Am Heart J:耐力训练无益于射血分数正常心衰患者

2012-11-07 Am Heart J Am Heart J

  美国学者的一项研究表明,为期1年的耐力训练未能改善射血分数正常心衰(HFPEF)患者的心血管僵硬度和功能。论文于2012年10月31日在线发表于《美国心脏杂志》(Am Heart J)。   此项研究共纳入11例HFPEF患者和13例健康对照者。采用有创右心导管测定Starling和左室压力-容积曲线;次要功能转归包括超声心动图、动脉硬度、心肺运动试验和心室-动脉偶联。7

  美国学者的一项研究表明,为期1年的耐力训练未能改善射血分数正常心衰(HFPEF)患者的心血管僵硬度和功能。论文于2012年10月31日在线发表于《美国心脏杂志》(Am Heart J)。

  此项研究共纳入11例HFPEF患者和13例健康对照者。采用有创右心导管测定Starling和左室压力-容积曲线;次要功能转归包括超声心动图、动脉硬度、心肺运动试验和心室-动脉偶联。7例HFPEF患者完成1年耐力训练并接受重复检查。基线时测定肺毛细血管楔压和左室舒张末期容积,通过压力-容积曲线斜度评估左室顺应性。

  结果显示,与对照组相比,训练之前HFPEF患者的运动能力、膨胀性、动态Starling机制均减弱,充盈压和室壁应力升高,但左室顺应性和舒张末期容积相似。为期1年的训练对左室顺应性和容积、动脉硬度、运动能力和心室-动脉偶联均影响甚微。

  链接:Cardiovascular effects of 1 year of progressive endurance exercise training in patients with heart failure with preserved ejection fraction



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    2012-11-09 zhaojie88
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    2012-11-09 slcumt