J HEPATOL:2型糖尿病患者发生严重肝病的风险更大

2016-04-13 MedSci MedSci原创

最新研究显示,2型糖尿病患者比没有糖尿病的人群发生严重肝病的风险更大。原始出处:H. Wild, Joanne R. Morling, David A. McAllister,et al.Type 2 diabetes and risk of hospital admission or death for chronic liver diseases,Journal of Hepatology,2

最新研究显示,2型糖尿病患者比没有糖尿病的人群发生严重肝病的风险更大。

研究人员警告说,如果2型糖尿病患者的发病率按照现在的速度持续增加,那么肝脏疾病引起的住院率和死亡人数有可能会上升。

来自南安普顿和爱丁堡大学的研究人员,研究了匿名糖尿病患者中患肝脏疾病的情况,并且安全的链接到苏格兰超过10年的医院记录和死亡记录。

他们发现,大多数2型糖尿病患者肝脏病例都是非酒精相关的,是由于脂肪在肝细胞内积聚所致—这种病例被称为非酒精性脂肪肝病(NAFLD)。

NAFLD通常与肥胖有关,这也是2型糖尿病的危险因素。

大多数人能通过健康的饮食和定期进行体育锻炼避免发生这种情况。

该研究小组发现,2型糖尿病男性患者比非糖尿病患者患NAFLD的几率高三倍。

研究发现,女性中2型糖尿病和肝病比较少见,但患有2型糖尿病会增加NAFLD五倍的风险。

NAFLD(这也增加了威胁生命的并发症,如肝硬化和肝癌的风险)的治疗选择也是有限的。

该研究涉及来自苏格兰和南安普敦糖尿病和肝病学组的研究人员。该研究发表在ournal of Hepatology杂志上,并通过苏格兰政府苏格兰糖尿病组资助。

爱丁堡大学的人口健康科学研究所Sarah Wild教授说:“在糖尿病和非糖尿病两种人群中,可以通过避免不良生活方式来预防非酒精性脂肪性肝病是非常重要的,因为这种疾病的并发症很难治疗。”

南安普敦大学和南安普敦生物医学研究中心国家健康研究所Chris Byrne教授说:“我们的研究第一次表明,2型糖尿病是增加所有慢性肝病患者的住院和死亡率的一个重要新的危险因素。现在还需要进一步的研究来确定是否所有糖尿病患者都能进行常见慢性肝病的筛查。”

原始出处:

H. Wild, Joanne R. Morling, David A. McAllister,et al.Type 2 diabetes and risk of hospital admission or death for chronic liver diseases,Journal of Hepatology,2016.4.12

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    2016-04-19 1dea6088m20(暂无匿称)

    糖尿病基数坛大非酒精脂肪肝相应坛多控能与运动干预不夠对肝病发生坛多不可避免地发生

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    2016-04-16 1dea6088m20(暂无匿称)

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    2016-04-14 gwc384
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    2016-04-14 李继凯

    高大上的文章

    0

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    2016-04-14 李继凯

    值得学习

    0

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