表观遗传学研究进入春天,谷歌风投2100万美元

2016-03-26 佚名 生物谷

  Cambridge Epigenetix在B轮融资中拿到2100万美元资金,其中大部分来源于谷歌风投。公司已经宣布对公司高层进行人事调整。 Cambridge Epigenetix的缩写为CEGX,致力于开发表观遗传学测序技术,是2012年从剑桥大学独立出去的生命科学公司。 这轮融资是谷歌风投(GV)主导的,其他参与的公司包括Sequoia Capital(现在称新科学风投)

 

Cambridge Epigenetix在B轮融资中拿到2100万美元资金,其中大部分来源于谷歌风投。公司已经宣布对公司高层进行人事调整。

Cambridge Epigenetix的缩写为CEGX,致力于开发表观遗传学测序技术,是2012年从剑桥大学独立出去的生命科学公司。

这轮融资是谷歌风投(GV)主导的,其他参与的公司包括Sequoia Capital(现在称新科学风投),Wellcome Trust的 Syncona Partners 和剑桥大学。

作为GV的主要合作伙伴,Tom Hulme将进入董事会,Bobby Yerramilli-Rao将就任董事会主席。

该公司任命了Geoff Smith作为新的CEO。Smith之前在加利福尼亚的Illumina公司工作,主管产品开发;进入新公司之后,主管工作和原公司基本相同。

2014年,CEGX公司的启动注册资金为5500万美元,由前首席执行官Fedja Bobanovic掌舵。目前Fedja Bobanovic已经离开CEGX,就任莱卡公司的副总董长。

癌症、自发免疫性疾病和神经性病变都可能由异常的表观遗传学变化引起,有望通过“关闭”相应的异常基因得到治疗。事实上,目前已经有一些公司开始这方面的研究,比如Celgene公司就是其中的佼佼者,目前已经开发出血液肿瘤药物Vidaza和T细胞淋巴瘤药物Istodax。

花旗集团最近的报告中估计:2025年,表观遗传学在癌症治疗领域的市场份额大约为100亿美元,CEGX将会占领一大部分。

该风投的共同创始人Shankar Balasubramanian也希望能够在CEGX身上复制Solexa(现在被Illumina收购)的成功。Solexa是1998年创立的,也是从大学分离出来的公司。Shankar Balasubramanian成功实现了Solexa公司的快速DNA测序方法的商业化。

Smith在声明中提到:“CEGX今天已经成功地进入到将表观遗传学商业化的境地——就像10多年以前推进Soxexa和Illumina公司测序一样——我对能够在这样一个时刻——一个历史性转折的关键时候,同时也是推出新一代表观遗传学产品的时候——加入,感到非常荣幸。”

Yerramilli-Rao说:“CEGX的使命是通过持续地测定表观基因组,推进民众健康。CEGX的最新技术允许科学家揭开表观基因组蕴藏的无穷奥秘。”

CEGX目前致力于从遗传密码的4个数字中寻找特异性的标签。最重要的3个标签为甲基化、羟乙基化和甲酰化。目前业界普遍认为:在不同的环境中,这些标签可以改变(开启或者关闭)基因表达。

Hulme说:“我们已经看到了基因组测序商业化,在提高民众健康方面的无穷潜能;而当今的表观遗传学也有这个潜力。Cambridge Epigenetix是该领域为数不多具有专门技术和经验的公司,具有开疆辟土的能力,我们期待着与公司共同完成这个壮举,并给予资金上的支持。”

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    2016-08-27 李东泽

    这篇资讯带给我们新知识,启发新思维,不论是科研还是临床工作都有很大的帮助。。。

    0

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    2016-08-27 李东泽

    这篇资讯带给我们新知识,启发新思维,不论是科研还是临床工作都有很大的帮助。。。

    0

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    2016-03-28 wei834766788

    不清楚相关领域

    0

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    2016-03-28 wei834766788

    不太懂

    0

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    2016-03-28 Gsurgeon

    什么是表观遗传学

    0

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    2016-03-28 isabellayj

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