HRS 2014:MRI有望锁定射频消融靶标

2014-05-16 中山大学孙逸仙纪念医院 谢双伦 医学论坛网

在本次美国心律学会(HRS)年会上,各国学者对当代医疗科技进展作了深刻的回顾和展望。本次会议的一个独特之处就是发现或寻找科技与医学之间的交汇点,更好地利用二者之间的关系推动心电生理学发展。科技正在不断地重塑临床实践和改善患者预后。 美国约翰斯·霍普金斯医院特亚诺娃(Natalia Trayanova)教授在题为“三维心脏模型重建”的报告中指出,她和她的同事正在尝试建立一个基于磁共振成像(MRI)

在本次美国心律学会(HRS)年会上,各国学者对当代医疗科技进展作了深刻的回顾和展望。本次会议的一个独特之处就是发现或寻找科技与医学之间的交汇点,更好地利用二者之间的关系推动心电生理学发展。科技正在不断地重塑临床实践和改善患者预后。

美国约翰斯·霍普金斯医院特亚诺娃(Natalia Trayanova)教授在题为“三维心脏模型重建”的报告中指出,她和她的同事正在尝试建立一个基于磁共振成像(MRI)建模环境的虚拟电生理实验室模型,以便从分子水平获取证据来帮助特异个体患者诊断和治疗。Trayanova教授强调,该尝试的主要目的是为了发展和建立多层模型平台,将来可能在某种程度上能精确绘制出室性心动过速消融的最佳靶点。但她同时指出,目前该方法尚不能在临床应用。

Trayanova教授指出,基于传统导管标测建模的室速消融成功率约为51%,在消融前行MRI检查并利用图像处理软件可模拟所有心律不齐,这能够预测最终的消融目标。应用MRI可完全无创地识别消融靶点,减小消融病变范围,提高治疗耐受性。

Trayanova教授等采用的方法是通过一个非特异集合的组内插技术详细地标测梗死区域,将二维层面转为三维模型。心肌纤维走向是建立这个模型的一部分,因此需要将心肌纤维走向覆盖到每例患者的心脏上,就会产生一个完整的心脏的几何模型。

Trayanova教授在犬和猪中开展的研究证实,MRI数据将使电生理医生紧紧瞄准感兴趣的组织,从而减少组织暴露量。如果这一变革性方法成功,将会带来临床电生理治疗模式的新转变。

中山大学孙逸仙纪念医院 谢双伦

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    2014-05-18 zhaojie88
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    2014-05-18 智慧医人
  6. [GetPortalCommentsPageByObjectIdResponse(id=2056808, encodeId=c22a2056808f2, content=<a href='/topic/show?id=1a12468266b' target=_blank style='color:#2F92EE;'>#射频消融靶标#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46826, encryptionId=1a12468266b, topicName=射频消融靶标)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3c5e117, createdName=lujian, createdTime=Mon Dec 01 08:08:00 CST 2014, time=2014-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1279907, encodeId=1a5312e99072b, content=<a href='/topic/show?id=0b0546822fd' target=_blank style='color:#2F92EE;'>#射频消融#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46822, encryptionId=0b0546822fd, topicName=射频消融)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dc7a157, createdName=jinweidong, createdTime=Sun May 18 02:08:00 CST 2014, time=2014-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1352724, encodeId=3c501352e24c6, content=<a href='/topic/show?id=827d9996311' target=_blank style='color:#2F92EE;'>#靶标#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99963, encryptionId=827d9996311, topicName=靶标)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Sun May 18 02:08:00 CST 2014, time=2014-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1421594, encodeId=3eeb142159455, content=<a href='/topic/show?id=4bc865819d2' target=_blank style='color:#2F92EE;'>#消融#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65819, encryptionId=4bc865819d2, topicName=消融)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Sun May 18 02:08:00 CST 2014, time=2014-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1464104, encodeId=a3bc1464104c1, content=<a href='/topic/show?id=da7d9119bc' target=_blank style='color:#2F92EE;'>#HRS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9119, encryptionId=da7d9119bc, topicName=HRS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智慧医人, createdTime=Sun May 18 02:08:00 CST 2014, time=2014-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=9491, encodeId=ca1294914d, content=随着场强增加,以及新的序列出现,MR在靶区勾画方面也越来越显示出优势,加上无创作用。将来潜力巨大, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=139.227.156.102, createdTime=Fri May 16 17:06:00 CST 2014, time=2014-05-16, status=1, ipAttribution=)]
    2014-05-16 139.227.156.102

    随着场强增加,以及新的序列出现,MR在靶区勾画方面也越来越显示出优势,加上无创作用。将来潜力巨大

    0

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