Ophthalmic Res:中枢性糖尿病性黄斑病变患者中双眼定视降低较差眼睛的固定眼动

2017-07-08 cuiguizhong MedSci原创

丹麦奥胡斯奥胡斯大学医院眼科系的Jakobsen NS近日在Ophthalmic Res发表了他们最近的一项工作,他们比较了糖尿病性黄斑病变患者在单眼定视和双眼定视时眼动的差别,发现双眼定视降低较差眼睛的固定眼动。

丹麦奥胡斯奥胡斯大学医院眼科系的Jakobsen NS近日在Ophthalmic Res发表了他们最近的一项工作,他们比较了糖尿病性黄斑病变患者在单眼定视和双眼定视时眼动的差别,发现双眼定视降低较差眼睛的固定眼动。

血管内皮生长因子抑制剂治疗糖尿病性黄斑病变在一些患者中无效,因此,应检测治疗后视力的相关参数。已有的研究表明,在糖尿病性黄斑病变继发性视力降低的患者中,定位扫视增加。但是在双眼定视期间,由糖尿病性黄斑病变影响的眼睛中,一个眼睛运动受到另一只眼睛的影响尚不清楚。

作者研究了57例患者,其中29例是明显的临床黄斑水肿的糖尿病患者。他们使用iView X?眼动仪记录了定视时眼动作,定量测量了定视期间较差眼睛的参数,并比较了单目和双目定视的差别。

他们发现,在单眼定视期间的固定扫视具有显着较高的眼动频率(p = 0.005),较大的幅度(p = 0.03),并且比双眼定视期间有更大的视网膜面积(p = 0.02)。有趣的发现是,在单眼定视期间,视力与定视的面积之间存在显着的负相关性(r2 = 0.18,p = 0.02),而在双眼定视期间没有这种现象(r2 = 0.007,p = 0.68)。

因此,他们认为,双眼定视可以减少糖尿病性黄斑病患者眼中较差眼睛的定视面积和定视扫视的幅度。在单眼定视期间,糖尿病性黄斑病变的固定扫视还需要进一步的研究。

原文出处:

Jakobsen N S, Larsen D A, Bek T. Binocular fixation reduces fixational eye movements in the most affected eye of patients with center involving diabetic macular oedema[J]. Investigative Ophthalmology & Visual Science, 2017, 58(8): 750-750.

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