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BMC Urol：高压氧治疗对纤维肌痛相关性间质性膀胱炎患者的临床和形态学影响

2020-10-02 MedSci原创 MedSci原创

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间质性膀胱炎(IC)是一种膀胱衰弱性疾病，其病因多样，而且对微循环反复损害的原因了解甚少。另外纤维肌痛(FM)也是一种顽固性疾病，其病因尚未完全解释，其理论上的疼痛处理改变会影响生活质量。这两种疾病的

间质性膀胱炎(IC)是一种膀胱衰弱性疾病，其病因多样，而且对微循环反复损害的原因了解甚少。另外纤维肌痛(FM)也是一种顽固性疾病，其病因尚未完全解释，其理论上的疼痛处理改变会影响生活质量。这两种疾病的常规治疗失败的发生率很高，但最近的文献表明，高压氧治疗（HBOT）有显著的有益反应。本研究评估了HBOT对IC和FM患者的生活质量、症状、尿动力学参数和膀胱镜检查的影响，研究结果已在线发表于BMC Urol。

研究人员构建了一个观察性临床试验设计，在治疗IC和FM患者的治疗方案之前和之后6个月进行重复测量（问卷调查、尿动力学测试和膀胱镜检查）。患者使用口鼻面罩在多处压力室中暴露于2 atm绝对值（ATA）的100%氧气呼吸90分钟。患者每周5天进行一个周期的20次治疗，暂停1周后再进行第二个周期的20次治疗。

 

最终12名患者完成了治疗方案。除水肿耐受性外，HBOT后的变化不明显（治疗前平均：409.2ml；治疗后平均：489.2ml；P <0.05）。HBOT完成后6个月，瘀斑和Hunner's溃疡也逐渐消退。

综上所述，该研究结果表明，除了水肿，症状，生活质量和尿动力学参数没有改善，膀胱镜检查模式也有轻微改善。然而，到目前为止，我们无法证明总体结果对证明IC和FM患者单独使用HBOT是有意义的。这一观察结果表明，需要更多的研究来更好地了解HBOT是否可以治疗这部分患者。

 

原始出处：

 

Gerardo Bosco, Edoardo Ostardo, et al., Clinical and morphological effects of hyperbaric oxygen therapy in patients with interstitial cystitis associated with fibromyalgia. BMC Urol. 2019 Nov 5;19(1):108. doi: 10.1186/s12894-019-0545-6.

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    2021-07-28 一叶知秋

    #间质性#

    0

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    2020-10-10 ms3025846204744509

    #BMC#

    0

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    2021-03-16 xirongguo

    #高压氧治疗#

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1815826, encodeId=831918158263c, content=<a href='/topic/show?id=82e99e291b0' target=_blank style='color:#2F92EE;'>#间质性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97291, encryptionId=82e99e291b0, topicName=间质性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Wed Jul 28 12:45:04 CST 2021, time=2021-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1975035, encodeId=f3d919e50357c, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Sat Oct 10 02:45:04 CST 2020, time=2020-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1945549, encodeId=07921945549a1, content=<a href='/topic/show?id=883b1022829a' target=_blank style='color:#2F92EE;'>#高压氧治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102282, encryptionId=883b1022829a, topicName=高压氧治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=50ba440, createdName=xirongguo, createdTime=Tue Mar 16 04:45:04 CST 2021, time=2021-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=895236, encodeId=1b8a895236cc, content=及时的很，正在看相关资料, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c52a105407, createdName=check, createdTime=Thu Oct 29 04:12:49 CST 2020, time=2020-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1719445, encodeId=61b31e19445e7, content=<a href='/topic/show?id=622c9e2980d' target=_blank style='color:#2F92EE;'>#间质性膀胱炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97298, encryptionId=622c9e2980d, topicName=间质性膀胱炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=84a132724427, createdName=lixiao3337, createdTime=Fri Jun 25 21:45:04 CST 2021, time=2021-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=893284, encodeId=571889328491, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0bfc5399907, createdName=ms8000000226979895, createdTime=Tue Oct 20 14:04:25 CST 2020, time=2020-10-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1837881, encodeId=0279183e88121, content=<a href='/topic/show?id=3f34e253206' target=_blank style='color:#2F92EE;'>#相关性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72532, encryptionId=3f34e253206, topicName=相关性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Fri May 28 23:45:04 CST 2021, time=2021-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=890157, encodeId=dd5c89015e30, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200814/81d08245657a4a7f9a1ef713c0ec5878/ec4b201a22194a319b1aeb171bc6bb3d.jpg, createdBy=41e02111625, createdName=1581f8c42cm, createdTime=Mon Oct 05 07:38:26 CST 2020, time=2020-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1401589, encodeId=299c140158904, content=<a href='/topic/show?id=e3681022810d' target=_blank style='color:#2F92EE;'>#高压氧#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102281, encryptionId=e3681022810d, topicName=高压氧)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=52152357213, createdName=陈吴1235, createdTime=Sat Oct 03 16:45:04 CST 2020, time=2020-10-03, status=1, ipAttribution=)]
    2020-10-29 check

    及时的很，正在看相关资料

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1815826, encodeId=831918158263c, content=<a href='/topic/show?id=82e99e291b0' target=_blank style='color:#2F92EE;'>#间质性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97291, encryptionId=82e99e291b0, topicName=间质性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Wed Jul 28 12:45:04 CST 2021, time=2021-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1975035, encodeId=f3d919e50357c, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Sat Oct 10 02:45:04 CST 2020, time=2020-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1945549, encodeId=07921945549a1, content=<a href='/topic/show?id=883b1022829a' target=_blank style='color:#2F92EE;'>#高压氧治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102282, encryptionId=883b1022829a, topicName=高压氧治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=50ba440, createdName=xirongguo, createdTime=Tue Mar 16 04:45:04 CST 2021, time=2021-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=895236, encodeId=1b8a895236cc, content=及时的很，正在看相关资料, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c52a105407, createdName=check, createdTime=Thu Oct 29 04:12:49 CST 2020, time=2020-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1719445, encodeId=61b31e19445e7, content=<a href='/topic/show?id=622c9e2980d' target=_blank style='color:#2F92EE;'>#间质性膀胱炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97298, encryptionId=622c9e2980d, topicName=间质性膀胱炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=84a132724427, createdName=lixiao3337, createdTime=Fri Jun 25 21:45:04 CST 2021, time=2021-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=893284, encodeId=571889328491, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0bfc5399907, createdName=ms8000000226979895, createdTime=Tue Oct 20 14:04:25 CST 2020, time=2020-10-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1837881, encodeId=0279183e88121, content=<a href='/topic/show?id=3f34e253206' target=_blank style='color:#2F92EE;'>#相关性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72532, encryptionId=3f34e253206, topicName=相关性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Fri May 28 23:45:04 CST 2021, time=2021-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=890157, encodeId=dd5c89015e30, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200814/81d08245657a4a7f9a1ef713c0ec5878/ec4b201a22194a319b1aeb171bc6bb3d.jpg, createdBy=41e02111625, createdName=1581f8c42cm, createdTime=Mon Oct 05 07:38:26 CST 2020, time=2020-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1401589, encodeId=299c140158904, content=<a href='/topic/show?id=e3681022810d' target=_blank style='color:#2F92EE;'>#高压氧#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102281, encryptionId=e3681022810d, topicName=高压氧)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=52152357213, createdName=陈吴1235, createdTime=Sat Oct 03 16:45:04 CST 2020, time=2020-10-03, status=1, ipAttribution=)]
    2021-06-25 lixiao3337

    #间质性膀胱炎#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1815826, encodeId=831918158263c, content=<a href='/topic/show?id=82e99e291b0' target=_blank style='color:#2F92EE;'>#间质性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97291, encryptionId=82e99e291b0, topicName=间质性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Wed Jul 28 12:45:04 CST 2021, time=2021-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1975035, encodeId=f3d919e50357c, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Sat Oct 10 02:45:04 CST 2020, time=2020-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1945549, encodeId=07921945549a1, content=<a href='/topic/show?id=883b1022829a' target=_blank style='color:#2F92EE;'>#高压氧治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102282, encryptionId=883b1022829a, topicName=高压氧治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=50ba440, createdName=xirongguo, createdTime=Tue Mar 16 04:45:04 CST 2021, time=2021-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=895236, encodeId=1b8a895236cc, content=及时的很，正在看相关资料, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c52a105407, createdName=check, createdTime=Thu Oct 29 04:12:49 CST 2020, time=2020-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1719445, encodeId=61b31e19445e7, content=<a href='/topic/show?id=622c9e2980d' target=_blank style='color:#2F92EE;'>#间质性膀胱炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97298, encryptionId=622c9e2980d, topicName=间质性膀胱炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=84a132724427, createdName=lixiao3337, createdTime=Fri Jun 25 21:45:04 CST 2021, time=2021-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=893284, encodeId=571889328491, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0bfc5399907, createdName=ms8000000226979895, createdTime=Tue Oct 20 14:04:25 CST 2020, time=2020-10-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1837881, encodeId=0279183e88121, content=<a href='/topic/show?id=3f34e253206' target=_blank style='color:#2F92EE;'>#相关性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72532, encryptionId=3f34e253206, topicName=相关性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Fri May 28 23:45:04 CST 2021, time=2021-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=890157, encodeId=dd5c89015e30, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200814/81d08245657a4a7f9a1ef713c0ec5878/ec4b201a22194a319b1aeb171bc6bb3d.jpg, createdBy=41e02111625, createdName=1581f8c42cm, createdTime=Mon Oct 05 07:38:26 CST 2020, time=2020-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1401589, encodeId=299c140158904, content=<a href='/topic/show?id=e3681022810d' target=_blank style='color:#2F92EE;'>#高压氧#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102281, encryptionId=e3681022810d, topicName=高压氧)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=52152357213, createdName=陈吴1235, createdTime=Sat Oct 03 16:45:04 CST 2020, time=2020-10-03, status=1, ipAttribution=)]
    2020-10-20 ms8000000226979895

    学习

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1815826, encodeId=831918158263c, content=<a href='/topic/show?id=82e99e291b0' target=_blank style='color:#2F92EE;'>#间质性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97291, encryptionId=82e99e291b0, topicName=间质性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Wed Jul 28 12:45:04 CST 2021, time=2021-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1975035, encodeId=f3d919e50357c, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Sat Oct 10 02:45:04 CST 2020, time=2020-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1945549, encodeId=07921945549a1, content=<a href='/topic/show?id=883b1022829a' target=_blank style='color:#2F92EE;'>#高压氧治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102282, encryptionId=883b1022829a, topicName=高压氧治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=50ba440, createdName=xirongguo, createdTime=Tue Mar 16 04:45:04 CST 2021, time=2021-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=895236, encodeId=1b8a895236cc, content=及时的很，正在看相关资料, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c52a105407, createdName=check, createdTime=Thu Oct 29 04:12:49 CST 2020, time=2020-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1719445, encodeId=61b31e19445e7, content=<a href='/topic/show?id=622c9e2980d' target=_blank style='color:#2F92EE;'>#间质性膀胱炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97298, encryptionId=622c9e2980d, topicName=间质性膀胱炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=84a132724427, createdName=lixiao3337, createdTime=Fri Jun 25 21:45:04 CST 2021, time=2021-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=893284, encodeId=571889328491, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0bfc5399907, createdName=ms8000000226979895, createdTime=Tue Oct 20 14:04:25 CST 2020, time=2020-10-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1837881, encodeId=0279183e88121, content=<a href='/topic/show?id=3f34e253206' target=_blank style='color:#2F92EE;'>#相关性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72532, encryptionId=3f34e253206, topicName=相关性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Fri May 28 23:45:04 CST 2021, time=2021-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=890157, encodeId=dd5c89015e30, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200814/81d08245657a4a7f9a1ef713c0ec5878/ec4b201a22194a319b1aeb171bc6bb3d.jpg, createdBy=41e02111625, createdName=1581f8c42cm, createdTime=Mon Oct 05 07:38:26 CST 2020, time=2020-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1401589, encodeId=299c140158904, content=<a href='/topic/show?id=e3681022810d' target=_blank style='color:#2F92EE;'>#高压氧#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102281, encryptionId=e3681022810d, topicName=高压氧)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=52152357213, createdName=陈吴1235, createdTime=Sat Oct 03 16:45:04 CST 2020, time=2020-10-03, status=1, ipAttribution=)]
    2021-05-28 shenxlcyp

    #相关性#

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1815826, encodeId=831918158263c, content=<a href='/topic/show?id=82e99e291b0' target=_blank style='color:#2F92EE;'>#间质性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97291, encryptionId=82e99e291b0, topicName=间质性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Wed Jul 28 12:45:04 CST 2021, time=2021-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1975035, encodeId=f3d919e50357c, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Sat Oct 10 02:45:04 CST 2020, time=2020-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1945549, encodeId=07921945549a1, content=<a href='/topic/show?id=883b1022829a' target=_blank style='color:#2F92EE;'>#高压氧治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102282, encryptionId=883b1022829a, topicName=高压氧治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=50ba440, createdName=xirongguo, createdTime=Tue Mar 16 04:45:04 CST 2021, time=2021-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=895236, encodeId=1b8a895236cc, content=及时的很，正在看相关资料, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c52a105407, createdName=check, createdTime=Thu Oct 29 04:12:49 CST 2020, time=2020-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1719445, encodeId=61b31e19445e7, content=<a href='/topic/show?id=622c9e2980d' target=_blank style='color:#2F92EE;'>#间质性膀胱炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97298, encryptionId=622c9e2980d, topicName=间质性膀胱炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=84a132724427, createdName=lixiao3337, createdTime=Fri Jun 25 21:45:04 CST 2021, time=2021-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=893284, encodeId=571889328491, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0bfc5399907, createdName=ms8000000226979895, createdTime=Tue Oct 20 14:04:25 CST 2020, time=2020-10-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1837881, encodeId=0279183e88121, content=<a href='/topic/show?id=3f34e253206' target=_blank style='color:#2F92EE;'>#相关性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72532, encryptionId=3f34e253206, topicName=相关性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Fri May 28 23:45:04 CST 2021, time=2021-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=890157, encodeId=dd5c89015e30, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200814/81d08245657a4a7f9a1ef713c0ec5878/ec4b201a22194a319b1aeb171bc6bb3d.jpg, createdBy=41e02111625, createdName=1581f8c42cm, createdTime=Mon Oct 05 07:38:26 CST 2020, time=2020-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1401589, encodeId=299c140158904, content=<a href='/topic/show?id=e3681022810d' target=_blank style='color:#2F92EE;'>#高压氧#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102281, encryptionId=e3681022810d, topicName=高压氧)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=52152357213, createdName=陈吴1235, createdTime=Sat Oct 03 16:45:04 CST 2020, time=2020-10-03, status=1, ipAttribution=)]
    2020-10-05 1581f8c42cm

    学习

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1815826, encodeId=831918158263c, content=<a href='/topic/show?id=82e99e291b0' target=_blank style='color:#2F92EE;'>#间质性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97291, encryptionId=82e99e291b0, topicName=间质性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Wed Jul 28 12:45:04 CST 2021, time=2021-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1975035, encodeId=f3d919e50357c, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Sat Oct 10 02:45:04 CST 2020, time=2020-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1945549, encodeId=07921945549a1, content=<a href='/topic/show?id=883b1022829a' target=_blank style='color:#2F92EE;'>#高压氧治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102282, encryptionId=883b1022829a, topicName=高压氧治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=50ba440, createdName=xirongguo, createdTime=Tue Mar 16 04:45:04 CST 2021, time=2021-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=895236, encodeId=1b8a895236cc, content=及时的很，正在看相关资料, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c52a105407, createdName=check, createdTime=Thu Oct 29 04:12:49 CST 2020, time=2020-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1719445, encodeId=61b31e19445e7, content=<a href='/topic/show?id=622c9e2980d' target=_blank style='color:#2F92EE;'>#间质性膀胱炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97298, encryptionId=622c9e2980d, topicName=间质性膀胱炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=84a132724427, createdName=lixiao3337, createdTime=Fri Jun 25 21:45:04 CST 2021, time=2021-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=893284, encodeId=571889328491, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0bfc5399907, createdName=ms8000000226979895, createdTime=Tue Oct 20 14:04:25 CST 2020, time=2020-10-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1837881, encodeId=0279183e88121, content=<a href='/topic/show?id=3f34e253206' target=_blank style='color:#2F92EE;'>#相关性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72532, encryptionId=3f34e253206, topicName=相关性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Fri May 28 23:45:04 CST 2021, time=2021-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=890157, encodeId=dd5c89015e30, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200814/81d08245657a4a7f9a1ef713c0ec5878/ec4b201a22194a319b1aeb171bc6bb3d.jpg, createdBy=41e02111625, createdName=1581f8c42cm, createdTime=Mon Oct 05 07:38:26 CST 2020, time=2020-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1401589, encodeId=299c140158904, content=<a href='/topic/show?id=e3681022810d' target=_blank style='color:#2F92EE;'>#高压氧#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102281, encryptionId=e3681022810d, topicName=高压氧)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=52152357213, createdName=陈吴1235, createdTime=Sat Oct 03 16:45:04 CST 2020, time=2020-10-03, status=1, ipAttribution=)]
    2020-10-03 陈吴1235

    #高压氧#

    0