五例颞动脉炎活检阴性患者的免疫组化结果

颞动脉炎易出现视力异常，为神经科急症之一。为评价临床怀疑但活检阴性的巨细胞动脉炎(GCA)患者发生水痘带状疱疹病毒(VZV)感染的发生率，来自Colorado大学的Nagel MA等医师分析了已存档的临床怀疑但活检阴性的巨细胞动脉炎患者的巨细胞活检标本，重新进行VZV抗原的检测。研究结果显示：巨细胞动脉炎患者出现的临床及实验室检查异常症状谱，在多灶性VZV血管病患者均可出现。

该研究对比分析了GCA病理阴性患者及正常对照组经过福尔马林固定、石蜡包埋的颞动脉标本，采用免疫组化的方法检测水痘带状疱疹病毒及单纯疱疹病毒-1(HSV-1)抗原。

通过免疫组化分析发现，在24例临床怀疑颞动脉炎但病理活检阴性的患者中，有5例(21%)患者显示VZV抗原阳性，但HSV-1阴性。13例正常对照组中未发现 VZV或HSV-1抗原阳性的患者。在五例颞动脉VZV阳性的患者中，临床及实验室检查均提示颞动脉炎的诊断，而且都出现视觉异常。

巨细胞动脉炎患者出现的临床及实验室检查异常症状谱，在多灶性VZV血管病患者均可出现。

Multifocal VZV vasculopathy with temporal artery infection mimics giant cell arteritis.
Abstract
OBJECTIVE: To address the incidence of varicella-zoster virus (VZV) infection in patients with biopsy-negative giant cell arteritis (GCA), we examined archived biopsy-negative temporal arteries from subjects with clinically suspected GCA for the presence of VZV antigen.
METHODS: Formalin-fixed, paraffin-embedded temporal arteries that were pathologically negative for GCA and normal temporal arteries were analyzed immunohistochemically for VZV and herpes simplex virus-1 (HSV-1) antigen.
RESULTS: Five (21%) of 24 temporal arteries from patients who were clinically suspect but biopsy negative for GCA revealed VZV but not HSV-1 by immunohistochemical analysis. Thirteen normal temporal arteries did not contain VZV or HSV-1 antigen. All 5 subjects whose temporal arteries contained VZV antigen presented with clinical and laboratory features of GCA and early visual disturbances.
CONCLUSION: Multifocal VZV vasculopathy can present with the full spectrum of clinical features and laboratory abnormalities characteristically seen in GCA.

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    2013-10-23 sunylz

    #颞动脉#

    0

  2. 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    2013-08-18 xsm927

    #动脉炎#

    0

  3. 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    2013-10-08 1249898am15暂无昵称

    #带状疱疹病毒#

    0

  4. 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encryptionId=e3eb89e17fb, topicName=血管病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=64bb23195917, createdName=Luyuxie_17, createdTime=Mon Sep 23 15:26:00 CST 2013, time=2013-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2023852, encodeId=dbe320238520b, content=<a href='/topic/show?id=99c864229d5' target=_blank style='color:#2F92EE;'>#水痘带状疱疹病毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64229, encryptionId=99c864229d5, topicName=水痘带状疱疹病毒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccbd84, createdName=shizhenshan, createdTime=Wed May 14 19:26:00 CST 2014, time=2014-05-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1986332, encodeId=ad3a198633266, content=<a href='/topic/show?id=f3f1e0930ed' target=_blank style='color:#2F92EE;'>#病毒性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70930, encryptionId=f3f1e0930ed, topicName=病毒性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Sat Feb 22 21:26:00 CST 2014, time=2014-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1999304, encodeId=725c199930474, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Wed Mar 19 21:26:00 CST 2014, time=2014-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1478584, encodeId=855614e8584e6, content=<a href='/topic/show?id=73d26422888' target=_blank style='color:#2F92EE;'>#水痘#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64228, encryptionId=73d26422888, topicName=水痘)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7d957440250, createdName=1249857fm34暂无昵称, createdTime=Sat Jun 08 01:26:00 CST 2013, time=2013-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1580335, encodeId=8a1c158033548, content=<a href='/topic/show?id=c026e05485f' target=_blank style='color:#2F92EE;'>#疱疹#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70548, encryptionId=c026e05485f, topicName=疱疹)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2dcf16628144, createdName=ms2694732865965676, createdTime=Sat Jun 08 01:26:00 CST 2013, time=2013-06-08, status=1, ipAttribution=)]
    2013-09-23 Luyuxie_17

    #血管病#

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1820334, encodeId=71a8182033464, content=<a href='/topic/show?id=f916100e7446' target=_blank style='color:#2F92EE;'>#颞动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100774, encryptionId=f916100e7446, topicName=颞动脉)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Wed Oct 23 01:26:00 CST 2013, time=2013-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1683156, encodeId=3679168315611, content=<a href='/topic/show?id=60f03325e28' target=_blank style='color:#2F92EE;'>#动脉炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33257, encryptionId=60f03325e28, topicName=动脉炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d22a27947071, createdName=xsm927, createdTime=Sun Aug 18 10:26:00 CST 2013, time=2013-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2054581, encodeId=a5772054581b0, content=<a href='/topic/show?id=30ae48556fd' target=_blank style='color:#2F92EE;'>#带状疱疹病毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48556, encryptionId=30ae48556fd, topicName=带状疱疹病毒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=38232500109, createdName=1249898am15暂无昵称, createdTime=Tue Oct 08 09:26:00 CST 2013, time=2013-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1644373, encodeId=db4016443e300, content=<a href='/topic/show?id=e3eb89e17fb' target=_blank style='color:#2F92EE;'>#血管病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89717, encryptionId=e3eb89e17fb, topicName=血管病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=64bb23195917, createdName=Luyuxie_17, createdTime=Mon Sep 23 15:26:00 CST 2013, time=2013-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2023852, encodeId=dbe320238520b, content=<a href='/topic/show?id=99c864229d5' target=_blank style='color:#2F92EE;'>#水痘带状疱疹病毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64229, encryptionId=99c864229d5, topicName=水痘带状疱疹病毒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccbd84, createdName=shizhenshan, createdTime=Wed May 14 19:26:00 CST 2014, time=2014-05-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1986332, encodeId=ad3a198633266, content=<a href='/topic/show?id=f3f1e0930ed' target=_blank style='color:#2F92EE;'>#病毒性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70930, encryptionId=f3f1e0930ed, topicName=病毒性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Sat Feb 22 21:26:00 CST 2014, time=2014-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1999304, encodeId=725c199930474, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Wed Mar 19 21:26:00 CST 2014, time=2014-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1478584, encodeId=855614e8584e6, content=<a href='/topic/show?id=73d26422888' target=_blank style='color:#2F92EE;'>#水痘#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64228, encryptionId=73d26422888, topicName=水痘)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7d957440250, createdName=1249857fm34暂无昵称, createdTime=Sat Jun 08 01:26:00 CST 2013, time=2013-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1580335, encodeId=8a1c158033548, content=<a href='/topic/show?id=c026e05485f' target=_blank style='color:#2F92EE;'>#疱疹#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70548, encryptionId=c026e05485f, topicName=疱疹)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2dcf16628144, createdName=ms2694732865965676, createdTime=Sat Jun 08 01:26:00 CST 2013, time=2013-06-08, status=1, ipAttribution=)]
    2014-05-14 shizhenshan

    #水痘带状疱疹病毒#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1820334, encodeId=71a8182033464, content=<a href='/topic/show?id=f916100e7446' target=_blank style='color:#2F92EE;'>#颞动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100774, encryptionId=f916100e7446, topicName=颞动脉)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Wed Oct 23 01:26:00 CST 2013, time=2013-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1683156, encodeId=3679168315611, content=<a href='/topic/show?id=60f03325e28' target=_blank style='color:#2F92EE;'>#动脉炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33257, encryptionId=60f03325e28, topicName=动脉炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d22a27947071, 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encryptionId=e3eb89e17fb, topicName=血管病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=64bb23195917, createdName=Luyuxie_17, createdTime=Mon Sep 23 15:26:00 CST 2013, time=2013-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2023852, encodeId=dbe320238520b, content=<a href='/topic/show?id=99c864229d5' target=_blank style='color:#2F92EE;'>#水痘带状疱疹病毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64229, encryptionId=99c864229d5, topicName=水痘带状疱疹病毒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccbd84, createdName=shizhenshan, createdTime=Wed May 14 19:26:00 CST 2014, time=2014-05-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1986332, encodeId=ad3a198633266, content=<a href='/topic/show?id=f3f1e0930ed' target=_blank style='color:#2F92EE;'>#病毒性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70930, encryptionId=f3f1e0930ed, topicName=病毒性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Sat Feb 22 21:26:00 CST 2014, time=2014-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1999304, encodeId=725c199930474, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Wed Mar 19 21:26:00 CST 2014, time=2014-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1478584, encodeId=855614e8584e6, content=<a href='/topic/show?id=73d26422888' target=_blank style='color:#2F92EE;'>#水痘#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64228, encryptionId=73d26422888, topicName=水痘)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7d957440250, createdName=1249857fm34暂无昵称, createdTime=Sat Jun 08 01:26:00 CST 2013, time=2013-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1580335, encodeId=8a1c158033548, content=<a href='/topic/show?id=c026e05485f' target=_blank style='color:#2F92EE;'>#疱疹#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70548, encryptionId=c026e05485f, topicName=疱疹)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2dcf16628144, createdName=ms2694732865965676, createdTime=Sat Jun 08 01:26:00 CST 2013, time=2013-06-08, status=1, ipAttribution=)]
    2014-02-22 howi

    #病毒性#

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1820334, encodeId=71a8182033464, content=<a href='/topic/show?id=f916100e7446' target=_blank style='color:#2F92EE;'>#颞动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100774, encryptionId=f916100e7446, topicName=颞动脉)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Wed Oct 23 01:26:00 CST 2013, time=2013-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1683156, encodeId=3679168315611, content=<a href='/topic/show?id=60f03325e28' target=_blank style='color:#2F92EE;'>#动脉炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33257, encryptionId=60f03325e28, topicName=动脉炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d22a27947071, createdName=xsm927, createdTime=Sun Aug 18 10:26:00 CST 2013, time=2013-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2054581, encodeId=a5772054581b0, content=<a href='/topic/show?id=30ae48556fd' target=_blank style='color:#2F92EE;'>#带状疱疹病毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48556, encryptionId=30ae48556fd, topicName=带状疱疹病毒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=38232500109, createdName=1249898am15暂无昵称, createdTime=Tue Oct 08 09:26:00 CST 2013, time=2013-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1644373, encodeId=db4016443e300, content=<a href='/topic/show?id=e3eb89e17fb' target=_blank style='color:#2F92EE;'>#血管病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89717, encryptionId=e3eb89e17fb, topicName=血管病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=64bb23195917, createdName=Luyuxie_17, createdTime=Mon Sep 23 15:26:00 CST 2013, time=2013-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2023852, encodeId=dbe320238520b, content=<a href='/topic/show?id=99c864229d5' target=_blank style='color:#2F92EE;'>#水痘带状疱疹病毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64229, encryptionId=99c864229d5, topicName=水痘带状疱疹病毒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccbd84, createdName=shizhenshan, createdTime=Wed May 14 19:26:00 CST 2014, time=2014-05-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1986332, encodeId=ad3a198633266, content=<a href='/topic/show?id=f3f1e0930ed' target=_blank style='color:#2F92EE;'>#病毒性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70930, encryptionId=f3f1e0930ed, topicName=病毒性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Sat Feb 22 21:26:00 CST 2014, time=2014-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1999304, encodeId=725c199930474, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Wed Mar 19 21:26:00 CST 2014, time=2014-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1478584, encodeId=855614e8584e6, content=<a href='/topic/show?id=73d26422888' target=_blank style='color:#2F92EE;'>#水痘#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64228, encryptionId=73d26422888, topicName=水痘)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7d957440250, createdName=1249857fm34暂无昵称, createdTime=Sat Jun 08 01:26:00 CST 2013, time=2013-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1580335, encodeId=8a1c158033548, content=<a href='/topic/show?id=c026e05485f' target=_blank style='color:#2F92EE;'>#疱疹#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70548, encryptionId=c026e05485f, topicName=疱疹)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2dcf16628144, createdName=ms2694732865965676, createdTime=Sat Jun 08 01:26:00 CST 2013, time=2013-06-08, status=1, ipAttribution=)]
    2014-03-19 yinhl1978

    #Neurol#

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1820334, encodeId=71a8182033464, content=<a href='/topic/show?id=f916100e7446' target=_blank style='color:#2F92EE;'>#颞动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100774, encryptionId=f916100e7446, topicName=颞动脉)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Wed Oct 23 01:26:00 CST 2013, time=2013-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1683156, encodeId=3679168315611, content=<a href='/topic/show?id=60f03325e28' target=_blank style='color:#2F92EE;'>#动脉炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33257, encryptionId=60f03325e28, topicName=动脉炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d22a27947071, createdName=xsm927, createdTime=Sun Aug 18 10:26:00 CST 2013, time=2013-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2054581, encodeId=a5772054581b0, content=<a href='/topic/show?id=30ae48556fd' target=_blank style='color:#2F92EE;'>#带状疱疹病毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48556, encryptionId=30ae48556fd, topicName=带状疱疹病毒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=38232500109, createdName=1249898am15暂无昵称, createdTime=Tue Oct 08 09:26:00 CST 2013, time=2013-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1644373, encodeId=db4016443e300, content=<a href='/topic/show?id=e3eb89e17fb' target=_blank style='color:#2F92EE;'>#血管病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89717, encryptionId=e3eb89e17fb, topicName=血管病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=64bb23195917, createdName=Luyuxie_17, createdTime=Mon Sep 23 15:26:00 CST 2013, time=2013-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2023852, encodeId=dbe320238520b, content=<a href='/topic/show?id=99c864229d5' target=_blank style='color:#2F92EE;'>#水痘带状疱疹病毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64229, encryptionId=99c864229d5, topicName=水痘带状疱疹病毒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccbd84, createdName=shizhenshan, createdTime=Wed May 14 19:26:00 CST 2014, time=2014-05-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1986332, encodeId=ad3a198633266, content=<a href='/topic/show?id=f3f1e0930ed' target=_blank style='color:#2F92EE;'>#病毒性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70930, encryptionId=f3f1e0930ed, topicName=病毒性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Sat Feb 22 21:26:00 CST 2014, time=2014-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1999304, encodeId=725c199930474, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Wed Mar 19 21:26:00 CST 2014, time=2014-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1478584, encodeId=855614e8584e6, content=<a href='/topic/show?id=73d26422888' target=_blank style='color:#2F92EE;'>#水痘#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64228, encryptionId=73d26422888, topicName=水痘)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7d957440250, createdName=1249857fm34暂无昵称, createdTime=Sat Jun 08 01:26:00 CST 2013, time=2013-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1580335, encodeId=8a1c158033548, content=<a href='/topic/show?id=c026e05485f' target=_blank style='color:#2F92EE;'>#疱疹#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70548, encryptionId=c026e05485f, topicName=疱疹)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2dcf16628144, createdName=ms2694732865965676, createdTime=Sat Jun 08 01:26:00 CST 2013, time=2013-06-08, status=1, ipAttribution=)]
    2013-06-08 1249857fm34暂无昵称

    #水痘#

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1820334, encodeId=71a8182033464, content=<a href='/topic/show?id=f916100e7446' target=_blank style='color:#2F92EE;'>#颞动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100774, encryptionId=f916100e7446, topicName=颞动脉)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Wed Oct 23 01:26:00 CST 2013, time=2013-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1683156, encodeId=3679168315611, content=<a href='/topic/show?id=60f03325e28' target=_blank style='color:#2F92EE;'>#动脉炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33257, encryptionId=60f03325e28, topicName=动脉炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d22a27947071, createdName=xsm927, createdTime=Sun Aug 18 10:26:00 CST 2013, time=2013-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2054581, encodeId=a5772054581b0, content=<a href='/topic/show?id=30ae48556fd' target=_blank style='color:#2F92EE;'>#带状疱疹病毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48556, encryptionId=30ae48556fd, topicName=带状疱疹病毒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=38232500109, createdName=1249898am15暂无昵称, createdTime=Tue Oct 08 09:26:00 CST 2013, time=2013-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1644373, encodeId=db4016443e300, content=<a href='/topic/show?id=e3eb89e17fb' target=_blank style='color:#2F92EE;'>#血管病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89717, encryptionId=e3eb89e17fb, topicName=血管病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=64bb23195917, createdName=Luyuxie_17, createdTime=Mon Sep 23 15:26:00 CST 2013, time=2013-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2023852, encodeId=dbe320238520b, content=<a href='/topic/show?id=99c864229d5' target=_blank style='color:#2F92EE;'>#水痘带状疱疹病毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64229, encryptionId=99c864229d5, topicName=水痘带状疱疹病毒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccbd84, createdName=shizhenshan, createdTime=Wed May 14 19:26:00 CST 2014, time=2014-05-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1986332, encodeId=ad3a198633266, content=<a href='/topic/show?id=f3f1e0930ed' target=_blank style='color:#2F92EE;'>#病毒性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70930, encryptionId=f3f1e0930ed, topicName=病毒性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Sat Feb 22 21:26:00 CST 2014, time=2014-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1999304, encodeId=725c199930474, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Wed Mar 19 21:26:00 CST 2014, time=2014-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1478584, encodeId=855614e8584e6, content=<a href='/topic/show?id=73d26422888' target=_blank style='color:#2F92EE;'>#水痘#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64228, encryptionId=73d26422888, topicName=水痘)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7d957440250, createdName=1249857fm34暂无昵称, createdTime=Sat Jun 08 01:26:00 CST 2013, time=2013-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1580335, encodeId=8a1c158033548, content=<a href='/topic/show?id=c026e05485f' target=_blank style='color:#2F92EE;'>#疱疹#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70548, encryptionId=c026e05485f, topicName=疱疹)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2dcf16628144, createdName=ms2694732865965676, createdTime=Sat Jun 08 01:26:00 CST 2013, time=2013-06-08, status=1, ipAttribution=)]
    2013-06-08 ms2694732865965676

    #疱疹#

    0