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Neurology：卒中后降压治疗依从性高低决定心血管事件风险

2012-11-26 MedSci Neurology

Neurology卒中降压
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降压药依从性好的患者非致死性心血管事件发生率降低 高血压是全因卒中的可干预危险因素。其发病率在逐渐增加。加拿大Montreal大学药学系的Sylvie Perreault博士等人通过研究发现：对降压治疗依从性高的患者，卒中后非致死性心血管事件的发生率降低。相关论文发表在Neurology杂志2012年10月31日在线版上。 研究人员进行队列研究，纳入1999至2007年加拿大魁北克的1422


降压药依从性好的患者非致死性心血管事件发生率降低

高血压是全因卒中的可干预危险因素。其发病率在逐渐增加。加拿大Montreal大学药学系的Sylvie Perreault博士等人通过研究发现：对降压治疗依从性高的患者，卒中后非致死性心血管事件的发生率降低。相关论文发表在Neurology杂志2012年10月31日在线版上。

研究人员进行队列研究，纳入1999至2007年加拿大魁北克的14227位诊断为缺血性卒中的患者，他们年龄在65岁以上，进行降压药物治疗。设计嵌套病例对照试验评估非致死性主要心血管事件的发生率和死亡事件的发生率。根据年龄和进入队列时间为每个病例匹配15个对照。药物使用率用来评估心血管事件的比值比。方法的有效性通过评价心血管事件保护药物和非保护药物的依从水平。

结果发现：平均年龄75岁，54%为男性，38%有冠心病，23%有糖尿病，47%有血脂异常，14%有心房颤动或房扑。降压药物治疗的高依从性伴随他汀和抗血小板药物的高依从性，相较低依从性患者，非致死性血管事件风险降低(比值比 0.77 [0.70–0.86])。很多药物存在着使用依从性越高，全因死亡率越低。

研究人员得出结论：对降压药物的依从性高往往对其它二级预防治疗的依从性也高，从而降低缺血性卒中后非致死性血管事件的风险。全因死亡率降低程度的高估可能与患者的身体脆弱及并发症相关，这可能混淆不同药物的明显获益。 

原始链接：

Perreault S, Yu AY, Côté R, Dragomir A, White-Guay B, Dumas S.Adherence to antihypertensive agents after ischemic stroke and risk of cardiovascular outcomes.Neurology. 2012 Nov 13;79(20):2037-43. doi: 10.1212/WNL.0b013e3182749e56. Epub 2012 Oct 31.

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    2013-07-16 yinhl1978

    #Neurol#

    0

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    2013-02-19 zsyan

    #治疗依从性#

    0

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    2013-07-15 hukaixun

    #血管事件#

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1999232, encodeId=2c441999232c3, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Tue Jul 16 22:08:00 CST 2013, time=2013-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1951679, encodeId=f83219516e981, content=<a href='/topic/show?id=dcfc6458314' target=_blank style='color:#2F92EE;'>#治疗依从性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64583, encryptionId=dcfc6458314, topicName=治疗依从性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dab8203, createdName=zsyan, createdTime=Tue Feb 19 15:08:00 CST 2013, time=2013-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1643298, encodeId=cbbe1643298cb, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Mon Jul 15 09:08:00 CST 2013, time=2013-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1671163, encodeId=01bb16e1163c5, content=<a href='/topic/show?id=9f4e360191a' target=_blank style='color:#2F92EE;'>#卒中后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36019, encryptionId=9f4e360191a, topicName=卒中后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ff7426824786, createdName=waiwai3039, createdTime=Mon Jan 14 05:08:00 CST 2013, time=2013-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1287597, encodeId=e55a128e597c6, content=<a href='/topic/show?id=3c3d51e4459' target=_blank style='color:#2F92EE;'>#心血管事件风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51744, encryptionId=3c3d51e4459, topicName=心血管事件风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Wed Nov 28 06:08:00 CST 2012, time=2012-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1291782, encodeId=616a1291e8278, content=<a href='/topic/show?id=9d32981418b' target=_blank style='color:#2F92EE;'>#降压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98141, encryptionId=9d32981418b, topicName=降压)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f14236, createdName=经常头晕, createdTime=Wed Nov 28 06:08:00 CST 2012, time=2012-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1319232, encodeId=d17c131923248, content=<a href='/topic/show?id=60172686668' target=_blank style='color:#2F92EE;'>#依从性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26866, encryptionId=60172686668, topicName=依从性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9df476, createdName=fyxzlh, createdTime=Wed Nov 28 06:08:00 CST 2012, time=2012-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1360827, encodeId=5ec4136082eca, content=<a href='/topic/show?id=87fe98146d7' target=_blank style='color:#2F92EE;'>#降压治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98146, encryptionId=87fe98146d7, topicName=降压治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=xugumin, createdTime=Wed Nov 28 06:08:00 CST 2012, time=2012-11-28, status=1, ipAttribution=)]
    2013-01-14 waiwai3039

    #卒中后#

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1999232, encodeId=2c441999232c3, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Tue Jul 16 22:08:00 CST 2013, time=2013-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1951679, encodeId=f83219516e981, content=<a href='/topic/show?id=dcfc6458314' target=_blank style='color:#2F92EE;'>#治疗依从性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64583, encryptionId=dcfc6458314, topicName=治疗依从性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dab8203, createdName=zsyan, createdTime=Tue Feb 19 15:08:00 CST 2013, time=2013-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1643298, encodeId=cbbe1643298cb, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Mon Jul 15 09:08:00 CST 2013, time=2013-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1671163, encodeId=01bb16e1163c5, content=<a href='/topic/show?id=9f4e360191a' target=_blank style='color:#2F92EE;'>#卒中后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36019, encryptionId=9f4e360191a, topicName=卒中后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ff7426824786, createdName=waiwai3039, createdTime=Mon Jan 14 05:08:00 CST 2013, time=2013-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1287597, encodeId=e55a128e597c6, content=<a href='/topic/show?id=3c3d51e4459' target=_blank style='color:#2F92EE;'>#心血管事件风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51744, encryptionId=3c3d51e4459, topicName=心血管事件风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Wed Nov 28 06:08:00 CST 2012, time=2012-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1291782, encodeId=616a1291e8278, content=<a href='/topic/show?id=9d32981418b' target=_blank style='color:#2F92EE;'>#降压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98141, encryptionId=9d32981418b, topicName=降压)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f14236, createdName=经常头晕, createdTime=Wed Nov 28 06:08:00 CST 2012, time=2012-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1319232, encodeId=d17c131923248, content=<a href='/topic/show?id=60172686668' target=_blank style='color:#2F92EE;'>#依从性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26866, encryptionId=60172686668, topicName=依从性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9df476, createdName=fyxzlh, createdTime=Wed Nov 28 06:08:00 CST 2012, time=2012-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1360827, encodeId=5ec4136082eca, content=<a href='/topic/show?id=87fe98146d7' target=_blank style='color:#2F92EE;'>#降压治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98146, encryptionId=87fe98146d7, topicName=降压治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=xugumin, createdTime=Wed Nov 28 06:08:00 CST 2012, time=2012-11-28, status=1, ipAttribution=)]
    2012-11-28 zhanfl

    #心血管事件风险#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1999232, encodeId=2c441999232c3, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Tue Jul 16 22:08:00 CST 2013, time=2013-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1951679, encodeId=f83219516e981, content=<a href='/topic/show?id=dcfc6458314' target=_blank style='color:#2F92EE;'>#治疗依从性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64583, encryptionId=dcfc6458314, topicName=治疗依从性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dab8203, createdName=zsyan, createdTime=Tue Feb 19 15:08:00 CST 2013, time=2013-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1643298, encodeId=cbbe1643298cb, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Mon Jul 15 09:08:00 CST 2013, time=2013-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1671163, encodeId=01bb16e1163c5, content=<a href='/topic/show?id=9f4e360191a' target=_blank style='color:#2F92EE;'>#卒中后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36019, encryptionId=9f4e360191a, topicName=卒中后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ff7426824786, createdName=waiwai3039, createdTime=Mon Jan 14 05:08:00 CST 2013, time=2013-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1287597, encodeId=e55a128e597c6, content=<a href='/topic/show?id=3c3d51e4459' target=_blank style='color:#2F92EE;'>#心血管事件风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51744, encryptionId=3c3d51e4459, topicName=心血管事件风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Wed Nov 28 06:08:00 CST 2012, time=2012-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1291782, encodeId=616a1291e8278, content=<a href='/topic/show?id=9d32981418b' target=_blank style='color:#2F92EE;'>#降压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98141, encryptionId=9d32981418b, topicName=降压)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f14236, createdName=经常头晕, createdTime=Wed Nov 28 06:08:00 CST 2012, time=2012-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1319232, encodeId=d17c131923248, content=<a href='/topic/show?id=60172686668' target=_blank style='color:#2F92EE;'>#依从性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26866, encryptionId=60172686668, topicName=依从性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9df476, createdName=fyxzlh, createdTime=Wed Nov 28 06:08:00 CST 2012, time=2012-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1360827, encodeId=5ec4136082eca, content=<a href='/topic/show?id=87fe98146d7' target=_blank style='color:#2F92EE;'>#降压治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98146, encryptionId=87fe98146d7, topicName=降压治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=xugumin, createdTime=Wed Nov 28 06:08:00 CST 2012, time=2012-11-28, status=1, ipAttribution=)]
    2012-11-28 经常头晕

    #降压#

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1999232, encodeId=2c441999232c3, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Tue Jul 16 22:08:00 CST 2013, time=2013-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1951679, encodeId=f83219516e981, content=<a href='/topic/show?id=dcfc6458314' target=_blank style='color:#2F92EE;'>#治疗依从性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64583, encryptionId=dcfc6458314, topicName=治疗依从性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dab8203, createdName=zsyan, createdTime=Tue Feb 19 15:08:00 CST 2013, time=2013-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1643298, encodeId=cbbe1643298cb, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Mon Jul 15 09:08:00 CST 2013, time=2013-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1671163, encodeId=01bb16e1163c5, content=<a href='/topic/show?id=9f4e360191a' target=_blank style='color:#2F92EE;'>#卒中后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36019, encryptionId=9f4e360191a, topicName=卒中后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ff7426824786, createdName=waiwai3039, createdTime=Mon Jan 14 05:08:00 CST 2013, time=2013-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1287597, encodeId=e55a128e597c6, content=<a href='/topic/show?id=3c3d51e4459' target=_blank style='color:#2F92EE;'>#心血管事件风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51744, encryptionId=3c3d51e4459, topicName=心血管事件风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Wed Nov 28 06:08:00 CST 2012, time=2012-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1291782, encodeId=616a1291e8278, content=<a href='/topic/show?id=9d32981418b' target=_blank style='color:#2F92EE;'>#降压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98141, encryptionId=9d32981418b, topicName=降压)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f14236, createdName=经常头晕, createdTime=Wed Nov 28 06:08:00 CST 2012, time=2012-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1319232, encodeId=d17c131923248, content=<a href='/topic/show?id=60172686668' target=_blank style='color:#2F92EE;'>#依从性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26866, encryptionId=60172686668, topicName=依从性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9df476, createdName=fyxzlh, createdTime=Wed Nov 28 06:08:00 CST 2012, time=2012-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1360827, encodeId=5ec4136082eca, content=<a href='/topic/show?id=87fe98146d7' target=_blank style='color:#2F92EE;'>#降压治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98146, encryptionId=87fe98146d7, topicName=降压治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=xugumin, createdTime=Wed Nov 28 06:08:00 CST 2012, time=2012-11-28, status=1, ipAttribution=)]
    2012-11-28 fyxzlh

    #依从性#

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1999232, encodeId=2c441999232c3, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Tue Jul 16 22:08:00 CST 2013, time=2013-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1951679, encodeId=f83219516e981, content=<a href='/topic/show?id=dcfc6458314' target=_blank style='color:#2F92EE;'>#治疗依从性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64583, encryptionId=dcfc6458314, topicName=治疗依从性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dab8203, createdName=zsyan, createdTime=Tue Feb 19 15:08:00 CST 2013, time=2013-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1643298, encodeId=cbbe1643298cb, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Mon Jul 15 09:08:00 CST 2013, time=2013-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1671163, encodeId=01bb16e1163c5, content=<a href='/topic/show?id=9f4e360191a' target=_blank style='color:#2F92EE;'>#卒中后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36019, encryptionId=9f4e360191a, topicName=卒中后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ff7426824786, createdName=waiwai3039, createdTime=Mon Jan 14 05:08:00 CST 2013, time=2013-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1287597, encodeId=e55a128e597c6, content=<a href='/topic/show?id=3c3d51e4459' target=_blank style='color:#2F92EE;'>#心血管事件风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51744, encryptionId=3c3d51e4459, topicName=心血管事件风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Wed Nov 28 06:08:00 CST 2012, time=2012-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1291782, encodeId=616a1291e8278, content=<a href='/topic/show?id=9d32981418b' target=_blank style='color:#2F92EE;'>#降压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98141, encryptionId=9d32981418b, topicName=降压)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f14236, createdName=经常头晕, createdTime=Wed Nov 28 06:08:00 CST 2012, time=2012-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1319232, encodeId=d17c131923248, content=<a href='/topic/show?id=60172686668' target=_blank style='color:#2F92EE;'>#依从性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26866, encryptionId=60172686668, topicName=依从性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9df476, createdName=fyxzlh, createdTime=Wed Nov 28 06:08:00 CST 2012, time=2012-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1360827, encodeId=5ec4136082eca, content=<a href='/topic/show?id=87fe98146d7' target=_blank style='color:#2F92EE;'>#降压治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98146, encryptionId=87fe98146d7, topicName=降压治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=xugumin, createdTime=Wed Nov 28 06:08:00 CST 2012, time=2012-11-28, status=1, ipAttribution=)]
    2012-11-28 xugumin

    #降压治疗#

    0