J Oral Sci:咀嚼口香糖可缓解灼口综合征患者的疼痛程度

2021-08-21 MedSci原创 MedSci原创

灼口综合征(BMS)的原因尚不清楚。虽然没有建立有效的治疗方法,但BMS患者经常咀嚼口香糖以减轻疼痛。为了确定BMS的原因和新的治疗方法,研究人员调查了咀嚼口香糖的心理物理学和药理学特性,以更好地了解

灼口综合征(BMS)的原因尚不清楚。虽然没有建立有效的治疗方法,但BMS患者经常咀嚼口香糖以减轻疼痛。为了确定BMS的原因和新的治疗方法,研究人员调查了咀嚼口香糖的心理物理学和药理学特性,以更好地了解其缓解疼痛的作用。

这项前瞻性的盲法研究共纳入40名女性,1:1随机分组,BMS组和对照组,在咀嚼口香糖或模拟咀嚼后评估了血浆儿茶酚胺和血清素水平以及情绪状态档案(POMS)得分。

 

结果显示,BMS患者在咀嚼口香糖和模拟咀嚼后,疼痛的视觉模拟量表(VAS)评分明显下降。BMS患者的静止VAS评分与血浆肾上腺素水平呈显著正相关。此外,咀嚼口香糖与较低的血浆肾上腺素水平、VAS评分和紧张-焦虑评分明显相关。

综上,这些结果表明,肾上腺素在BMS疼痛的发病机制中很重要,咀嚼口香糖的镇痛作用是通过减少焦虑的潜在作用而诱发的,而非针对BMS。此外,咀嚼口香糖的镇痛作用并非仅仅由咀嚼动作诱发。

 

原始出处:

 

Naohiko Sekine, et al., Analgesic effect of gum chewing in patients with burning mouth syndrome. J Oral Sci. 2020 Sep 26;62(4):387-392. doi: 10.2334/josnusd.19-0501.

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    2022-07-06 ms8000001255329993

    让BMS患者试试

    0

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    2022-01-20 Boyinsh
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    2022-06-28 小几洁
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    2021-08-22 ms7000001545202350

    学习了

    0

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    2021-08-22 1977刘刘

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