J Infect Dis: 通过呼气分析诊断人类棘球蚴病

2018-12-19 MedSci MedSci原创

人类棘球蚴病是一种被忽视的传染病,但它在全球影响着超过100万人。由于在这种病大都发生在资源贫乏地区,诊断费用昂贵且十分困难,因此如何快速有效诊断这种病是当务之急,本项研究旨在发明一种新型的诊断方法提高此病的诊断效率。

背景及目的
人类棘球蚴病是一种被忽视的传染病,但它在全球影响着超过100万人。由于在这种病大都发生在资源贫乏地区,诊断费用昂贵且十分困难,因此如何快速有效诊断这种病是当务之急,本项研究旨在发明一种新型的诊断方法提高此病的诊断效率。

方法
研究人员从突尼斯医院召集了32名囊性棘球蚴病患者和43名对照组患者以及波兰16名肺泡包虫病患者和8名对照组患者,研究人员从所有患者中收集呼吸样品,并通过气相色谱与质谱联用分析,以及专门开发的电子系统进行气体相关分析。

结果
化学分析显示,与对照组相比,囊性棘球蚴病患者呼吸中2种化合物的浓度存在统计学差异,与对照组相比,肺泡棘球蚴病患者呼吸中7种化合物的统计学差异有统计学差异。电子鼻系统对囊性棘球蚴病的鉴别准确率为100%,肺泡包虫病的鉴别准确率为92.9%,而这两个患者组之间的鉴别准确率为92.1%。

结论
本项研究为贫困地区患人类棘球蚴病患者提供了一种无创,快速,易操作且廉价的诊断工具,通过呼气分析诊断人类棘球蚴病,适合早期诊断和人群筛查

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    2018-12-20 飛歌

    学习了很有用不错

    0

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    2018-12-20 深海的鱼

    学习学习学习

    0

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    2018-12-19 清风拂面

    谢谢分享学习

    0